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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 7 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ASK1
  • condensed nuclear chromosome, centromeric region
  • DASH complex
  • spindle
  • condensed nuclear chromosome kinetochore
  • mitotic spindle organization in nucleus
  • regulation of microtubule polymerization or depolymerization
  • structural constituent of cytoskeleton
  • DAD1
  • DASH complex
  • spindle
  • condensed nuclear chromosome kinetochore
  • mitotic spindle organization in nucleus
  • regulation of microtubule polymerization or depolymerization
  • structural constituent of cytoskeleton
  • DAD2
  • DASH complex
  • spindle
  • condensed nuclear chromosome kinetochore
  • mitotic spindle organization in nucleus
  • regulation of microtubule polymerization or depolymerization
  • structural constituent of cytoskeleton
  • DAM1
  • spindle midzone
  • kinetochore microtubule
  • DASH complex
  • spindle
  • condensed nuclear chromosome kinetochore
  • mitotic spindle organization in nucleus
  • regulation of microtubule polymerization or depolymerization
  • structural constituent of cytoskeleton
  • DUO1
  • spindle microtubule
  • DASH complex
  • spindle pole body
  • spindle
  • condensed nuclear chromosome kinetochore
  • mitotic spindle organization in nucleus
  • regulation of microtubule polymerization or depolymerization
  • structural constituent of cytoskeleton
  • SPC19
  • spindle microtubule
  • DASH complex
  • spindle pole body
  • spindle
  • condensed nuclear chromosome kinetochore
  • microtubule nucleation
  • mitotic spindle organization in nucleus
  • regulation of microtubule polymerization or depolymerization
  • structural constituent of cytoskeleton
  • SPC34
  • spindle microtubule
  • DASH complex
  • spindle pole body
  • spindle
  • condensed nuclear chromosome kinetochore
  • microtubule nucleation
  • mitotic spindle organization in nucleus
  • regulation of microtubule polymerization or depolymerization
  • structural constituent of cytoskeleton
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DASH complex 1.0259E-20 7 12 7 6292
    condensed nuclear chromosome kinetochore 1.1126E-15 7 49 7 6292
    condensed chromosome kinetochore 1.1126E-15 7 49 7 6292
    condensed chromosome, centromeric region 2.6285E-15 7 55 7 6292
    condensed nuclear chromosome, centromeric region 2.6285E-15 7 55 7 6292
    kinetochore 5.0024E-15 7 60 7 6292
    chromosome, centromeric region 1.1264E-14 7 67 7 6292
    condensed nuclear chromosome 6.9597E-14 7 86 7 6292
    spindle 8.9247E-14 7 89 7 6292
    condensed chromosome 1.3258E-13 7 94 7 6292
    microtubule cytoskeleton 3.1566E-13 7 106 7 6292
    nuclear chromosome part 2.0542E-11 7 190 7 6292
    cytoskeletal part 3.065E-11 7 201 7 6292
    cytoskeleton 5.1104E-11 7 216 7 6292
    nuclear chromosome 7.5004E-11 7 228 7 6292
    chromosomal part 9.8703E-11 7 237 7 6292
    chromosome 2.7582E-10 7 274 7 6292
    spindle microtubule 1.2705E-9 7 17 4 6292
    microtubule 1.6706E-8 7 31 4 6292
    non-membrane-bounded organelle 1.8755E-6 7 959 7 6292
    intracellular non-membrane-bounded organelle 1.8755E-6 7 959 7 6292
    nuclear part 5.0081E-6 7 1103 7 6292
    protein complex 6.1975E-6 7 1137 7 6292
    microtubule organizing center 3.2546E-5 7 63 3 6292
    spindle pole body 3.2546E-5 7 63 3 6292
    spindle pole 4.0976E-5 7 68 3 6292
    macromolecular complex 7.9244E-5 7 1635 7 6292
    nucleus 3.7528E-4 7 2041 7 6292
    organelle part 8.2061E-4 7 2282 7 6292
    intracellular organelle part 8.2061E-4 7 2282 7 6292
    kinetochore microtubule 7.7654E-3 7 7 1 6292
    spindle midzone 7.7654E-3 7 7 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    regulation of microtubule cytoskeleton organization 2.519E-19 7 17 7 6292
    regulation of microtubule polymerization or depolymerization 2.519E-19 7 17 7 6292
    regulation of microtubule-based process 2.519E-19 7 17 7 6292
    microtubule polymerization or depolymerization 4.1221E-19 7 18 7 6292
    regulation of cytoskeleton organization 1.0041E-18 7 20 7 6292
    mitotic spindle organization in nucleus 8.5203E-18 7 26 7 6292
    mitotic spindle organization 9.5369E-16 7 48 7 6292
    spindle organization 1.1126E-15 7 49 7 6292
    regulation of organelle organization 1.7329E-15 7 52 7 6292
    regulation of cellular component organization 2.5709E-14 7 75 7 6292
    microtubule cytoskeleton organization 1.6639E-13 7 97 7 6292
    microtubule-based process 4.3992E-13 7 111 7 6292
    cytoskeleton organization 8.2292E-11 7 231 7 6292
    mitotic cell cycle 1.6582E-10 7 255 7 6292
    M phase 4.5405E-10 7 294 7 6292
    cell cycle phase 2.5814E-9 7 376 7 6292
    cell cycle process 1.6696E-8 7 490 7 6292
    cell cycle 2.7139E-8 7 525 7 6292
    regulation of cellular process 5.0679E-7 7 796 7 6292
    regulation of biological process 6.4613E-7 7 824 7 6292
    organelle organization 5.8249E-6 7 1127 7 6292
    biological regulation 9.7594E-6 7 1213 7 6292
    cellular component organization 6.2893E-5 7 1582 7 6292
    microtubule nucleation 2.6548E-4 7 23 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of cytoskeleton 1.9966E-15 7 53 7 6292
    structural molecule activity 1.2424E-9 7 339 7 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle