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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 12 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

spliceosomal complex 1.7226E-15 12 45 8 6292
ribonucleoprotein complex 6.9243E-10 12 514 10 6292
nuclear part 1.2397E-6 12 1103 10 6292
nucleus 3.4695E-5 12 2041 11 6292
macromolecular complex 5.3141E-5 12 1635 10 6292
organelle part 1.1283E-4 12 2282 11 6292
intracellular organelle part 1.1283E-4 12 2282 11 6292
intracellular organelle 5.3355E-3 12 4070 12 6292
organelle 5.3513E-3 12 4071 12 6292
small nuclear ribonucleoprotein complex 6.105E-3 12 63 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

RNA splicing 2.6849E-18 12 132 11 6292
nuclear mRNA splicing, via spliceosome 3.7654E-17 12 99 10 6292
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 4.1826E-17 12 100 10 6292
RNA splicing, via transesterification reactions 8.4726E-17 12 107 10 6292
mRNA processing 4.1645E-15 12 156 10 6292
mRNA metabolic process 9.9889E-14 12 213 10 6292
RNA processing 3.8587E-13 12 380 11 6292
RNA metabolic process 9.5918E-9 12 954 11 6292
gene expression 2.393E-7 12 1283 11 6292
nucleic acid metabolic process 6.8885E-7 12 1415 11 6292
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.0509E-6 12 1566 11 6292
cellular nitrogen compound metabolic process 7.6146E-6 12 1770 11 6292
nitrogen compound metabolic process 8.6368E-6 12 1791 11 6292
cellular macromolecule metabolic process 1.144E-4 12 2285 11 6292
macromolecule metabolic process 1.5296E-4 12 2349 11 6292
spliceosome assembly 5.0164E-4 12 18 2 6292
ribonucleoprotein complex assembly 6.0496E-4 12 92 3 6292
primary metabolic process 1.3504E-3 12 2896 11 6292
cellular metabolic process 2.1697E-3 12 3033 11 6292
metabolic process 3.2647E-3 12 3157 11 6292
cis assembly of pre-catalytic spliceosome 3.811E-3 12 2 1 6292
cellular macromolecular complex assembly 4.3192E-3 12 182 3 6292
nuclear mRNA cis splicing, via spliceosome 5.7116E-3 12 3 1 6292
generation of catalytic spliceosome for first transesterification step 5.7116E-3 12 3 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

snRNA binding 3.3242E-5 12 5 2 6292
first spliceosomal transesterification activity 4.981E-5 12 6 2 6292
U2 snRNA binding 1.9072E-3 12 1 1 6292
U5 snRNA binding 3.811E-3 12 2 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle