YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Recognition of the intron 5'-splice site by components of the assembling spliceosome. Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript. Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner. Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: nuclear mRNA cis splicing, via spliceosome
Acc: GO:0045292
Aspect: Biological Process
Desc: The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript.
Synonyms:
  • nuclear mRNA cis splicing, via U2-type spliceosome
Proteins in PDR annotated with:
   This term: 3 [Search]
   Term or descendants: 23 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0045292 - nuclear mRNA cis splicing, via spliceosome (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle