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Protein Overview: NCOA2_DANRE

General Information:
Name(s) found: NCOA2_DANRE [Swiss-Prot]
Description(s) found:
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  • gi|82112094|sp|Q98TW1.1|NCOA2_DANRE RecName: Full=Nuclear receptor coactivator 2; Short=NCoA-2; Short=NCoA2; AltName: Full=Transcriptional intermediary factor 2; AltName: Full=Glucocorticoid receptor-interacting protein 1; AltName: Full=Steroid receptor c [NCBI NR]
  • gi|37785625|gb|AAP69780.1| nuclear receptor coactivator [Danio rerio] [NCBI NR]
  • gi|18859481|ref|NP_571852.1| nuclear receptor coactivator 2 [Danio rerio] [NCBI NR]
  • gi|13022010|gb|AAK11608.1|AF323989_1 transcriptional intermediary factor 2 [Danio rerio] [NCBI NR]
  • Nuclear receptor coactivator 2 OS=Danio rerio GN=ncoa2 PE=1 SV=1 [Swiss-Prot]
  • transcriptional intermediary factor 2 [071204_hmrz_cont.fasta]
  • transcriptional intermediary factor 2 [Danio rerio]gi|13022010|gb|AAK11608.1| transcriptional intermediary factor 2 [Danio rerio]gi|37785625|gb|AAP69780.1| nuclear receptor coactivator [Danio rerio] [nrdb_11152004_Chlamydomonas]
  • transcriptional intermediary factor 2 [Danio rerio] [nr-271106-contam.fasta]
  • nuclear receptor coactivator [Danio rerio] [nr-271106-contam.fasta]
  • nuclear receptor coactivator 2 [Danio rerio] [NCBI-RefSeq_D_rerio_na_08-30-2010_reversed.fasta]
  • RecName: Full=Nuclear receptor coactivator 2; Short=NCoA-2; Short=NCoA2; AltName: Full=Glucocorticoid receptor-interacting protein 1; AltName: Full=Steroid receptor coactivator 2; AltName: Full=Transcriptional intermediary factor 2 [NCBI_RefSeq_D_rerio_20120531_05-31-2012_reversed.fasta]
    • Organism: Danio rerio
    Length: 1505 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    Biological Process: embryonic development [IMP]
    transcription [IEA]
    signal transduction [IEA]
    multicellular organismal development [IEA]
    myeloid cell differentiation [IMP]
    regulation of transcription, DNA-dependent [IEA]
    regulation of transcription [IEA]
    granulocyte differentiation [IMP]
    primitive hemopoiesis [IMP]
    Molecular Function: transcription coactivator activity [IEA]
    transcription regulator activity [IEA]
    nuclear hormone receptor binding [IEA]
    receptor activity [IEA]
    signal transducer activity [IEA]
    thyroid hormone receptor binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAVGENSSD PARSEAQKRK EGPSDLLGPS PKRSTEKRNR EHESKYIEEL AELIFANFND  60
   61 IDNFNVKPDK CAILKETVKQ IRQIKEQEKA AAANEDEVQK ADVSSTGQSV IDKDALGPMM 120
  121 LEALDGFFFV VNMEGNIVFV SENVTQYLRY NQEELMNTSV YSILHVGDHA EFIKNLLPKS 180
  181 HVNGVPWSSE NPRRNSHTFN CRMLVNPHSE AEETQDHEAQ QKYETMQCFA VSEPKSIKEE 240
  241 GEDFQSCLIC VARRVPMKER PMLPTQESFT TRQDLQGKIT SLDTSLLRAS MKPGWEDLVR 300
  301 RCIQRFHLQN DGDISFAKRH QQEVIRHGQA FSPIYRFSLS DGTIVSAHTK SKLVRSSSTN 360
  361 EPQLYMSLHI LQREQPVCGM ASDLGNAQTM GKPMNPMSSP NTAGSSCTPQ GQDATISSNT 420
  421 STFPSPGAQK EPGAMHRFGC PGTMSHSATM QAATPQGSGY PLKLSSPSQG SPGMLSPRHR 480
  481 ASPGVAGSPR LPPPQFSPAG SLHSPASMCT SSTGGNGGAG ANHGYTSSSL NALQALSECH 540
  541 GVSHGQSLGS PDRKLGSPAA HSVAVSHHLI NKMSVPESFG EQNQSEQGTP GQDEGIDLPR 600
  601 DEKGNLGQFG NLDGSDPQSR LRDNKSHTKL LQLLTTKTEP IESTSPPPMA GGEPGCKDGG 660
  661 AGNGGMGSQG GNGSHATSLK EKHKILHRLL QNSSSPVDLA KLTAEATGKE LCQDSAGGTA 720
  721 GVPELAIKQE PVSPKKKDNA LLRYLLDKDD NVLKGKGIKM EPGEIKEEGG KMTGIKTEKT 780
  781 DGGYDRVEPS SELDDILDDL QNSQPGLFTD SRPVSLPSAV DKQSIINDIL QMTGESGANM 840
  841 SPQQQRALQT AVSQQNFPAP RPGQPGRAPP VRSVSLDMNM PPKGAQGQYP MMRNNNPYSI 900
  901 MQQQGMMGNH AVMPNQPNMV NAGVMGNNGP RVGMQQDGWG AQGTVGSAAS PATAAPAGQH 960
  961 SLPQGALHSR MVPNPATGMP MRPNSQPGPR PMLQPQMMAN AQSNMDMGMA GHQFPQQQAP1020
 1021 PNQTAPWPDS VMPIEPVPFG NQSSSMYGGS QEDVLCPPAS EGPADEGALL SQLYSALKDF1080
 1081 DGLEEIDRAL GIPALVGQAQ PVEQDQFPGQ DPSMMMDQKP PMYGQQQYAS SPANMQQAGY1140
 1141 TPMQDATFHG LQGQMGQRPG YPMLRMQARP GLRPGGVVPN QPNTLRLQLQ HRLQAQQNRQ1200
 1201 PMMNQMGGVS NMNLPLRPNV PNQGTINAQM LAQRQRELLS NHLRQRQLDQ QRQQQQQQQQ1260
 1261 QRSLAMRAQG LTMPPNMAAA AAGMPGAMSN PRIPQANLQQ FPYPPNYGTG LASPPPSTSP1320
 1321 FSPGSPNLPA PQLLSHSAMH GSQMSLANQG MLGSLSGQFG AVMSPQMQHS AFQFPSSGMS1380
 1381 QQSDGGFGGA ATPQSPLMSP RMGHAQSPMM QQAQGNSSFQ SSPDMNGWPQ GNINTNSMFT1440
 1441 QQSPPQFSQQ ANNNMYNGNG MNLNVSMAAN SSNMGQMGNQ MSMSSMNSGP GSGMANMGPE1500
 1501 QQKYC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

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    Created and Maintained by: Michael Riffle