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Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+. Catalysis of the reaction: isocitrate + acceptor = 2-oxoglutarate + CO2 + reduced acceptor. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: isocitrate dehydrogenase (NAD+) activity
Acc: GO:0004449
Aspect: Molecular Function
Desc: Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+.
Synonyms:
  • NAD dependent isocitrate dehydrogenase activity
  • NAD isocitrate dehydrogenase activity
  • NAD isocitric dehydrogenase activity
  • NAD-linked isocitrate dehydrogenase activity
  • isocitrate dehydrogenase (NAD) activity
  • nicotinamide adenine dinucleotide isocitrate dehydrogenase activity
  • isocitrate:NAD+ oxidoreductase (decarboxylating)
  • NAD-specific isocitrate dehydrogenase activity
Proteins in PDR annotated with:
   This term: 39 [Search]
   Term or descendants: 39 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004449 - isocitrate dehydrogenase (NAD+) activity (interactive image map)

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