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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 7 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
HCA4
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • ATP-dependent RNA helicase activity
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL5
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    90S preribosome 5.6973E-7 7 17 3 6292
    cytosolic ribosome 2.1103E-6 7 101 4 6292
    cytosolic part 4.503E-6 7 122 4 6292
    preribosome 4.973E-6 7 34 3 6292
    cytosolic small ribosomal subunit 6.9973E-6 7 38 3 6292
    ribosomal subunit 2.2637E-5 7 183 4 6292
    small ribosomal subunit 5.0731E-5 7 73 3 6292
    ribonucleoprotein complex 6.5267E-5 7 514 5 6292
    non-membrane-bounded organelle 7.5345E-5 7 959 6 6292
    intracellular non-membrane-bounded organelle 7.5345E-5 7 959 6 6292
    cytosol 1.277E-4 7 284 4 6292
    ribosome 1.3857E-4 7 290 4 6292
    nuclear outer membrane 3.7089E-3 7 86 2 6292
    nuclear membrane 4.6971E-3 7 97 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.4008E-7 7 13 3 6292
    ribosome biogenesis 9.3668E-6 7 346 5 6292
    ribonucleoprotein complex biogenesis 1.3745E-5 7 374 5 6292
    translation 1.411E-5 7 376 5 6292
    regulation of translation 2.405E-5 7 57 3 6292
    maturation of SSU-rRNA 2.6695E-5 7 59 3 6292
    posttranscriptional regulation of gene expression 2.9525E-5 7 61 3 6292
    regulation of cellular protein metabolic process 4.0976E-5 7 68 3 6292
    regulation of protein metabolic process 5.2849E-5 7 74 3 6292
    rRNA processing 2.7117E-4 7 128 3 6292
    cellular component biogenesis 2.7953E-4 7 694 5 6292
    rRNA metabolic process 3.3156E-4 7 137 3 6292
    gene expression 4.1171E-4 7 1283 6 6292
    ncRNA processing 1.2438E-3 7 215 3 6292
    ribosomal subunit assembly 1.532E-3 7 55 2 6292
    ribosome assembly 2.0698E-3 7 64 2 6292
    ncRNA metabolic process 2.0862E-3 7 257 3 6292
    cellular protein metabolic process 2.2261E-3 7 1074 5 6292
    organelle assembly 2.4022E-3 7 69 2 6292
    protein metabolic process 2.8929E-3 7 1136 5 6292
    cellular macromolecule biosynthetic process 3.5479E-3 7 1187 5 6292
    macromolecule biosynthetic process 3.5757E-3 7 1189 5 6292
    ribonucleoprotein complex assembly 4.2342E-3 7 92 2 6292
    RNA processing 6.3721E-3 7 380 3 6292
    regulation of gene expression 9.92E-3 7 445 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 8.2387E-7 7 212 5 6292
    structural molecule activity 8.4682E-6 7 339 5 6292
    RNA binding 1.2524E-5 7 367 5 6292
    rRNA binding 1.2639E-4 7 16 2 6292
    nucleic acid binding 2.2923E-4 7 666 5 6292
    binding 5.2851E-3 7 1294 5 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle