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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL16A
  • ribonucleoprotein complex
  • cytoplasm
  • large ribosomal subunit
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL5
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS16B, RPS16A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit biogenesis
  • translation
  • structural constituent of ribosome
  • RPS17B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • intracellular
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • structural constituent of ribosome
  • RPS22A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • intracellular
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • RPS9B
  • small nucleolar ribonucleoprotein complex
  • regulation of translational fidelity
  • translation
  • structural constituent of ribosome
  • SBP1
  • nuclear outer membrane
  • nucleolus
  • negative regulation of translation in response to stress
  • response to stress
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 5.2836E-13 11 101 8 6292
    cytosolic part 2.4947E-12 11 122 8 6292
    ribosomal subunit 6.7404E-11 11 183 8 6292
    cytosol 2.294E-9 11 284 8 6292
    ribosome 2.7101E-9 11 290 8 6292
    cytosolic small ribosomal subunit 2.753E-9 11 38 5 6292
    ribonucleoprotein complex 7.1884E-9 11 514 9 6292
    small ribosomal subunit 8.0106E-8 11 73 5 6292
    non-membrane-bounded organelle 1.7653E-6 11 959 9 6292
    intracellular non-membrane-bounded organelle 1.7653E-6 11 959 9 6292
    90S preribosome 2.668E-6 11 17 3 6292
    preribosome 2.31E-5 11 34 3 6292
    cytosolic large ribosomal subunit 1.2885E-4 11 60 3 6292
    macromolecular complex 1.7215E-4 11 1635 9 6292
    large ribosomal subunit 7.7458E-4 11 110 3 6292
    intracellular organelle part 2.6951E-3 11 2282 9 6292
    organelle part 2.6951E-3 11 2282 9 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 3.0204E-14 11 376 11 6292
    cellular protein metabolic process 3.4344E-9 11 1074 11 6292
    protein metabolic process 6.3855E-9 11 1136 11 6292
    cellular macromolecule biosynthetic process 1.0373E-8 11 1187 11 6292
    macromolecule biosynthetic process 1.0568E-8 11 1189 11 6292
    gene expression 2.4488E-8 11 1283 11 6292
    cellular biosynthetic process 2.2264E-7 11 1567 11 6292
    biosynthetic process 2.841E-7 11 1602 11 6292
    regulation of translation 1.9056E-6 11 57 4 6292
    posttranscriptional regulation of gene expression 2.5085E-6 11 61 4 6292
    regulation of cellular protein metabolic process 3.8902E-6 11 68 4 6292
    regulation of protein metabolic process 5.4669E-6 11 74 4 6292
    cellular macromolecule metabolic process 1.4269E-5 11 2285 11 6292
    macromolecule metabolic process 1.9349E-5 11 2349 11 6292
    ribosomal subunit assembly 9.9258E-5 11 55 3 6292
    ribosome assembly 1.5628E-4 11 64 3 6292
    ribosome biogenesis 1.714E-4 11 346 5 6292
    primary metabolic process 1.9438E-4 11 2896 11 6292
    organelle assembly 1.9559E-4 11 69 3 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.145E-4 11 13 2 6292
    ribonucleoprotein complex biogenesis 2.4767E-4 11 374 5 6292
    cellular metabolic process 3.2347E-4 11 3033 11 6292
    ribonucleoprotein complex assembly 4.5856E-4 11 92 3 6292
    metabolic process 5.03E-4 11 3157 11 6292
    ribosomal small subunit biogenesis 8.8271E-4 11 26 2 6292
    negative regulation of translation in response to stress 1.7483E-3 11 1 1 6292
    regulation of translation in response to stress 1.7483E-3 11 1 1 6292
    ribosomal large subunit assembly 2.1955E-3 11 41 2 6292
    cellular macromolecular complex assembly 3.3093E-3 11 182 3 6292
    cellular component biogenesis 4.2093E-3 11 694 5 6292
    maturation of SSU-rRNA 4.5031E-3 11 59 2 6292
    ribosomal large subunit biogenesis 5.443E-3 11 65 2 6292
    regulation of gene expression 5.4589E-3 11 445 4 6292
    regulation of macromolecule biosynthetic process 5.9597E-3 11 456 4 6292
    regulation of cellular biosynthetic process 6.7432E-3 11 472 4 6292
    regulation of biosynthetic process 6.7944E-3 11 473 4 6292
    regulation of macromolecule metabolic process 7.5943E-3 11 488 4 6292
    cellular macromolecular complex subunit organization 8.8966E-3 11 259 3 6292
    regulation of primary metabolic process 9.1283E-3 11 514 4 6292
    biological regulation 9.6331E-3 11 1213 6 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.6349E-14 11 212 10 6292
    structural molecule activity 1.9021E-12 11 339 10 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle