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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rfc4. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 8 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication factor C complex 3.528E-10 8 11 4 6292
replication fork 1.1779E-7 8 42 4 6292
chromosomal part 1.2193E-4 8 237 4 6292
chromosome 2.1439E-4 8 274 4 6292
non-membrane-bounded organelle 3.0487E-3 8 959 5 6292
intracellular non-membrane-bounded organelle 3.0487E-3 8 959 5 6292
methionyl glutamyl tRNA synthetase complex 5.0773E-3 8 4 1 6292
protein complex 6.5954E-3 8 1137 5 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

leading strand elongation 6.0965E-7 8 15 3 6292
mismatch repair 3.8912E-6 8 27 3 6292
DNA strand elongation 5.9655E-6 8 31 3 6292
DNA strand elongation involved in DNA replication 5.9655E-6 8 31 3 6292
DNA replication 9.1645E-6 8 123 4 6292
DNA repair 5.3445E-5 8 192 4 6292
response to stimulus 7.2011E-5 8 766 6 6292
DNA-dependent DNA replication 1.1399E-4 8 82 3 6292
response to DNA damage stimulus 1.1994E-4 8 236 4 6292
response to stress 1.3812E-4 8 497 5 6292
cellular response to stress 2.671E-4 8 290 4 6292
sister chromatid cohesion 6.8844E-4 8 32 2 6292
cellular response to stimulus 7.4705E-4 8 379 4 6292
chromosome organization 3.1417E-3 8 555 4 6292
glutamyl-tRNA aminoacylation 3.8101E-3 8 3 1 6292
DNA metabolic process 3.8176E-3 8 585 4 6292
cellular biosynthetic process 4.1159E-3 8 1567 6 6292
biosynthetic process 4.6438E-3 8 1602 6 6292
citrate metabolic process 5.0773E-3 8 4 1 6292
organelle organization 6.3392E-3 8 1127 5 6292
propionate metabolic process 6.3431E-3 8 5 1 6292
cellular nitrogen compound metabolic process 7.9712E-3 8 1770 6 6292
cellular macromolecule biosynthetic process 7.9943E-3 8 1187 5 6292
macromolecule biosynthetic process 8.0545E-3 8 1189 5 6292
nitrogen compound metabolic process 8.4927E-3 8 1791 6 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA clamp loader activity 4.7121E-8 8 7 3 6292
protein-DNA loading ATPase activity 4.7121E-8 8 7 3 6292
DNA-dependent ATPase activity 3.4321E-5 8 55 3 6292
ATPase activity, coupled 6.6794E-4 8 149 3 6292
purine nucleotide binding 1.8172E-3 8 52 2 6292
ATPase activity 1.8378E-3 8 211 3 6292
nucleotide binding 2.3343E-3 8 59 2 6292
aconitate hydratase activity 2.5415E-3 8 2 1 6292
DNA binding 3.2017E-3 8 256 3 6292
glutamate-tRNA ligase activity 3.8101E-3 8 3 1 6292
nucleoside-triphosphatase activity 6.5162E-3 8 329 3 6292
hydrolase activity, acting on acid anhydrides 7.936E-3 8 353 3 6292
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 7.936E-3 8 353 3 6292
pyrophosphatase activity 7.936E-3 8 353 3 6292

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