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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.540962115882]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
CDC24
  • nucleus
  • incipient cellular bud site
  • cellular bud neck
  • mating projection tip
    		•
  • budding cell isotropic bud growth
  • small GTPase mediated signal transduction
  • regulation of exit from mitosis
  • pseudohyphal growth
  • chitin localization
  • invasive growth in response to glucose limitation
  • cell morphogenesis involved in conjugation with cellular fusion
  • budding cell apical bud growth
  • pheromone-dependent signal transduction involved in conjugation with cellular fusion
    		•
  • Rho guanyl-nucleotide exchange factor activity
  • signal transducer activity
    		•
    CDC42
  • cellular bud tip
  • soluble fraction
  • cellular bud neck
  • mating projection tip
  • plasma membrane
    		•
  • budding cell isotropic bud growth
  • regulation of initiation of mating projection growth
  • regulation of exit from mitosis
  • pseudohyphal growth
  • invasive growth in response to glucose limitation
  • Rho protein signal transduction
  • exocytosis
  • budding cell apical bud growth
  • pheromone-dependent signal transduction involved in conjugation with cellular fusion
    		•
  • GTPase activity
  • signal transducer activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    mating projection tip 3.0063E-5 2 35 2 6292
    cell projection part 4.3504E-5 2 42 2 6292
    cell projection 5.9419E-5 2 49 2 6292
    mating projection 5.9419E-5 2 49 2 6292
    cellular bud neck 4.1715E-4 2 129 2 6292
    cellular bud 6.9196E-4 2 166 2 6292
    site of polarized growth 7.0879E-4 2 168 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    budding cell isotropic bud growth 1.4147E-6 2 8 2 6292
    budding cell apical bud growth 2.2737E-6 2 10 2 6292
    cell morphogenesis involved in conjugation with cellular fusion 1.1672E-5 2 22 2 6292
    cell morphogenesis involved in conjugation 1.3945E-5 2 24 2 6292
    regulation of exit from mitosis 1.5158E-5 2 25 2 6292
    exit from mitosis 1.5158E-5 2 25 2 6292
    regulation of conjugation with cellular fusion by signal transduction 1.7735E-5 2 27 2 6292
    pheromone-dependent signal transduction involved in conjugation with cellular fusion 1.7735E-5 2 27 2 6292
    G-protein coupled receptor protein signaling pathway 2.3495E-5 2 31 2 6292
    regulation of multi-organism process 2.5061E-5 2 32 2 6292
    regulation of conjugation 2.5061E-5 2 32 2 6292
    regulation of conjugation with cellular fusion 2.5061E-5 2 32 2 6292
    cell surface receptor linked signaling pathway 2.5061E-5 2 32 2 6292
    budding cell bud growth 2.8346E-5 2 34 2 6292
    invasive growth in response to glucose limitation 5.4619E-5 2 47 2 6292
    small GTPase mediated signal transduction 1.0186E-4 2 64 2 6292
    pseudohyphal growth 1.151E-4 2 68 2 6292
    regulation of mitotic cell cycle 1.2556E-4 2 71 2 6292
    response to pheromone involved in conjugation with cellular fusion 1.44E-4 2 76 2 6292
    regulation of cell cycle process 1.6371E-4 2 81 2 6292
    cell growth 1.7194E-4 2 83 2 6292
    cell budding 2.0236E-4 2 90 2 6292
    filamentous growth of a population of unicellular organisms 2.0236E-4 2 90 2 6292
    asexual reproduction 2.0236E-4 2 90 2 6292
    growth of unicellular organism as a thread of attached cells 2.0236E-4 2 90 2 6292
    response to pheromone 2.3525E-4 2 97 2 6292
    filamentous growth 2.8118E-4 2 106 2 6292
    cellular response to chemical stimulus 2.8654E-4 2 107 2 6292
    regulation of cell size 3.0847E-4 2 111 2 6292
    chitin localization 3.1786E-4 2 1 1 6292
    polysaccharide localization 3.1786E-4 2 1 1 6292
    regulation of anatomical structure size 3.2544E-4 2 114 2 6292
    regulation of cellular component size 3.2544E-4 2 114 2 6292
    intracellular signal transduction 3.312E-4 2 115 2 6292
    cell morphogenesis 3.9158E-4 2 125 2 6292
    conjugation with cellular fusion 3.9158E-4 2 125 2 6292
    conjugation 3.979E-4 2 126 2 6292
    M phase of mitotic cell cycle 4.1068E-4 2 128 2 6292
    regulation of cell cycle 4.3024E-4 2 131 2 6292
    response to organic substance 4.7071E-4 2 137 2 6292
    cellular component morphogenesis 4.7763E-4 2 138 2 6292
    multi-organism process 5.13E-4 2 143 2 6292
    intracellular signaling pathway 5.2022E-4 2 144 2 6292
    growth 5.275E-4 2 145 2 6292
    cell division 5.275E-4 2 145 2 6292
    reproductive developmental process 5.7222E-4 2 151 2 6292
    signaling pathway 8.5067E-4 2 184 2 6292
    reproductive cellular process 1.1194E-3 2 211 2 6292
    reproductive process 1.1301E-3 2 212 2 6292
    signal transduction 1.1516E-3 2 214 2 6292
    signal transmission 1.1841E-3 2 217 2 6292
    signaling process 1.1841E-3 2 217 2 6292
    reproduction of a single-celled organism 1.1841E-3 2 217 2 6292
    regulation of initiation of mating projection growth 1.2712E-3 2 4 1 6292
    sexual reproduction 1.3656E-3 2 233 2 6292
    signaling 1.598E-3 2 252 2 6292
    mitotic cell cycle 1.6363E-3 2 255 2 6292
    anatomical structure morphogenesis 1.6621E-3 2 257 2 6292
    anatomical structure development 1.7012E-3 2 260 2 6292
    cellular developmental process 1.9175E-3 2 276 2 6292
    M phase 2.1762E-3 2 294 2 6292
    regulation of cell projection organization 2.224E-3 2 7 1 6292
    regulation of cell projection assembly 2.224E-3 2 7 1 6292
    regulation of mating projection assembly 2.224E-3 2 7 1 6292
    reproduction 2.7096E-3 2 328 2 6292
    developmental process 2.7595E-3 2 331 2 6292
    regulation of cell morphogenesis 2.859E-3 2 9 1 6292
    mating projection assembly 3.1764E-3 2 10 1 6292
    regulation of response to stimulus 3.1764E-3 2 10 1 6292
    cell projection assembly 3.4937E-3 2 11 1 6292
    cell projection organization 3.4937E-3 2 11 1 6292
    regulation of developmental process 3.4937E-3 2 11 1 6292
    regulation of anatomical structure morphogenesis 3.4937E-3 2 11 1 6292
    cell cycle phase 3.5621E-3 2 376 2 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    response to chemical stimulus 3.6769E-3 2 382 2 6292
    regulation of cellular component biogenesis 5.7138E-3 2 18 1 6292
    cell cycle process 6.0534E-3 2 490 2 6292
    Rho protein signal transduction 6.3477E-3 2 20 1 6292
    cell cycle 6.95E-3 2 525 2 6292
    regulation of biological quality 7.6561E-3 2 551 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    molecular transducer activity 1.5966E-4 2 80 2 6292
    signal transducer activity 1.5966E-4 2 80 2 6292
    Rho guanyl-nucleotide exchange factor activity 1.2712E-3 2 4 1 6292
    Ras guanyl-nucleotide exchange factor activity 5.7138E-3 2 18 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle