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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.037] [SVM Score: 0.658108462294]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

mRNA cap binding complex 1.5158E-7 2 3 2 6292
RNA cap binding complex 7.579E-7 2 6 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

negative regulation of translation 1.0611E-6 2 7 2 6292
negative regulation of cellular protein metabolic process 5.3053E-6 2 15 2 6292
negative regulation of protein metabolic process 6.0632E-6 2 16 2 6292
regulation of translation 8.0641E-5 2 57 2 6292
posttranscriptional regulation of gene expression 9.2464E-5 2 61 2 6292
regulation of cellular protein metabolic process 1.151E-4 2 68 2 6292
regulation of protein metabolic process 1.3647E-4 2 74 2 6292
negative regulation of macromolecule biosynthetic process 7.6927E-4 2 175 2 6292
negative regulation of biosynthetic process 8.9766E-4 2 189 2 6292
negative regulation of cellular biosynthetic process 8.9766E-4 2 189 2 6292
negative regulation of macromolecule metabolic process 9.2646E-4 2 192 2 6292
negative regulation of cellular metabolic process 1.0983E-3 2 209 2 6292
negative regulation of metabolic process 1.1088E-3 2 210 2 6292
negative regulation of cellular process 1.5726E-3 2 250 2 6292
negative regulation of biological process 1.6107E-3 2 253 2 6292
translation 3.5621E-3 2 376 2 6292
regulation of gene expression 4.9915E-3 2 445 2 6292
regulation of macromolecule biosynthetic process 5.2416E-3 2 456 2 6292
regulation of cellular biosynthetic process 5.6164E-3 2 472 2 6292
regulation of biosynthetic process 5.6402E-3 2 473 2 6292
regulation of macromolecule metabolic process 6.004E-3 2 488 2 6292
regulation of primary metabolic process 6.6615E-3 2 514 2 6292
regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
regulation of metabolic process 7.5452E-3 2 547 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

translation initiation factor binding 3.1786E-4 2 1 1 6292
eukaryotic initiation factor 4E binding 3.1786E-4 2 1 1 6292
translation regulator activity 3.4937E-3 2 11 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle