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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Ela1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 7 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

organelle lumen 1.3579E-7 7 660 7 6292
intracellular organelle lumen 1.3579E-7 7 660 7 6292
membrane-enclosed lumen 2.0537E-7 7 700 7 6292
nucleolus 8.0465E-7 7 211 5 6292
nuclear lumen 8.8765E-7 7 453 6 6292
nuclear part 1.7083E-4 7 1103 6 6292
intracellular organelle part 8.2061E-4 7 2282 7 6292
organelle part 8.2061E-4 7 2282 7 6292
non-membrane-bounded organelle 1.3072E-3 7 959 5 6292
intracellular non-membrane-bounded organelle 1.3072E-3 7 959 5 6292
small nucleolar ribonucleoprotein complex 2.6131E-3 7 72 2 6292
nuclear outer membrane 3.7089E-3 7 86 2 6292
Cul3-RING ubiquitin ligase complex 4.4437E-3 7 4 1 6292
nuclear membrane 4.6971E-3 7 97 2 6292
nucleus 5.8629E-3 7 2041 6 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

ribosomal large subunit biogenesis 3.5765E-5 7 65 3 6292
ribosome biogenesis 2.7556E-4 7 346 4 6292
rRNA metabolic process 3.3156E-4 7 137 3 6292
ribonucleoprotein complex biogenesis 3.725E-4 7 374 4 6292
ribosomal large subunit assembly 8.5225E-4 7 41 2 6292
RNA metabolic process 1.2754E-3 7 954 5 6292
ribosomal subunit assembly 1.532E-3 7 55 2 6292
maturation of SSU-rRNA 1.7614E-3 7 59 2 6292
ribosome assembly 2.0698E-3 7 64 2 6292
ncRNA metabolic process 2.0862E-3 7 257 3 6292
organelle assembly 2.4022E-3 7 69 2 6292
cellular component biogenesis 3.9065E-3 7 694 4 6292
ribonucleoprotein complex assembly 4.2342E-3 7 92 2 6292
snoRNA 3'-end processing 5.552E-3 7 5 1 6292
RNA processing 6.3721E-3 7 380 3 6292
snoRNA processing 7.7654E-3 7 7 1 6292
nucleic acid metabolic process 7.9545E-3 7 1415 5 6292
rRNA processing 8.0653E-3 7 128 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

RNA binding 3.4624E-4 7 367 4 6292
7S RNA binding 1.1125E-3 7 1 1 6292
5S rRNA binding 2.224E-3 7 2 1 6292
nucleic acid binding 3.3506E-3 7 666 4 6292
binding 5.2851E-3 7 1294 5 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle