Protein Overview: IOD3_RAT

General Information:
Name(s) found:	IOD3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|182702119\|sp\|P49897.2\|IOD3_RAT RecName: Full=Type III iodothyronine deiodinase; AltName: Full=Type-III 5'-deiodinase; AltName: Full=Type 3 DI; AltName: Full=DIOIII; AltName: Full=5DIII [NCBI NR] gi\|15011855\|ref\|NP_058906.2\| deiodinase, iodothyronine, type III [Rattus norvegicus] [NCBI NR] gi\|14717789\|gb\|AAC52241.2\| type III iodiothyronine deiodinase [Rattus norvegicus] [NCBI NR] Type III iodothyronine deiodinase OS=Rattus norvegicus GN=Dio3 PE=1 SV=2 [Swiss-Prot] deiodinase, iodothyronine, type III; deiodinase, iodothyronine type III; deiodinase, iodothyronine, type 3; deiodinase iodothyronine type III; deiodinase iodothyronine type 3 [HMR_022704-rand.fasta] deiodinase, iodothyronine, type III; deiodinase, iodothyronine, type 3; deiodinase iodothyronine type III; deiodinase iodothyronine type 3; deiodinase, iodothyronine type III [071204_hmrz_cont.fasta] deiodinase, iodothyronine, type III [Rattus norvegicus]gi\|14717789\|gb\|AAC52241.2\| type III iodiothyronine deiodinase [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] (NM_017210) deiodinase, iodothyronine, type 3; deiodinase, iodothyronine type III [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Type III iodothyronine deiodinase (Type-III 5'-deiodinase) (Type 3 DI) (DIOIII) (5DIII) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] deiodinase, iodothyronine, type III [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] type III iodiothyronine deiodinase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Type III iodothyronine deiodinase OS=Rattus norvegicus GN=Dio3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	278 amino acids
Gene Ontology:
Cellular Component:	endosome [IEA] integral to membrane [IEA] endosome membrane [IEA] cellular_component [ND] plasma membrane [UNKNOWN][IEA]
Biological Process:	thyroid hormone catabolic process [UNKNOWN] response to hypoxia [IEP] brown fat cell proliferation [IEP] oxidation reduction [IEA] positive regulation of multicellular organism growth [UNKNOWN] hormone biosynthetic process [IEA] thyroid hormone metabolic process [TAS]
Molecular Function:	thyroxine 5'-deiodinase activity [UNKNOWN][TAS] thyroxine 5-deiodinase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRSLLLHSL RLCAQTASCL VLFPRFLGTA FMLWLLDFLC IRKHFLRRRH PDHPEPEVEL  60
   61 NSEGEEMPPD DPPICVSDDN RLCTLASLKA VWHGQKLDFF KQAHEGGPAP NSEVVRPDGF 120
  121 QSQRILDYAQ GTRPLVLNFG SCTUPPFMAR MSAFQRLVTK YQRDVDFLII YIEEAHPSDG 180
  181 WVTTDSPYVI PQHRSLEDRV SAARVLQQGA PGCALVLDTM ANSSSSAYGA YFERLYVIQS 240
  241 GTIMYQGGRG PDGYQVSELR TWLERYDEQL HGTRPRRL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: IOD3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: