YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CTI6
  • nucleus
  • positive regulation of transcription
  • histone deacetylation
  • histone deacetylase activity
  • transcription factor binding
  • PHO23
  • nucleus
  • histone deacetylase complex
  • chromatin modification
  • histone deacetylation
  • histone deacetylase activity
  • RPD3
  • histone deacetylase complex
  • negative regulation of transcription from RNA polymerase II promoter
  • chromatin silencing at rDNA
  • loss of chromatin silencing involved in replicative cell aging
  • protein amino acid deacetylation
  • chromatin silencing
  • double-strand break repair via nonhomologous end joining
  • chromatin organization
  • histone deacetylation
  • chromatin silencing at silent mating-type cassette
  • positive regulation of transcription from RNA polymerase II promoter
  • chromatin silencing at telomere
  • mitotic recombination
  • transcription coactivator activity
  • histone deacetylase activity
  • transcription corepressor activity
  • RXT2
  • nucleus
  • negative regulation of transcription from RNA polymerase II promoter
  • conjugation with cellular fusion
  • invasive growth in response to glucose limitation
  • histone deacetylation
  • histone deacetylase activity
  • RXT3
  • nucleus
  • chromatin silencing
  • histone deacetylation
  • histone deacetylase activity
  • SAP30
  • histone deacetylase complex
  • chromatin silencing at rDNA
  • telomere maintenance
  • histone deacetylation
  • chromatin silencing at silent mating-type cassette
  • chromatin silencing at telomere
  • histone deacetylase activity
  • SDS3
  • nucleus
  • Rpd3L-Expanded complex
  • Rpd3L complex
  • chromatin silencing
  • histone deacetylation
  • histone deacetylase activity
  • SIN3
  • Sin3 complex
  • histone deacetylase complex
  • negative regulation of transcription from RNA polymerase II promoter
  • chromatin silencing at rDNA
  • telomere maintenance
  • double-strand break repair via nonhomologous end joining
  • histone deacetylation
  • chromatin silencing at silent mating-type cassette
  • positive regulation of transcription from RNA polymerase II promoter
  • chromatin silencing at telomere
  • transcription coactivator activity
  • histone deacetylase activity
  • transcription corepressor activity
  • UME1
  • nucleus
  • regulation of meiosis
  • histone deacetylation
  • histone deacetylase activity
  • transcription corepressor activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    histone deacetylase complex 5.1182E-11 9 23 5 6292
    chromatin remodeling complex 1.0447E-7 9 99 5 6292
    nucleoplasm part 9.5284E-6 9 245 5 6292
    nucleoplasm 1.374E-5 9 264 5 6292
    Sin3-type complex 1.8149E-5 9 5 2 6292
    nucleus 3.9292E-5 9 2041 9 6292
    nuclear lumen 1.8703E-4 9 453 5 6292
    organelle lumen 1.0993E-3 9 660 5 6292
    intracellular organelle lumen 1.0993E-3 9 660 5 6292
    Rpd3L complex 1.4304E-3 9 1 1 6292
    Rpd3L-Expanded complex 1.4304E-3 9 1 1 6292
    membrane-enclosed lumen 1.4429E-3 9 700 5 6292
    nuclear chromatin 4.5346E-3 9 73 2 6292
    chromatin 5.0339E-3 9 77 2 6292
    Sin3 complex 5.7106E-3 9 4 1 6292
    membrane-bounded organelle 9.9391E-3 9 3771 9 6292
    intracellular membrane-bounded organelle 9.9391E-3 9 3771 9 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    histone deacetylation 1.1067E-22 9 27 9 6292
    protein amino acid deacetylation 2.3648E-22 9 29 9 6292
    covalent chromatin modification 1.3491E-17 9 88 9 6292
    histone modification 1.3491E-17 9 88 9 6292
    chromatin modification 5.5782E-15 9 168 9 6292
    chromatin organization 3.1823E-14 9 203 9 6292
    post-translational protein modification 5.5368E-12 9 357 9 6292
    protein modification process 1.1609E-10 9 499 9 6292
    chromosome organization 3.0459E-10 9 555 9 6292
    macromolecule modification 3.8175E-10 9 569 9 6292
    negative regulation of transcription, DNA-dependent 1.7334E-8 9 157 6 6292
    negative regulation of RNA metabolic process 1.8011E-8 9 158 6 6292
    negative regulation of transcription 2.2548E-8 9 164 6 6292
    negative regulation of gene expression 2.2548E-8 9 164 6 6292
    negative regulation of macromolecule biosynthetic process 3.3329E-8 9 175 6 6292
    negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.948E-8 9 180 6 6292
    negative regulation of nitrogen compound metabolic process 3.948E-8 9 180 6 6292
    negative regulation of biosynthetic process 5.2922E-8 9 189 6 6292
    negative regulation of cellular biosynthetic process 5.2922E-8 9 189 6 6292
    negative regulation of macromolecule metabolic process 5.8167E-8 9 192 6 6292
    negative regulation of cellular metabolic process 9.6707E-8 9 209 6 6292
    regulation of transcription 9.6795E-8 9 384 7 6292
    negative regulation of metabolic process 9.9509E-8 9 210 6 6292
    negative regulation of gene expression, epigenetic 1.099E-7 9 100 5 6292
    gene silencing 1.099E-7 9 100 5 6292
    regulation of gene expression, epigenetic 1.099E-7 9 100 5 6292
    chromatin silencing 1.099E-7 9 100 5 6292
    cellular protein metabolic process 1.1963E-7 9 1074 9 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.6585E-7 9 415 7 6292
    regulation of nitrogen compound metabolic process 1.6863E-7 9 416 7 6292
    organelle organization 1.8484E-7 9 1127 9 6292
    protein metabolic process 1.9861E-7 9 1136 9 6292
    regulation of gene expression 2.6886E-7 9 445 7 6292
    negative regulation of cellular process 2.8178E-7 9 250 6 6292
    negative regulation of biological process 3.0252E-7 9 253 6 6292
    regulation of macromolecule biosynthetic process 3.1831E-7 9 456 7 6292
    regulation of cellular biosynthetic process 4.0393E-7 9 472 7 6292
    regulation of biosynthetic process 4.0988E-7 9 473 7 6292
    regulation of macromolecule metabolic process 5.0842E-7 9 488 7 6292
    regulation of cellular process 5.0877E-7 9 796 8 6292
    regulation of biological process 6.6868E-7 9 824 8 6292
    regulation of primary metabolic process 7.2713E-7 9 514 7 6292
    regulation of cellular metabolic process 9.7027E-7 9 536 7 6292
    regulation of metabolic process 1.1157E-6 9 547 7 6292
    transcription 1.1877E-6 9 552 7 6292
    chromatin silencing at rDNA 1.6342E-6 9 18 3 6292
    regulation of transcription, DNA-dependent 2.3635E-6 9 358 6 6292
    regulation of RNA metabolic process 2.5646E-6 9 363 6 6292
    cellular component organization 3.9477E-6 9 1582 9 6292
    chromatin silencing at silent mating-type cassette 1.081E-5 9 33 3 6292
    biological regulation 1.3981E-5 9 1213 8 6292
    transcription, DNA-dependent 1.7286E-5 9 503 6 6292
    RNA biosynthetic process 1.8308E-5 9 508 6 6292
    chromatin silencing at telomere 5.1163E-5 9 55 3 6292
    negative regulation of transcription from RNA polymerase II promoter 6.6496E-5 9 60 3 6292
    cellular macromolecule metabolic process 1.0877E-4 9 2285 9 6292
    macromolecule metabolic process 1.3953E-4 9 2349 9 6292
    cellular macromolecule biosynthetic process 2.1089E-4 9 1187 7 6292
    macromolecule biosynthetic process 2.1326E-4 9 1189 7 6292
    gene expression 3.5247E-4 9 1283 7 6292
    positive regulation of transcription 4.266E-4 9 112 3 6292
    positive regulation of gene expression 4.266E-4 9 112 3 6292
    positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.9743E-4 9 118 3 6292
    positive regulation of nitrogen compound metabolic process 4.9743E-4 9 118 3 6292
    positive regulation of macromolecule biosynthetic process 4.9743E-4 9 118 3 6292
    positive regulation of biosynthetic process 5.3553E-4 9 121 3 6292
    positive regulation of cellular biosynthetic process 5.3553E-4 9 121 3 6292
    double-strand break repair via nonhomologous end joining 5.3645E-4 9 25 2 6292
    positive regulation of macromolecule metabolic process 6.0312E-4 9 126 3 6292
    positive regulation of metabolic process 6.4619E-4 9 129 3 6292
    positive regulation of cellular metabolic process 6.4619E-4 9 129 3 6292
    RNA metabolic process 6.6568E-4 9 954 6 6292
    nucleic acid metabolic process 6.6981E-4 9 1415 7 6292
    positive regulation of cellular process 7.5429E-4 9 136 3 6292
    positive regulation of biological process 7.7062E-4 9 137 3 6292
    primary metabolic process 9.2081E-4 9 2896 9 6292
    non-recombinational repair 9.9648E-4 9 34 2 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.294E-3 9 1566 7 6292
    cellular biosynthetic process 1.2993E-3 9 1567 7 6292
    cellular metabolic process 1.3966E-3 9 3033 9 6292
    biosynthetic process 1.4983E-3 9 1602 7 6292
    metabolic process 2.004E-3 9 3157 9 6292
    double-strand break repair 2.7869E-3 9 57 2 6292
    cellular nitrogen compound metabolic process 2.8378E-3 9 1770 7 6292
    nitrogen compound metabolic process 3.0588E-3 9 1791 7 6292
    regulation of transcription from RNA polymerase II promoter 3.3545E-3 9 228 3 6292
    positive regulation of transcription from RNA polymerase II promoter 5.9661E-3 9 84 2 6292
    positive regulation of transcription, DNA-dependent 8.8641E-3 9 103 2 6292
    positive regulation of RNA metabolic process 9.541E-3 9 107 2 6292
    transcription from RNA polymerase II promoter 9.881E-3 9 335 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    histone deacetylase activity 6.6232E-22 9 32 9 6292
    protein deacetylase activity 6.6232E-22 9 32 9 6292
    deacetylase activity 1.6673E-21 9 35 9 6292
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3.9601E-20 9 48 9 6292
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 5.4759E-18 9 80 9 6292
    hydrolase activity 2.7029E-8 9 911 9 6292
    transcription factor binding 2.3248E-7 9 43 4 6292
    transcription corepressor activity 1.1231E-6 9 16 3 6292
    transcription cofactor activity 1.9476E-5 9 40 3 6292
    transcription repressor activity 2.6033E-5 9 44 3 6292
    catalytic activity 6.2813E-5 9 2150 9 6292
    transcription coactivator activity 3.7663E-4 9 21 2 6292
    transcription activator activity 3.186E-3 9 61 2 6292
    protein binding 7.4954E-3 9 612 4 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle