YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 13 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
RPA12
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA135
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA14
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
  • regulation of cell size
  • telomere maintenance
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA190
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA34
  • nucleus
  • DNA-directed RNA polymerase I complex
  • nucleolus
    		•
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA43
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA49
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
  • regulation of cell size
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB10
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB5
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB8
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC19
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC40
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPO26
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA-directed RNA polymerase I complex 3.6437E-39 13 14 13 6292
    RNA polymerase complex 5.368E-32 13 31 13 6292
    nuclear DNA-directed RNA polymerase complex 5.368E-32 13 31 13 6292
    DNA-directed RNA polymerase complex 5.368E-32 13 31 13 6292
    nucleolar part 1.9001E-29 13 45 13 6292
    nucleolus 4.7097E-20 13 211 13 6292
    nuclear lumen 1.1883E-15 13 453 13 6292
    organelle lumen 1.6732E-13 13 660 13 6292
    intracellular organelle lumen 1.6732E-13 13 660 13 6292
    DNA-directed RNA polymerase III complex 2.4444E-13 13 17 6 6292
    membrane-enclosed lumen 3.6201E-13 13 700 13 6292
    non-membrane-bounded organelle 2.2351E-11 13 959 13 6292
    intracellular non-membrane-bounded organelle 2.2351E-11 13 959 13 6292
    nuclear part 1.3925E-10 13 1103 13 6292
    protein complex 2.0707E-10 13 1137 13 6292
    DNA-directed RNA polymerase II, core complex 5.3753E-9 13 12 4 6292
    macromolecular complex 2.3774E-8 13 1635 13 6292
    nucleus 4.29E-7 13 2041 13 6292
    organelle part 1.8381E-6 13 2282 13 6292
    intracellular organelle part 1.8381E-6 13 2282 13 6292
    DNA-directed RNA polymerase II, holoenzyme 3.7919E-6 13 56 4 6292
    nucleoplasm part 4.4718E-6 13 245 6 6292
    nucleoplasm 6.9013E-6 13 264 6 6292
    membrane-bounded organelle 1.2767E-3 13 3771 13 6292
    intracellular membrane-bounded organelle 1.2767E-3 13 3771 13 6292
    intracellular organelle 3.4477E-3 13 4070 13 6292
    organelle 3.4587E-3 13 4071 13 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription from RNA polymerase I promoter 3.1169E-32 13 30 13 6292
    transcription, DNA-dependent 4.7164E-15 13 503 13 6292
    RNA biosynthetic process 5.3719E-15 13 508 13 6292
    transcription 1.6014E-14 13 552 13 6292
    RNA metabolic process 2.0874E-11 13 954 13 6292
    transcription from RNA polymerase III promoter 5.3441E-11 13 38 6 6292
    cellular macromolecule biosynthetic process 3.6337E-10 13 1187 13 6292
    macromolecule biosynthetic process 3.7146E-10 13 1189 13 6292
    gene expression 1.0037E-9 13 1283 13 6292
    nucleic acid metabolic process 3.6054E-9 13 1415 13 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.3544E-8 13 1566 13 6292
    cellular biosynthetic process 1.3657E-8 13 1567 13 6292
    biosynthetic process 1.822E-8 13 1602 13 6292
    cellular nitrogen compound metabolic process 6.6927E-8 13 1770 13 6292
    nitrogen compound metabolic process 7.8058E-8 13 1791 13 6292
    ribosome biogenesis 1.8437E-6 13 346 7 6292
    cellular macromolecule metabolic process 1.8698E-6 13 2285 13 6292
    macromolecule metabolic process 2.6802E-6 13 2349 13 6292
    ribonucleoprotein complex biogenesis 3.1161E-6 13 374 7 6292
    primary metabolic process 4.1002E-5 13 2896 13 6292
    cellular metabolic process 7.4867E-5 13 3033 13 6292
    metabolic process 1.2617E-4 13 3157 13 6292
    cellular component biogenesis 1.8193E-4 13 694 7 6292
    transcription from RNA polymerase II promoter 3.8457E-3 13 335 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    RNA polymerase activity 2.4152E-31 13 34 13 6292
    DNA-directed RNA polymerase activity 2.4152E-31 13 34 13 6292
    nucleotidyltransferase activity 2.2046E-21 13 168 13 6292
    transferase activity, transferring phosphorus-containing groups 4.3844E-16 13 420 13 6292
    transferase activity 1.9832E-12 13 797 13 6292
    catalytic activity 8.4537E-7 13 2150 13 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle