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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Cdc53. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 3 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

SCF ubiquitin ligase complex 8.329E-6 3 11 2 6292
cullin-RING ubiquitin ligase complex 1.3776E-5 3 14 2 6292
ubiquitin ligase complex 1.3628E-4 3 43 2 6292
RAVE complex 1.4299E-3 3 3 1 6292
CBF3 complex 1.9063E-3 3 4 1 6292
integral to mitochondrial outer membrane 6.1865E-3 3 13 1 6292
intrinsic to mitochondrial outer membrane 6.1865E-3 3 13 1 6292
integral to mitochondrial membrane 6.6614E-3 3 14 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 3.1815E-6 3 7 2 6292
protein ubiquitination during ubiquitin-dependent protein catabolic process 8.329E-6 3 11 2 6292
G2/M transition of mitotic cell cycle 6.1366E-5 3 29 2 6292
G1/S transition of mitotic cell cycle 1.8474E-4 3 50 2 6292
protein ubiquitination 3.1318E-4 3 65 2 6292
proteasomal protein catabolic process 3.5308E-4 3 69 2 6292
proteasomal ubiquitin-dependent protein catabolic process 3.5308E-4 3 69 2 6292
protein modification by small protein conjugation 5.4909E-4 3 86 2 6292
interphase of mitotic cell cycle 6.9865E-4 3 97 2 6292
interphase 6.9865E-4 3 97 2 6292
protein modification by small protein conjugation or removal 9.6474E-4 3 114 2 6292
centromere complex assembly 1.4299E-3 3 3 1 6292
kinetochore assembly 1.4299E-3 3 3 1 6292
kinetochore organization 1.4299E-3 3 3 1 6292
modification-dependent protein catabolic process 1.8027E-3 3 156 2 6292
ubiquitin-dependent protein catabolic process 1.8027E-3 3 156 2 6292
proteolysis involved in cellular protein catabolic process 1.8723E-3 3 159 2 6292
modification-dependent macromolecule catabolic process 1.9912E-3 3 164 2 6292
cellular protein catabolic process 2.1638E-3 3 171 2 6292
proteolysis 2.612E-3 3 188 2 6292
protein catabolic process 2.6396E-3 3 189 2 6292
protein neddylation 3.3344E-3 3 7 1 6292
mitotic cell cycle 4.7773E-3 3 255 2 6292
cellular macromolecule catabolic process 5.1545E-3 3 265 2 6292
regulation of protein complex assembly 5.2364E-3 3 11 1 6292
macromolecule catabolic process 6.3267E-3 3 294 2 6292
regulation of cellular component biogenesis 8.5592E-3 3 18 1 6292
post-translational protein modification 9.2699E-3 3 357 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication origin binding 1.1809E-5 3 13 2 6292
sequence-specific DNA binding 1.8474E-4 3 50 2 6292
ubiquitin-protein ligase activity 2.4051E-4 3 57 2 6292
small conjugating protein ligase activity 2.8482E-4 3 62 2 6292
acid-amino acid ligase activity 3.7392E-4 3 71 2 6292
ligase activity, forming carbon-nitrogen bonds 6.561E-4 3 94 2 6292
anion channel activity 1.4299E-3 3 3 1 6292
voltage-gated anion channel activity 1.4299E-3 3 3 1 6292
ligase activity 1.6673E-3 3 150 2 6292
voltage-gated channel activity 3.8101E-3 3 8 1 6292
voltage-gated ion channel activity 3.8101E-3 3 8 1 6292
gated channel activity 4.2857E-3 3 9 1 6292
ion channel activity 4.7611E-3 3 10 1 6292
DNA binding 4.8144E-3 3 256 2 6292
passive transmembrane transporter activity 6.1865E-3 3 13 1 6292
channel activity 6.1865E-3 3 13 1 6292
substrate-specific channel activity 6.1865E-3 3 13 1 6292
protein binding, bridging 9.5071E-3 3 20 1 6292
anion transmembrane transporter activity 9.9809E-3 3 21 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle