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Protein Overview: AFI1

General Information:
Name(s) found: AFI1 / YOR129C [SGD]
Description(s) found:
Found 31 descriptions.
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  • Arf3p polarization-specific docking factor, required for the polarized distribution of the ADP-ribosylation factor, Arf3p; participates in polarity development and maintenance of a normal haploid budding pattern; interacts with Cnm7p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 893 amino acids

    Gene Ontology:
    Cellular Component: outer plaque of spindle pole body [IPILink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: response to drug [IGILink to PubMed article][IMPLink to PubMed article]
    cellular cation homeostasis [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: structural constituent of cytoskeleton [IGILink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRRELNNSI SNRSIENESF PFERPNVSYI ISAEFDNKLG PILKHQYPKD IPGFNQFSHE  60
   61 QRNGNTSVSM NLASLMIPSS IERNPGKQDI TVFTLYYNKF TQNYQLFPVP KDPRFSFNLH 120
  121 HREQSDGSVT NSIYYDAENH QDAKNNRYTI VLEDDELECQ EVQNNQKAID NEPLFFINVA 180
  181 NTVLDTTNDR GAVIKSIAIG TPLKTFFAFK NIIVLVLDLY MKAPTQAAAT DILLDCFNML 240
  241 NSIDLTLIND IHSKSSIQEV LHSIHDESII TKVFLDPDST LKKLFCINGF DTKDKYGNIV 300
  301 TFHDQLIQYH FTRFQPKTLP PFLLKIPLQF NMIRREPIYI ENDYNELVLK FLDKFVPYLL 360
  361 KAGQKVNAWK LVINSTKLSK EDLCAFILSL ANITATYASD PQSYFKGNAA LIFPYMDISL 420
  421 VDGLRAYVAS NSDFVGCFAI IGTANPIFRY QLDIWDYYYD VDEGVFYENN SPEKEKPDTV 480
  481 AEVKIGPNPL RKIFNRPHFS TNAVNESQVN LGQKLFSLLI DEYHDSDTIM SVLRRLNVLQ 540
  541 LENLLDALKR REIPPNIALK DEYIMFYKDF FIFPEFFDYF TLHSIELLSN LDNCLFSLGN 600
  601 TCQLFSTEQI YSQLSQILDI VKELFRMVSV SRTNIEKFLN ACLNYSPFKI LPTAQLHGDN 660
  661 ISRWSFESEV RQGFDNFNSY MGIEKDPHGV IVSAIDLFTQ IYSFDILAFF LTFITKESGQ 720
  721 DLPFTKSLSR RRTYLTRIAQ SSSLRQFLQL STRPNIRILG GNGQGTGNSN YPEFTNASSV 780
  781 ISPKLRASPL LERRASKICY AITKLLYRLE CHPIGMALLK KYLHNQLREA YLESKRHFIS 840
  841 KKGDSTNTSS TIASSSFAGA SVPLSSNESG MLNGLKQINE QQESTLETTQ KED

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) AFI1 SPC42 SPC97

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run BOI1 Sample bob1 (2nd set) from october 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen ARF3 AFI1 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data AFI1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..105] MSA 1.002946 View MSA. No confident structure predictions are available.
    2 View Details [106..655] deduced N/A No confident structure predictions are available.
    3 View Details [656..893] ab initio 7.1 No description for 1l9uD was found.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle