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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Gbp2. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 8 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

THO complex 1.0729E-12 8 4 4 6292
transcription export complex 8.4777E-6 8 4 2 6292
nuclear part 5.8147E-4 8 1103 6 6292
protein complex 6.9038E-4 8 1137 6 6292
nucleus 2.1521E-3 8 2041 7 6292
macromolecular complex 5.1894E-3 8 1635 6 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

mRNA transport 9.9602E-14 8 68 7 6292
mRNA export from nucleus 9.9602E-14 8 68 7 6292
RNA export from nucleus 3.2583E-13 8 80 7 6292
RNA transport 3.566E-13 8 81 7 6292
nucleic acid transport 3.566E-13 8 81 7 6292
establishment of RNA localization 3.566E-13 8 81 7 6292
RNA localization 8.9704E-13 8 92 7 6292
nucleobase, nucleoside, nucleotide and nucleic acid transport 1.2198E-12 8 96 7 6292
nuclear export 2.0257E-12 8 103 7 6292
nuclear transport 1.0759E-11 8 130 7 6292
nucleocytoplasmic transport 1.0759E-11 8 130 7 6292
macromolecule localization 2.8656E-8 8 397 7 6292
RNA elongation from RNA polymerase II promoter 8.6688E-8 8 39 4 6292
RNA elongation 1.5655E-7 8 45 4 6292
intracellular transport 2.892E-7 8 553 7 6292
establishment of localization in cell 5.0393E-7 8 599 7 6292
cellular localization 8.2414E-7 8 643 7 6292
DNA recombination 6.7673E-6 8 114 4 6292
transport 1.6995E-5 8 997 7 6292
establishment of localization 1.8323E-5 8 1008 7 6292
localization 2.5864E-5 8 1060 7 6292
transcription, DNA-dependent 1.4632E-4 8 503 5 6292
RNA biosynthetic process 1.5345E-4 8 508 5 6292
transcription 2.285E-4 8 552 5 6292
anatomical structure homeostasis 2.5313E-4 8 286 4 6292
telomere organization 2.5313E-4 8 286 4 6292
telomere maintenance 2.5313E-4 8 286 4 6292
DNA metabolic process 3.015E-4 8 585 5 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.6683E-4 8 1566 7 6292
transcription from RNA polymerase II promoter 4.6579E-4 8 335 4 6292
cellular nitrogen compound metabolic process 8.3438E-4 8 1770 7 6292
nitrogen compound metabolic process 9.0281E-4 8 1791 7 6292
homeostatic process 9.8908E-4 8 408 4 6292
nucleic acid metabolic process 2.3473E-3 8 1415 6 6292
GTP biosynthetic process 2.5415E-3 8 2 1 6292
RNA metabolic process 2.9766E-3 8 954 5 6292
regulation of biological quality 3.0585E-3 8 551 4 6292
chromosome organization 3.1417E-3 8 555 4 6292
cellular biosynthetic process 4.1159E-3 8 1567 6 6292
biosynthetic process 4.6438E-3 8 1602 6 6292
cellular macromolecule biosynthetic process 7.9943E-3 8 1187 5 6292
macromolecule biosynthetic process 8.0545E-3 8 1189 5 6292
biological regulation 8.8033E-3 8 1213 5 6292
poly(A)+ mRNA export from nucleus 8.8705E-3 8 7 1 6292
GTP metabolic process 8.8705E-3 8 7 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

nucleic acid binding 3.1964E-5 8 666 6 6292
binding 1.4278E-3 8 1294 6 6292
IMP dehydrogenase activity 3.8101E-3 8 3 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle