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Protein Overview: ADCYA_RAT

General Information:
Name(s) found: ADCYA_RAT [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Adenylate cyclase type 10 OS=Rattus norvegicus GN=Adcy10 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 1608 amino acids

    Gene Ontology:
    Cellular Component: neuronal cell body [IDA]
    plasma membrane [UNKNOWN][IEA]
    growth cone [IDA]
    dendrite [IDA]
    soluble fraction [IDA]
    cytoskeleton [IEA]
    perinuclear region of cytoplasm [IEA]
    apical part of cell [IDA]
    cytoplasm [IDA]
    centriole [IEA]
    basal part of cell [IDA]
    mitochondrion [IEA]
    cytosol [IDA]
    axon [IDA]
    Biological Process: inhibition of adenylate cyclase activity by G-protein signaling pathway [UNKNOWN]
    cAMP biosynthetic process [IDA][IEA][IMP]
    activation of protein kinase A activity [UNKNOWN]
    spermatogenesis [IEA]
    positive regulation of apoptosis [IMP]
    activation of adenylate cyclase activity by G-protein signaling pathway [UNKNOWN]
    cyclic nucleotide biosynthetic process [IEA]
    hormone-mediated signaling pathway [UNKNOWN]
    Molecular Function: nucleotide binding [IEA]
    magnesium ion binding [IEA]
    ATP binding [IEA]
    phosphorus-oxygen lyase activity [IEA]
    manganese ion binding [IDA]
    adenylate cyclase activity [IDA][IEA][IMP]
    ATPase binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSARRQELQD RAIVKIAAHL PDLIVYGDFS PERPSVKCFD GVLMFVDISG FTAMTEKFST  60
   61 AMYMDRGAEQ LVEILNYYIS AIVEKVLIFG GDILKFAGDA LLALWKVERK QLKNIITVVI 120
  121 KCSLEIHGLF EAKEVEEGLD IRVKIGLAAG HITMLVFGDE TRNYFLVIGQ AVDDVRLAQN 180
  181 MAQMNDVILS PNCWQLCDRS MIEIERIPDQ RAVKVSFLKP PPTFNFDEFF AKCMAFMDYY 240
  241 PSGDHKNFLR LACMLESDPE LELSLQKYVM EIILKQIDDK QLRGYLSELR PVTIVFVNLM 300
  301 FKEQDKAEVI GSAIQAACVH ITSVLKVFRG QINKVFMFDK GCSFLCVFGF PGEKAPDEIT 360
  361 HALESAVDIF DFCSQVHKIR TVSIGVASGI VFCGIVGHTV RHEYTVIGQK VNIAARMMMY 420
  421 YPGIVTCDSV TYDGSNLPAY FFKELPKKVM KGVADPGPVY QCLGLNEKVM FGMAYLICNR 480
  481 YEGYPLLGRV REIDYFMSTM KDFLMTNCSR VLMYEGLPGY GKSQVLMEIE YLASQHENHR 540
  541 AVAIALTKIS FHQNFYTIQI LMANVLGLDT CKHYKERQTN LQNRVKTLLD DKYHCLLNDI 600
  601 FHVQFPVSRE MSRMSKIRKQ KQLEALFMKI LEQTVREERI IFIIDEAQFV DVASWAFIEK 660
  661 LIRSMPIFIV MSLCPFPETP CAAANAIMKN RNTTYITLGT MQPQEIRDKV CVDLSVSSIP 720
  721 RELDSYLVEG SCGIPYYCEE LLKNLDHHRI LIFQQAEAEE KTNVTWNNLF KYSVKPTEDM 780
  781 YLYTSIAAGQ KEACYLTSGV RLKNLSPPAS LKEISLVQLD SMSLSHQMLV RCAAIIGLTF 840
  841 TTELLFEILP CWNMKMMIKA LATLVESNVF DCFRSSKDLQ LALKQNVTTF EVHYRSLSLK 900
  901 SKEGLAYSEE EQLREMEGEV IECRILRFCR PIMQKTAYEL WLKDQKKVLH LKCARFLEES 960
  961 AHRCNHCRNR DFIPYHHFIA DIRLNTLDMD TVKKMVKSHG FKTEDEVIFS KSEIPRKFKF1020
 1021 PENISITETR EKILHFFDNV IIKMRTSQDD VIPLESCHCE ELLQIVILPL AQHFVALEEN1080
 1081 NKALYYFLEL ASAYLILGDN YNAYMYLGEG ERLLKSLTNE DSWSQTFEYA TFYSLKGEIC1140
 1141 FNMGQMVLAK KMLRKALKLL NRMFPCNLLS LTFQMHIEKN RLSHFMNQHT QEGSLPGKKL1200
 1201 AQLFLQSSCF SLLWKIYSLN FFFHYKYYGR LAAIMQMNTS LETQNNFQII KAFLDFSLYR1260
 1261 HLAGYEGVWF KYEILVMEQL LNLPLKGEAF EIMAYAADAL GHIKFLTGHL DLAIELGSRA1320
 1321 HKMWSLLRNP NKYHMVLCRL SKPLFLKSRY KHLVQVLGWL WDLSVTEEHI FSKAFFYFVC1380
 1381 LDIMLYSGFI YRTFEECLEF IHHNEDNRIL KFQSGLLLGL YSCIAVWYAR LQEWDNFYKF1440
 1441 SNRAKTLVTR RTPTVLYYEG ISRYMEGQVL HLQKQIEEQA ENAQDSGVEL LKALETLVAQ1500
 1501 NTTGPVFYPR LYHLMAYVCI LMGDGHSCDF FLNTALELSE TQGNLLEKCW LSMSKEWWYS1560
 1561 APELTGDQWL QTVLSLPSWD KIVSGNVTLQ DVQKNKFLMR VNILDNPF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.42

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle