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Protein Overview: PGDH_RAT

General Information:
Name(s) found: PGDH_RAT [Swiss-Prot]
Description(s) found:
Found 15 descriptions.
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  • 15-hydroxyprostaglandin dehydrogenase [NAD(+)] OS=Rattus norvegicus GN=Hpgd PE=2 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 266 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IEA]
    cytoplasm [UNKNOWN][IEA]
    [NOT]nucleolus [UNKNOWN]
    Biological Process: lipid metabolic process [IEA]
    transforming growth factor beta receptor signaling pathway [UNKNOWN][ISS]
    negative regulation of cell cycle [UNKNOWN][ISS]
    female pregnancy [UNKNOWN][ISS]
    prostaglandin metabolic process [UNKNOWN][ISS]
    oxidation reduction [IEA]
    fatty acid metabolic process [IEA]
    parturition [UNKNOWN][ISS]
    Molecular Function: 15-hydroxyprostaglandin dehydrogenase (NAD+) activity [UNKNOWN][IDA][ISS]
    prostaglandin E receptor activity [UNKNOWN][ISS]
    catalytic activity [UNKNOWN][ISS]
    oxidoreductase activity [IEA]
    NAD or NADH binding [UNKNOWN][ISS]
    binding [IEA]
    NAD binding [UNKNOWN][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHVNGKVALV TGAAQGIGKA FTEALLLHGA KVALVDWNLE TGVKCKAALD EQFEPQKTLF  60
   61 IQCDVADQKQ LRDTFRKVVD HFGRLDILVN NAGVNNEKNW EQTLQINLVS VISGTYLGLD 120
  121 YMSKQNGGEG GIIINISSIA GLMPVAQQPV YCASKHGIIG FTRSAAMAAN LMKSGVRLNV 180
  181 ICPGFVKTPI LESIEKEENM GQYIEYTDQI KAMMKFYGIL DPSAIANGLI NLIEDDALNG 240
  241 AIMKITASKG IHFQDYDLFP SFSKAP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.56

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle