From Publication: | Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22. |
Notes: | From the published set of protein complexes (core proteins only) |
Complex Size: | 7 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
HOPS complex | 8.1421E-20 | 7 | 6 | 6 | 6292 |
vacuolar membrane | 2.0271E-10 | 7 | 113 | 6 | 6292 |
vacuolar part | 3.0802E-10 | 7 | 121 | 6 | 6292 |
fungal-type vacuole | 1.5651E-9 | 7 | 158 | 6 | 6292 |
lytic vacuole | 1.5651E-9 | 7 | 158 | 6 | 6292 |
storage vacuole | 1.5651E-9 | 7 | 158 | 6 | 6292 |
vacuole | 8.524E-9 | 7 | 209 | 6 | 6292 |
fungal-type vacuole membrane | 6.0093E-7 | 7 | 74 | 4 | 6292 |
membrane part | 8.472E-6 | 7 | 662 | 6 | 6292 |
organelle membrane | 1.1014E-5 | 7 | 692 | 6 | 6292 |
protein complex | 2.0393E-4 | 7 | 1137 | 6 | 6292 |
membrane | 2.7648E-4 | 7 | 1198 | 6 | 6292 |
macromolecular complex | 1.6651E-3 | 7 | 1635 | 6 | 6292 |
extrinsic to vacuolar membrane | 2.224E-3 | 7 | 2 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
vacuole fusion, non-autophagic | 2.4032E-14 | 7 | 27 | 6 | 6292 |
vacuole organization | 7.5849E-13 | 7 | 46 | 6 | 6292 |
membrane fusion | 8.0578E-12 | 7 | 67 | 6 | 6292 |
cellular membrane fusion | 8.0578E-12 | 7 | 67 | 6 | 6292 |
late endosome to vacuole transport | 1.0824E-11 | 7 | 24 | 5 | 6292 |
Golgi to endosome transport | 1.7656E-10 | 7 | 11 | 4 | 6292 |
endosome transport | 6.5693E-10 | 7 | 52 | 5 | 6292 |
cellular membrane organization | 6.147E-9 | 7 | 198 | 6 | 6292 |
membrane organization | 6.147E-9 | 7 | 198 | 6 | 6292 |
vacuolar transport | 3.8145E-8 | 7 | 115 | 5 | 6292 |
post-Golgi vesicle-mediated transport | 4.263E-7 | 7 | 68 | 4 | 6292 |
vesicle-mediated transport | 8.5922E-6 | 7 | 340 | 5 | 6292 |
Golgi vesicle transport | 1.6125E-5 | 7 | 168 | 4 | 6292 |
vesicle docking during exocytosis | 6.966E-5 | 7 | 12 | 2 | 6292 |
intracellular transport | 9.3173E-5 | 7 | 553 | 5 | 6292 |
transport | 9.4619E-5 | 7 | 997 | 6 | 6292 |
membrane docking | 9.5944E-5 | 7 | 14 | 2 | 6292 |
vesicle docking | 9.5944E-5 | 7 | 14 | 2 | 6292 |
establishment of localization | 1.009E-4 | 7 | 1008 | 6 | 6292 |
localization | 1.3542E-4 | 7 | 1060 | 6 | 6292 |
establishment of localization in cell | 1.3731E-4 | 7 | 599 | 5 | 6292 |
cellular localization | 1.9347E-4 | 7 | 643 | 5 | 6292 |
organelle organization | 1.9369E-4 | 7 | 1127 | 6 | 6292 |
exocytosis | 1.0729E-3 | 7 | 46 | 2 | 6292 |
cellular component organization | 1.3786E-3 | 7 | 1582 | 6 | 6292 |
secretion | 1.477E-3 | 7 | 54 | 2 | 6292 |
secretion by cell | 1.477E-3 | 7 | 54 | 2 | 6292 |
vacuolar protein processing | 5.552E-3 | 7 | 5 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
Rab guanyl-nucleotide exchange factor activity | 1.5882E-5 | 7 | 6 | 2 | 6292 |
Ras guanyl-nucleotide exchange factor activity | 1.6097E-4 | 7 | 18 | 2 | 6292 |
guanyl-nucleotide exchange factor activity | 7.3181E-4 | 7 | 38 | 2 | 6292 |
small GTPase regulator activity | 1.7614E-3 | 7 | 59 | 2 | 6292 |
GTPase regulator activity | 3.5412E-3 | 7 | 84 | 2 | 6292 |
nucleoside-triphosphatase regulator activity | 4.5092E-3 | 7 | 95 | 2 | 6292 |