Protein Overview: NPCL1_RAT

General Information:
Name(s) found:	NPCL1_RAT [Swiss-Prot]
Description(s) found: Found 17 descriptions. SHOW ALL	Niemann-Pick C1-like protein 1 OS=Rattus norvegicus GN=Npc1l1 PE=1 SV=1 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	1331 amino acids
Gene Ontology:
Cellular Component:	brush border membrane [IDA] integral to membrane [UNKNOWN][IEA] plasma membrane [IEA] apical plasma membrane [IEA]
Biological Process:	response to drug [IEP] cholesterol biosynthetic process [UNKNOWN] cholesterol metabolic process [IEA] steroid metabolic process [IEA] intestinal cholesterol absorption [UNKNOWN] lipoprotein metabolic process [UNKNOWN] cholesterol transport [UNKNOWN][IEA] cholesterol homeostasis [UNKNOWN]
Molecular Function:	drug binding [IDA] hedgehog receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAAWLGWLL WALLLSAAQG ELYTPKHEAG VCTFYEECGK NPELSGGLTS LSNVSCLSNT  60
   61 PARHVTGEHL ALLQRICPRL YNGPNTTFAC CSTKQLLSLE SSMSITKALL TRCPACSDNF 120
  121 VSLHCHNTCS PDQSLFINVT RVVERGAGEP PAVVAYEAFY QRSFAEKAYE SCSQVRIPAA 180
  181 ASLAVGSMCG VYGSALCNAQ RWLNFQGDTG NGLAPLDITF HLLEPGQALP DGIQPLNGKI 240
  241 APCNESQGDD SAVCSCQDCA ASCPVIPPPE ALRPSFYMGR MPGWLALIII FTAVFVLLSA 300
  301 VLVRLRVVSN RNKNKAEGPQ EAPKLPHKHK LSPHTILGRF FQNWGTRVAS WPLTVLALSF 360
  361 IVVIALAAGL TFIELTTDPV ELWSAPKSQA RKEKSFHDEH FGPFFRTNQI FVTARNRSSY 420
  421 KYDSLLLGSK NFSGILSLDF LLELLELQER LRHLQVWSPE AERNISLQDI CYAPLNPYNT 480
  481 SLSDCCVNSL LQYFQNNRTL LMLTANQTLN GQTSLVDWKD HFLYCANAPL TFKDGTSLAL 540
  541 SCMADYGAPV FPFLAVGGYQ GTDYSEAEAL IITFSLNNYP ADDPRMAQAK LWEEAFLKEM 600
  601 ESFQRNTSDK FQVAFSAERS LEDEINRTTI QDLPVFAVSY IIVFLYISLA LGSYSRCSRV 660
  661 AVESKATLGL GGVIVVLGAV LAAMGFYSYL GVPSSLVIIQ VVPFLVLAVG ADNIFIFVLE 720
  721 YQRLPRMPGE QREAHIGRTL GSVAPSMLLC SLSEAICFFL GALTPMPAVR TFALTSGLAI 780
  781 ILDFLLQMTA FVALLSLDSK RQEASRPDVL CCFSTRKLPP PKEKEGLLLR FFRKIYAPFL 840
  841 LHRFIRPVVM LLFLTLFGAN LYLMCNINVG LDQELALPKD SYLIDYFLFL NRYLEVGPPV 900
  901 YFVTTSGFNF SSEAGMNATC SSAGCKSFSL TQKIQYASEF PDQSYVAIAA SSWVDDFIDW 960
  961 LTPSSSCCRL YIRGPHKDEF CPSTDTSFNC LKNCMNRTLG PVRPTAEQFH KYLPWFLNDP1020
 1021 PNIRCPKGGL AAYRTSVNLS SDGQVIASQF MAYHKPLRNS QDFTEALRAS RLLAANITAD1080
 1081 LRKVPGTDPN FEVFPYTISN VFYQQYLTVL PEGIFTLALC FVPTFVVCYL LLGLDMCSGI1140
 1141 LNLLSIIMIL VDTIGLMAVW GISYNAVSLI NLVTAVGMSV EFVSHITRSF AVSTKPTRLE1200
 1201 RAKDATVFMG SAVFAGVAMT NFPGILILGF AQAQLIQIFF FRLNLLITLL GLLHGLVFLP1260
 1261 VVLSYLGPDV NQALVQEEKL ASEAAVAPEP SCPQYPSPAD ADANVNYGFA PELAHGANAA1320
 1321 RSSLPKSDQK F

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: NPCL1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: