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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
IWR1
  • nucleus
  • cytoplasm
  • DNA-directed RNA polymerase II, holoenzyme
  • transcription from RNA polymerase II promoter
  • meiosis
  • molecular_function
  • RPB11
  • DNA-directed RNA polymerase II, core complex
  • transcription from RNA polymerase II promoter
  • DNA-directed RNA polymerase activity
  • RPB2
  • mitochondrion
  • DNA-directed RNA polymerase II, core complex
  • transcription from RNA polymerase II promoter
  • DNA-directed RNA polymerase activity
  • RPB3
  • DNA-directed RNA polymerase II, core complex
  • transcription from RNA polymerase II promoter
  • DNA-directed RNA polymerase activity
  • RPB4
  • nucleus
  • cytoplasm
  • cytoplasmic mRNA processing body
  • DNA-directed RNA polymerase II, core complex
  • mRNA export from nucleus
  • telomere maintenance
  • transcription from RNA polymerase II promoter
  • nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
  • DNA-directed RNA polymerase activity
  • RPB7
  • DNA-directed RNA polymerase II, core complex
  • transcription from RNA polymerase II promoter
  • DNA-directed RNA polymerase activity
  • RPB9
  • DNA-directed RNA polymerase II, core complex
  • response to drug
  • transcription-coupled nucleotide-excision repair
  • telomere maintenance
  • transcription from RNA polymerase II promoter
  • response to DNA damage stimulus
  • DNA-directed RNA polymerase activity
  • TFG1
  • transcription factor TFIIF complex
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TFG2
  • transcription factor TFIIF complex
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA-directed RNA polymerase II, holoenzyme 1.7889E-19 9 56 9 6292
    DNA-directed RNA polymerase II, core complex 9.0058E-16 9 12 6 6292
    nucleoplasm part 1.7837E-13 9 245 9 6292
    nucleoplasm 3.5315E-13 9 264 9 6292
    RNA polymerase complex 7.1205E-13 9 31 6 6292
    nuclear DNA-directed RNA polymerase complex 7.1205E-13 9 31 6 6292
    DNA-directed RNA polymerase complex 7.1205E-13 9 31 6 6292
    nuclear lumen 4.8255E-11 9 453 9 6292
    organelle lumen 1.4638E-9 9 660 9 6292
    intracellular organelle lumen 1.4638E-9 9 660 9 6292
    membrane-enclosed lumen 2.4937E-9 9 700 9 6292
    nuclear part 1.5218E-7 9 1103 9 6292
    protein complex 2.0019E-7 9 1137 9 6292
    macromolecular complex 5.3146E-6 9 1635 9 6292
    transcription factor TFIIF complex 5.4528E-6 9 3 2 6292
    nucleus 3.9292E-5 9 2041 9 6292
    organelle part 1.0749E-4 9 2282 9 6292
    intracellular organelle part 1.0749E-4 9 2282 9 6292
    transcription factor complex 4.2943E-3 9 71 2 6292
    membrane-bounded organelle 9.9391E-3 9 3771 9 6292
    intracellular membrane-bounded organelle 9.9391E-3 9 3771 9 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    transcription from RNA polymerase II promoter 3.1026E-12 9 335 9 6292
    transcription, DNA-dependent 1.2481E-10 9 503 9 6292
    RNA biosynthetic process 1.3652E-10 9 508 9 6292
    transcription 2.8998E-10 9 552 9 6292
    RNA metabolic process 4.101E-8 9 954 9 6292
    cellular macromolecule biosynthetic process 2.9528E-7 9 1187 9 6292
    macromolecule biosynthetic process 2.9981E-7 9 1189 9 6292
    gene expression 5.9596E-7 9 1283 9 6292
    nucleic acid metabolic process 1.4425E-6 9 1415 9 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.6017E-6 9 1566 9 6292
    cellular biosynthetic process 3.6225E-6 9 1567 9 6292
    biosynthetic process 4.4215E-6 9 1602 9 6292
    cellular nitrogen compound metabolic process 1.0872E-5 9 1770 9 6292
    nitrogen compound metabolic process 1.2092E-5 9 1791 9 6292
    cellular macromolecule metabolic process 1.0877E-4 9 2285 9 6292
    macromolecule metabolic process 1.3953E-4 9 2349 9 6292
    primary metabolic process 9.2081E-4 9 2896 9 6292
    cellular metabolic process 1.3966E-3 9 3033 9 6292
    transcription initiation from RNA polymerase II promoter 1.9017E-3 9 47 2 6292
    metabolic process 2.004E-3 9 3157 9 6292
    transcription-coupled nucleotide-excision repair 2.859E-3 9 2 1 6292
    transcription initiation 2.8843E-3 9 58 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RNA polymerase activity 1.299E-12 9 34 6 6292
    DNA-directed RNA polymerase activity 1.299E-12 9 34 6 6292
    nucleotidyltransferase activity 2.607E-8 9 168 6 6292
    transferase activity, transferring phosphorus-containing groups 6.0378E-6 9 420 6 6292
    transferase activity 2.4256E-4 9 797 6 6292
    general RNA polymerase II transcription factor activity 3.502E-3 9 64 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle