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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ECM16
  • mitochondrion
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • RNA helicase activity
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • NOP14
  • mitochondrion
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • snoRNA binding
  • NOP56
  • box C/D snoRNP complex
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS13
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • RRP12
  • nucleus
  • ribosome
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    90S preribosome 4.5585E-9 9 17 4 6292
    ribonucleoprotein complex 1.576E-8 9 514 8 6292
    non-membrane-bounded organelle 4.2994E-8 9 959 9 6292
    intracellular non-membrane-bounded organelle 4.2994E-8 9 959 9 6292
    preribosome 8.7868E-8 9 34 4 6292
    small nucleolar ribonucleoprotein complex 1.9024E-6 9 72 4 6292
    nucleolus 4.5683E-6 9 211 5 6292
    cytosolic small ribosomal subunit 1.6654E-5 9 38 3 6292
    small ribosomal subunit 1.1973E-4 9 73 3 6292
    macromolecular complex 1.4222E-4 9 1635 8 6292
    nuclear lumen 1.8703E-4 9 453 5 6292
    nuclear outer membrane 1.9518E-4 9 86 3 6292
    nuclear membrane 2.7897E-4 9 97 3 6292
    cytosolic ribosome 3.1441E-4 9 101 3 6292
    ribosome 4.634E-4 9 290 4 6292
    cytosolic part 5.4863E-4 9 122 3 6292
    organelle lumen 1.0993E-3 9 660 5 6292
    intracellular organelle lumen 1.0993E-3 9 660 5 6292
    membrane-enclosed lumen 1.4429E-3 9 700 5 6292
    outer membrane 1.6491E-3 9 178 3 6292
    organelle outer membrane 1.6491E-3 9 178 3 6292
    nucleolar part 1.7442E-3 9 45 2 6292
    ribosomal subunit 1.7864E-3 9 183 3 6292
    intracellular organelle part 1.8134E-3 9 2282 8 6292
    organelle part 1.8134E-3 9 2282 8 6292
    nuclear envelope 2.2736E-3 9 199 3 6292
    box C/D snoRNP complex 2.859E-3 9 2 1 6292
    Noc4p-Nop14p complex 2.859E-3 9 2 1 6292
    nuclear membrane-endoplasmic reticulum network 3.5247E-3 9 232 3 6292
    cytosol 6.2396E-3 9 284 3 6292
    Noc complex 7.1338E-3 9 5 1 6292
    preribosome, small subunit precursor 8.5551E-3 9 6 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    maturation of SSU-rRNA 1.5678E-13 9 59 7 6292
    rRNA processing 4.2605E-11 9 128 7 6292
    rRNA metabolic process 6.9145E-11 9 137 7 6292
    ribosome biogenesis 6.6343E-10 9 346 8 6292
    ribonucleoprotein complex biogenesis 1.2388E-9 9 374 8 6292
    ncRNA processing 1.6785E-9 9 215 7 6292
    ncRNA metabolic process 5.8777E-9 9 257 7 6292
    RNA processing 9.0007E-8 9 380 7 6292
    cellular component biogenesis 1.7172E-7 9 694 8 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 5.7481E-7 9 13 3 6292
    gene expression 2.1668E-5 9 1283 8 6292
    RNA metabolic process 4.9072E-5 9 954 7 6292
    ribosomal small subunit biogenesis 5.8072E-4 9 26 2 6292
    nucleic acid metabolic process 6.6981E-4 9 1415 7 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.294E-3 9 1566 7 6292
    cellular macromolecule metabolic process 1.8315E-3 9 2285 8 6292
    macromolecule metabolic process 2.2547E-3 9 2349 8 6292
    regulation of translation 2.7869E-3 9 57 2 6292
    cellular nitrogen compound metabolic process 2.8378E-3 9 1770 7 6292
    nitrogen compound metabolic process 3.0588E-3 9 1791 7 6292
    posttranscriptional regulation of gene expression 3.186E-3 9 61 2 6292
    regulation of cellular protein metabolic process 3.9454E-3 9 68 2 6292
    regulation of protein metabolic process 4.6571E-3 9 74 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 8.278E-4 9 31 2 6292
    structural constituent of ribosome 2.7255E-3 9 212 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle