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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rvs167. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
DED1
  • cytoplasm
  • RNA splicing
  • translational initiation
  • RNA helicase activity
  • GYP5
  • incipient cellular bud site
  • cellular bud tip
  • soluble fraction
  • cellular bud neck
  • cytosol
  • Golgi-associated vesicle
  • plasma membrane
  • ER to Golgi vesicle-mediated transport
  • vesicle-mediated transport
  • Rab GTPase activator activity
  • IDH1
  • mitochondrial matrix
  • mitochondrion
  • mitochondrial nucleoid
  • glutamate biosynthetic process
  • isocitrate metabolic process
  • tricarboxylic acid cycle
  • isocitrate dehydrogenase (NAD+) activity
  • ILV5
  • mitochondrion
  • mitochondrial nucleoid
  • branched chain family amino acid biosynthetic process
  • mitochondrial genome maintenance
  • ketol-acid reductoisomerase activity
  • LYS12
  • mitochondrion
  • lysine biosynthetic process
  • homoisocitrate dehydrogenase activity
  • MET18
  • nucleoplasm
  • telomere maintenance
  • nucleotide-excision repair
  • transcription from RNA polymerase II promoter
  • methionine metabolic process
  • RNA polymerase II transcription factor activity
  • PHO84
  • integral to plasma membrane
  • phosphate transport
  • manganese ion transport
  • inorganic phosphate transmembrane transporter activity
  • manganese ion transmembrane transporter activity
  • PRE10
  • proteasome core complex, alpha-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • RVS167
  • actin cortical patch
  • vesicle-mediated transport
  • bipolar cellular bud site selection
  • response to osmotic stress
  • endocytosis
  • cytoskeletal protein binding
  • URA7
  • cytosol
  • CTP biosynthetic process
  • phospholipid biosynthetic process
  • pyrimidine base biosynthetic process
  • CTP synthase activity
  • YLR243W
  • cellular_component
  • biological_process
  • signal sequence binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nucleoid 8.8271E-4 11 26 2 6292
    mitochondrial nucleoid 8.8271E-4 11 26 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cellular amino acid metabolic process 2.6907E-4 11 199 4 6292
    cellular amine metabolic process 4.0941E-4 11 222 4 6292
    amine metabolic process 5.7795E-4 11 243 4 6292
    cellular amino acid and derivative metabolic process 5.7795E-4 11 243 4 6292
    cellular nitrogen compound biosynthetic process 6.1496E-4 11 247 4 6292
    cellular amino acid biosynthetic process 8.5971E-4 11 114 3 6292
    amine biosynthetic process 1.0475E-3 11 122 3 6292
    small molecule biosynthetic process 1.4476E-3 11 310 4 6292
    organic acid biosynthetic process 1.5287E-3 11 139 3 6292
    carboxylic acid biosynthetic process 1.5287E-3 11 139 3 6292
    carboxylic acid metabolic process 1.8897E-3 11 333 4 6292
    organic acid metabolic process 1.8897E-3 11 333 4 6292
    oxoacid metabolic process 1.8897E-3 11 333 4 6292
    cellular ketone metabolic process 2.1778E-3 11 346 4 6292
    aspartate family amino acid metabolic process 2.6406E-3 11 45 2 6292
    pyrimidine ribonucleoside triphosphate metabolic process 3.4937E-3 11 2 1 6292
    CTP biosynthetic process 3.4937E-3 11 2 1 6292
    CTP metabolic process 3.4937E-3 11 2 1 6292
    pyrimidine ribonucleotide metabolic process 3.4937E-3 11 2 1 6292
    pyrimidine ribonucleoside triphosphate biosynthetic process 3.4937E-3 11 2 1 6292
    pyrimidine ribonucleotide biosynthetic process 3.4937E-3 11 2 1 6292
    pyrimidine nucleoside triphosphate biosynthetic process 5.2364E-3 11 3 1 6292
    small molecule metabolic process 6.2697E-3 11 760 5 6292
    pyrimidine nucleoside triphosphate metabolic process 6.9763E-3 11 4 1 6292
    pyrimidine ribonucleoside metabolic process 6.9763E-3 11 4 1 6292
    isocitrate metabolic process 8.7135E-3 11 5 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2.3129E-4 11 73 3 6292
    oxidoreductase activity, acting on CH-OH group of donors 3.1486E-4 11 81 3 6292
    homoisocitrate dehydrogenase activity 1.7483E-3 11 1 1 6292
    ketol-acid reductoisomerase activity 1.7483E-3 11 1 1 6292
    CTP synthase activity 3.4937E-3 11 2 1 6292
    isocitrate dehydrogenase (NAD+) activity 3.4937E-3 11 2 1 6292
    inorganic phosphate transmembrane transporter activity 8.7135E-3 11 5 1 6292
    isocitrate dehydrogenase activity 8.7135E-3 11 5 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle