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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 8 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CBF5
  • box H/ACA snoRNP complex
  • nuclear outer membrane
  • nucleolus
  • rRNA pseudouridine synthesis
  • ribosome biogenesis
  • pseudouridylate synthase activity
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • NOP56
  • box C/D snoRNP complex
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • RRP12
  • nucleus
  • ribosome
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 4.9972E-11 8 72 6 6292
    nuclear outer membrane 2.3012E-8 8 86 5 6292
    nucleolus 3.5107E-8 8 211 6 6292
    nuclear membrane 4.2397E-8 8 97 5 6292
    ribonucleoprotein complex 1.7384E-7 8 514 7 6292
    outer membrane 8.9582E-7 8 178 5 6292
    organelle outer membrane 8.9582E-7 8 178 5 6292
    nuclear envelope 1.5606E-6 8 199 5 6292
    nuclear lumen 3.3344E-6 8 453 6 6292
    nuclear membrane-endoplasmic reticulum network 3.3401E-6 8 232 5 6292
    non-membrane-bounded organelle 1.3016E-5 8 959 7 6292
    intracellular non-membrane-bounded organelle 1.3016E-5 8 959 7 6292
    organelle lumen 3.0323E-5 8 660 6 6292
    intracellular organelle lumen 3.0323E-5 8 660 6 6292
    membrane-enclosed lumen 4.2703E-5 8 700 6 6292
    endomembrane system 4.7184E-5 8 398 5 6292
    envelope 1.4914E-4 8 505 5 6292
    organelle envelope 1.4914E-4 8 505 5 6292
    macromolecular complex 4.9027E-4 8 1635 7 6292
    membrane part 5.4233E-4 8 662 5 6292
    nuclear part 5.8147E-4 8 1103 6 6292
    organelle membrane 6.6856E-4 8 692 5 6292
    nucleolar part 1.3628E-3 8 45 2 6292
    nucleus 2.1521E-3 8 2041 7 6292
    box C/D snoRNP complex 2.5415E-3 8 2 1 6292
    box H/ACA snoRNP complex 2.5415E-3 8 2 1 6292
    membrane 8.3295E-3 8 1198 5 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    rRNA processing 9.6299E-12 8 128 7 6292
    maturation of SSU-rRNA 1.4463E-11 8 59 6 6292
    rRNA metabolic process 1.5649E-11 8 137 7 6292
    ribosome biogenesis 7.7416E-11 8 346 8 6292
    ribonucleoprotein complex biogenesis 1.4517E-10 8 374 8 6292
    ncRNA processing 3.8413E-10 8 215 7 6292
    ncRNA metabolic process 1.3532E-9 8 257 7 6292
    RNA processing 2.1096E-8 8 380 7 6292
    cellular component biogenesis 2.1131E-8 8 694 8 6292
    rRNA modification 1.0914E-6 8 18 3 6292
    RNA metabolic process 1.2557E-5 8 954 7 6292
    RNA modification 7.0971E-5 8 70 3 6292
    gene expression 9.518E-5 8 1283 7 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1.0958E-4 8 13 2 6292
    nucleic acid metabolic process 1.8497E-4 8 1415 7 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.6683E-4 8 1566 7 6292
    cellular nitrogen compound metabolic process 8.3438E-4 8 1770 7 6292
    nitrogen compound metabolic process 9.0281E-4 8 1791 7 6292
    ncRNA 5'-end processing 3.8101E-3 8 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.8101E-3 8 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.8101E-3 8 3 1 6292
    rRNA 5'-end processing 3.8101E-3 8 3 1 6292
    RNA 5'-end processing 3.8101E-3 8 3 1 6292
    cellular macromolecule metabolic process 4.5244E-3 8 2285 7 6292
    rRNA pseudouridine synthesis 5.0773E-3 8 4 1 6292
    maturation of 5.8S rRNA 5.0773E-3 8 4 1 6292
    cleavage involved in rRNA processing 5.0773E-3 8 4 1 6292
    maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.0773E-3 8 4 1 6292
    endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.0773E-3 8 4 1 6292
    endonucleolytic cleavage involved in rRNA processing 5.0773E-3 8 4 1 6292
    endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.0773E-3 8 4 1 6292
    macromolecule metabolic process 5.4192E-3 8 2349 7 6292
    snoRNA 3'-end processing 6.3431E-3 8 5 1 6292
    snoRNA processing 8.8705E-3 8 7 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 5.9655E-6 8 31 3 6292
    pseudouridylate synthase activity 6.3431E-3 8 5 1 6292
    RNA binding 8.8446E-3 8 367 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle