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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Nup85. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 6 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CBP3
  • mitochondrion
  • mitochondrial envelope
  • protein complex assembly
  • molecular_function
  • HEM15
  • mitochondrion
  • mitochondrial inner membrane
  • heme biosynthetic process
  • ferrochelatase activity
  • NUP84
  • nuclear pore
  • DNA metabolic process
  • protein export from nucleus
  • response to DNA damage stimulus
  • ribosomal protein import into nucleus
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear envelope organization
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • chromosome localization
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • structural molecule activity
  • NUP85
  • nuclear pore
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear envelope organization
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • protein export from nucleus
  • ribosomal protein import into nucleus
  • structural molecule activity
  • SEH1
  • nuclear pore
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • protein export from nucleus
  • ribosomal protein import into nucleus
  • structural molecule activity
  • YMR209C
  • cellular_component
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    pore complex 1.0466E-5 6 52 3 6292
    nuclear pore 1.0466E-5 6 52 3 6292
    envelope 1.8321E-5 6 505 5 6292
    organelle envelope 1.8321E-5 6 505 5 6292
    nuclear envelope 5.8088E-4 6 199 3 6292
    integral to membrane 1.2014E-3 6 255 3 6292
    intrinsic to membrane 1.3001E-3 6 262 3 6292
    endomembrane system 4.3509E-3 6 398 3 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosomal protein import into nucleus 8.4748E-7 6 23 3 6292
    snRNP protein import into nucleus 8.4748E-7 6 23 3 6292
    snRNA export from nucleus 8.4748E-7 6 23 3 6292
    NLS-bearing substrate import into nucleus 8.4748E-7 6 23 3 6292
    snRNA transport 8.4748E-7 6 23 3 6292
    mRNA-binding (hnRNP) protein import into nucleus 1.0998E-6 6 25 3 6292
    rRNA export from nucleus 1.3977E-6 6 27 3 6292
    rRNA transport 1.3977E-6 6 27 3 6292
    nuclear pore organization 1.5649E-6 6 28 3 6292
    tRNA export from nucleus 1.5649E-6 6 28 3 6292
    tRNA transport 1.5649E-6 6 28 3 6292
    protein export from nucleus 2.3659E-6 6 32 3 6292
    nuclear import 8.2027E-6 6 48 3 6292
    protein localization in nucleus 8.2027E-6 6 48 3 6292
    protein import into nucleus 8.2027E-6 6 48 3 6292
    nucleus organization 1.3109E-5 6 56 3 6292
    nuclear envelope organization 1.5882E-5 6 7 2 6292
    mRNA export from nucleus 2.3597E-5 6 68 3 6292
    mRNA transport 2.3597E-5 6 68 3 6292
    RNA export from nucleus 3.8518E-5 6 80 3 6292
    RNA transport 3.9986E-5 6 81 3 6292
    nucleic acid transport 3.9986E-5 6 81 3 6292
    establishment of RNA localization 3.9986E-5 6 81 3 6292
    RNA localization 5.862E-5 6 92 3 6292
    nucleobase, nucleoside, nucleotide and nucleic acid transport 6.66E-5 6 96 3 6292
    nuclear export 8.2226E-5 6 103 3 6292
    protein import 9.475E-5 6 108 3 6292
    macromolecular complex subunit organization 1.3958E-4 6 357 4 6292
    nuclear transport 1.6472E-4 6 130 3 6292
    nucleocytoplasmic transport 1.6472E-4 6 130 3 6292
    protein localization in organelle 2.4704E-4 6 149 3 6292
    protein targeting 9.4628E-4 6 235 3 6292
    intracellular protein transport 1.2014E-3 6 255 3 6292
    cellular macromolecular complex subunit organization 1.2572E-3 6 259 3 6292
    protein transport 1.404E-3 6 269 3 6292
    establishment of protein localization 1.4346E-3 6 271 3 6292
    cellular protein localization 1.4813E-3 6 274 3 6292
    cellular macromolecule localization 1.644E-3 6 284 3 6292
    cellular component biogenesis 1.8339E-3 6 694 4 6292
    protein localization 1.984E-3 6 303 3 6292
    ribosome biogenesis 2.9111E-3 6 346 3 6292
    ribonucleoprotein complex biogenesis 3.641E-3 6 374 3 6292
    chromosome localization 3.8098E-3 6 4 1 6292
    macromolecule localization 4.3197E-3 6 397 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ferrochelatase activity 1.9064E-3 6 2 1 6292
    structural molecule activity 2.7446E-3 6 339 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle