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Protein Overview: YGR287C

General Information:
Name(s) found: YGR287C [SGD]
Description(s) found:
Found 30 descriptions.
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  • Isomaltase (alpha-D-glucosidase); may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein detected in purified mitochondria in high-throughput studies [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 589 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    ribosome [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTISSAHPET EPKWWKEATF YQIYPASFKD SNDDGWGDMK GIASKLEYIK ELGADAIWIS  60
   61 PFYDSPQDDM GYDIANYEKV WPTYGTNEDC FALIEKTHKL GMKFITDLVI NHCSSEHEWF 120
  121 KESRSSKTNP KRDWFFWRPP KGYDAEGKPI PPNNWKSYFG GSAWTFDEKT QEFYLRLFCS 180
  181 TQPDLNWENE DCRKAIYESA VGYWLDHGVD GFRIDVGSLY SKVVGLPDAP VVDKNSTWQS 240
  241 SDPYTLNGPR IHEFHQEMNQ FIRNRVKDGR EIMTVGEMQH ASDETKRLYT SASRHELSEL 300
  301 FNFSHTDVGT SPLFRYNLVP FELKDWKIAL AELFRYINGT DCWSTIYLEN HDQPRSITRF 360
  361 GDDSPKNRVI SGKLLSVLLS ALTGTLYVYQ GQELGQINFK NWPVEKYEDV EIRNNYNAIK 420
  421 EEHGENSEEM KKFLEAIALI SRDHARTPMQ WSREEPNAGF SGPSAKPWFY LNDSFREGIN 480
  481 VEDEIKDPNS VLNFWKEALK FRKAHKDITV YGYDFEFIDL DNKKLFSFTK KYNNKTLFAA 540
  541 LNFSSDATDF KIPNDDSSFK LEFGNYPKKE VDASSRTLKP WEGRIYISE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..302] PSI-BLAST 2190.0 Oligo-1,6-glucosidase; Oligo-1,6, glucosidase
    2 View Details [303..589] PSI-BLAST 2190.0 Oligo-1,6-glucosidase; Oligo-1,6, glucosidase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  5.72449317118946 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  5.38610972475995 bayes_pls_golite062009
  • hydrolase activity
    		•  4.42755848458375 bayes_pls_golite062009
  • hexosaminidase activity
    		•  2.6383220379017 bayes_pls_golite062009
  • chitinase activity
    		•  2.45357334610104 bayes_pls_golite062009
  • structural molecule activity
    		•  2.28030619331997 bayes_pls_golite062009
  • beta-N-acetylhexosaminidase activity
    		•  2.12259271877403 bayes_pls_golite062009
  • trehalase activity
    		•  2.11042620996316 bayes_pls_golite062009
  • alpha-amylase activity
    		•  2.09193270404736 bayes_pls_golite062009
  • amylase activity
    		•  2.03484942782894 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • glucosidase activity
    		•  1.63850753281742 bayes_pls_golite062009
  • transporter activity
    		•  1.28975867300692 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  1.09355005521552 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  1.08320932161637 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.06875155491269 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.798668027833638 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  0.726290283967376 bayes_pls_golite062009
  • galactosidase activity
    		•  0.67508380605029 bayes_pls_golite062009
  • binding
    		•  0.63693798355947 bayes_pls_golite062009
  • alpha-glucosidase activity
    		•  0.54694531123812 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.543615761700598 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.4998423581103 bayes_pls_golite062009
  • maltase activity
    		•  0.442635030512661 bayes_pls_golite062009
  • sugar binding
    		•  0.36459095255871 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.266938437560648 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.247544462005515 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle