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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rfc4. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 9 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication factor C complex 3.321E-7 9 11 3 6292
replication fork 2.2598E-5 9 42 3 6292
chromosomal part 3.7449E-3 9 237 3 6292
chromosome 5.6423E-3 9 274 3 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

leading strand elongation 9.1317E-7 9 15 3 6292
mismatch repair 5.8201E-6 9 27 3 6292
DNA strand elongation 8.9184E-6 9 31 3 6292
DNA strand elongation involved in DNA replication 8.9184E-6 9 31 3 6292
DNA-dependent DNA replication 1.6938E-4 9 82 3 6292
response to stress 2.9062E-4 9 497 5 6292
DNA replication 5.6194E-4 9 123 3 6292
sister chromatid cohesion 8.8233E-4 9 32 2 6292
primary metabolic process 9.2081E-4 9 2896 9 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.294E-3 9 1566 7 6292
cellular metabolic process 1.3966E-3 9 3033 9 6292
chaperone-mediated protein folding 1.4304E-3 9 1 1 6292
'de novo' posttranslational protein folding 1.4304E-3 9 1 1 6292
chaperone mediated protein folding requiring cofactor 1.4304E-3 9 1 1 6292
metabolic process 2.004E-3 9 3157 9 6292
DNA repair 2.0512E-3 9 192 3 6292
response to stimulus 2.1816E-3 9 766 5 6292
cellular nitrogen compound metabolic process 2.8378E-3 9 1770 7 6292
nitrogen compound metabolic process 3.0588E-3 9 1791 7 6292
response to DNA damage stimulus 3.7002E-3 9 236 3 6292
protein folding 5.1625E-3 9 78 2 6292
DNA metabolic process 6.3704E-3 9 585 4 6292
cellular response to stress 6.6158E-3 9 290 3 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA clamp loader activity 7.0647E-8 9 7 3 6292
protein-DNA loading ATPase activity 7.0647E-8 9 7 3 6292
ATPase activity 4.5683E-6 9 211 5 6292
ATPase activity, coupled 3.4703E-5 9 149 4 6292
nucleoside-triphosphatase activity 4.0153E-5 9 329 5 6292
DNA-dependent ATPase activity 5.1163E-5 9 55 3 6292
hydrolase activity, acting on acid anhydrides 5.6462E-5 9 353 5 6292
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 5.6462E-5 9 353 5 6292
pyrophosphatase activity 5.6462E-5 9 353 5 6292
chaperone binding 1.6406E-4 9 14 2 6292
catalytic activity 1.156E-3 9 2150 8 6292
phosphoribosylformylglycinamidine cyclo-ligase activity 1.4304E-3 9 1 1 6292
phosphoribosylamine-glycine ligase activity 1.4304E-3 9 1 1 6292
purine nucleotide binding 2.324E-3 9 52 2 6292
proline-tRNA ligase activity 2.859E-3 9 2 1 6292
nucleotide binding 2.9832E-3 9 59 2 6292
chaperone activator activity 4.2857E-3 9 3 1 6292
cyclo-ligase activity 4.2857E-3 9 3 1 6292
DNA binding 4.6591E-3 9 256 3 6292
hydrolase activity 4.7759E-3 9 911 5 6292
alcohol dehydrogenase (NAD) activity 9.9746E-3 9 7 1 6292
ATPase activator activity 9.9746E-3 9 7 1 6292

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