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View Protein Complex Details

Complex Overview

From Publication: Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes: MIPS hand-curated complex set. MIPS complex ID: 500.60.10
Complex Size: 44 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
IMG1
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • IMG2
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • MNP1
  • mitochondrion
  • mitochondrial ribosome
  • aerobic respiration
  • translation
  • structural constituent of ribosome
  • MRP20
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRP49
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRP7
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • peptidyltransferase activity
  • MRPL1
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • aerobic respiration
  • translation
  • structural constituent of ribosome
  • MRPL10
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL11
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL13
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL15
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL16
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • peptidyltransferase activity
  • MRPL17
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL19
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL20
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • mitochondrial genome maintenance
  • translation
  • structural constituent of ribosome
  • MRPL22
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • aerobic respiration
  • translation
  • structural constituent of ribosome
  • MRPL23
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • MRPL24
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL25
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL27
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL28
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL3
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL31
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL32
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL33
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL35
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL36
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL37
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL38
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • MRPL39
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL4
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL40
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL44
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • MRPL49
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL50
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL51
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • aerobic respiration
  • translation
  • structural constituent of ribosome
  • MRPL6
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL7
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL8
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • mitochondrial genome maintenance
  • translation
  • structural constituent of ribosome
  • MRPL9
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • peptidyltransferase activity
  • RML2
  • mitochondrial large ribosomal subunit
  • fatty acid metabolic process
  • translation
  • structural constituent of ribosome
  • RTC6
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • YDR115W
  • mitochondrial large ribosomal subunit
  • telomere maintenance
  • aerobic respiration
  • structural constituent of ribosome
  • YML6
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    organellar large ribosomal subunit 1.3746E-101 44 50 43 6292
    mitochondrial large ribosomal subunit 1.3746E-101 44 50 43 6292
    organellar ribosome 2.2393E-87 44 90 44 6292
    mitochondrial ribosome 2.2393E-87 44 90 44 6292
    large ribosomal subunit 9.8265E-79 44 110 43 6292
    mitochondrial matrix 1.4678E-71 44 176 44 6292
    mitochondrial lumen 1.4678E-71 44 176 44 6292
    ribosomal subunit 2.0066E-67 44 183 43 6292
    ribosome 5.9004E-61 44 290 44 6292
    mitochondrial part 6.319E-51 44 475 44 6292
    ribonucleoprotein complex 2.3893E-49 44 514 44 6292
    organelle lumen 2.1981E-44 44 660 44 6292
    intracellular organelle lumen 2.1981E-44 44 660 44 6292
    membrane-enclosed lumen 3.1885E-43 44 700 44 6292
    non-membrane-bounded organelle 4.8275E-37 44 959 44 6292
    intracellular non-membrane-bounded organelle 4.8275E-37 44 959 44 6292
    mitochondrion 6.3017E-34 44 1125 44 6292
    macromolecular complex 1.1481E-26 44 1635 44 6292
    organelle part 3.1874E-20 44 2282 44 6292
    intracellular organelle part 3.1874E-20 44 2282 44 6292
    cytoplasmic part 1.329E-18 44 2482 44 6292
    cytoplasm 1.0554E-11 44 3552 44 6292
    membrane-bounded organelle 1.4909E-10 44 3771 44 6292
    intracellular membrane-bounded organelle 1.4909E-10 44 3771 44 6292
    intracellular organelle 4.3611E-9 44 4070 44 6292
    organelle 4.4087E-9 44 4071 44 6292
    intracellular part 2.2467E-5 44 4938 44 6292
    intracellular 3.1248E-5 44 4975 44 6292
    cell part 1.1406E-3 44 5397 44 6292
    cell 1.1594E-3 44 5399 44 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 9.62E-53 44 376 43 6292
    cellular protein metabolic process 1.757E-32 44 1074 43 6292
    protein metabolic process 2.0336E-31 44 1136 43 6292
    cellular macromolecule biosynthetic process 1.3784E-30 44 1187 43 6292
    macromolecule biosynthetic process 1.4833E-30 44 1189 43 6292
    gene expression 4.0647E-29 44 1283 43 6292
    cellular biosynthetic process 2.3723E-25 44 1567 43 6292
    biosynthetic process 6.1678E-25 44 1602 43 6292
    cellular macromolecule metabolic process 3.379E-20 44 2285 44 6292
    macromolecule metabolic process 1.1524E-19 44 2349 44 6292
    primary metabolic process 1.2454E-15 44 2896 44 6292
    cellular metabolic process 9.661E-15 44 3033 44 6292
    metabolic process 5.7028E-14 44 3157 44 6292
    cellular process 1.7788E-7 44 4426 44 6292
    aerobic respiration 2.5658E-4 44 83 5 6292
    cellular respiration 5.2974E-4 44 97 5 6292
    ribosomal large subunit assembly 2.8261E-3 44 41 3 6292
    energy derivation by oxidation of organic compounds 3.5932E-3 44 149 5 6292
    ribosomal subunit assembly 6.4982E-3 44 55 3 6292
    ribosome assembly 9.8798E-3 44 64 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.5542E-67 44 212 44 6292
    structural molecule activity 9.5535E-58 44 339 44 6292
    peptidyltransferase activity 3.1916E-7 44 3 3 6292
    transferase activity, transferring amino-acyl groups 3.1605E-6 44 5 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle