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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
MOT1
  • mitochondrion
  • nuclear chromosome
  • nuclear outer membrane
  • transcription of nuclear rRNA large RNA polymerase I transcript
  • regulation of RNA polymerase II transcriptional preinitiation complex assembly
  • regulation of transcription from RNA polymerase II promoter
  • ATPase activity
  • rDNA binding
  • TATA-binding protein binding
  • NPL6
  • nucleus
  • RSC complex
  • chromatin remodeling
  • protein import into nucleus
  • ATP-dependent chromatin remodeling
  • telomere maintenance
  • response to DNA damage stimulus
  • DNA-dependent ATPase activity
  • RSC2
  • RSC complex
  • sister chromatid cohesion
  • ATP-dependent chromatin remodeling
  • telomere maintenance
  • double-strand break repair via nonhomologous end joining
  • DNA-dependent ATPase activity
  • RSC3
  • nucleus
  • RSC complex
  • ATP-dependent chromatin remodeling
  • regulation of transcription, DNA-dependent
  • DNA binding
  • DNA-dependent ATPase activity
  • RSC4
  • RSC complex
  • ATP-dependent chromatin remodeling
  • DNA-dependent ATPase activity
  • RSC58
  • RSC complex
  • chromatin remodeling
  • molecular_function
  • RSC8
  • nucleus
  • RSC complex
  • ATP-dependent chromatin remodeling
  • double-strand break repair via nonhomologous end joining
  • DNA-dependent ATPase activity
  • STH1
  • RSC complex
  • cytoskeleton organization
  • ATP-dependent chromatin remodeling
  • chromosome segregation
  • chromatin remodeling at centromere
  • meiosis
  • double-strand break repair
  • ATPase activity
  • DNA-dependent ATPase activity
  • VPS1
  • membrane fraction
  • peroxisome
  • cytoplasm
  • mitochondrial outer membrane
  • protein retention in Golgi apparatus
  • peroxisome organization
  • vacuolar transport
  • protein targeting to vacuole
  • actin cytoskeleton organization
  • GTPase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RSC complex 3.6017E-17 9 20 7 6292
    chromatin remodeling complex 6.7651E-12 9 99 7 6292
    nuclear part 6.6425E-6 9 1103 8 6292
    organelle part 1.0749E-4 9 2282 9 6292
    intracellular organelle part 1.0749E-4 9 2282 9 6292
    protein complex 1.5852E-4 9 1137 7 6292
    nucleus 7.7873E-4 9 2041 8 6292
    macromolecular complex 1.7084E-3 9 1635 7 6292
    membrane-bounded organelle 9.9391E-3 9 3771 9 6292
    intracellular membrane-bounded organelle 9.9391E-3 9 3771 9 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ATP-dependent chromatin remodeling 2.2311E-13 9 26 6 6292
    chromatin remodeling 4.444E-13 9 68 7 6292
    chromatin modification 2.9424E-10 9 168 7 6292
    chromatin organization 1.1201E-9 9 203 7 6292
    chromosome organization 1.2328E-6 9 555 7 6292
    cellular component organization 3.9477E-6 9 1582 9 6292
    organelle organization 7.8634E-6 9 1127 8 6292
    double-strand break repair 5.698E-5 9 57 3 6292
    response to DNA damage stimulus 2.0954E-4 9 236 4 6292
    cellular response to stress 4.634E-4 9 290 4 6292
    double-strand break repair via nonhomologous end joining 5.3645E-4 9 25 2 6292
    non-recombinational repair 9.9648E-4 9 34 2 6292
    cellular response to stimulus 1.2811E-3 9 379 4 6292
    RNA polymerase II transcriptional preinitiation complex assembly 1.4304E-3 9 1 1 6292
    regulation of RNA polymerase II transcriptional preinitiation complex assembly 1.4304E-3 9 1 1 6292
    transcription of nuclear rRNA large RNA polymerase I transcript 1.4304E-3 9 1 1 6292
    regulation of transcription initiation from RNA polymerase II promoter 1.4304E-3 9 1 1 6292
    transcriptional preinitiation complex assembly 1.4304E-3 9 1 1 6292
    DNA repair 2.0512E-3 9 192 3 6292
    chromatin remodeling at centromere 2.859E-3 9 2 1 6292
    response to stress 3.515E-3 9 497 4 6292
    rRNA transcription 4.2857E-3 9 3 1 6292
    nucleic acid metabolic process 5.7023E-3 9 1415 6 6292
    DNA metabolic process 6.3704E-3 9 585 4 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 9.7168E-3 9 1566 6 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DNA-dependent ATPase activity 2.776E-11 9 55 6 6292
    nucleoside-triphosphatase activity 4.426E-10 9 329 8 6292
    hydrolase activity, acting on acid anhydrides 7.7918E-10 9 353 8 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 7.7918E-10 9 353 8 6292
    pyrophosphatase activity 7.7918E-10 9 353 8 6292
    ATPase activity 1.4707E-9 9 211 7 6292
    ATPase activity, coupled 1.2641E-8 9 149 6 6292
    hydrolase activity 1.4767E-6 9 911 8 6292
    catalytic activity 1.156E-3 9 2150 8 6292
    TATA-binding protein binding 2.859E-3 9 2 1 6292
    rDNA binding 9.9746E-3 9 7 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle