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Protein Overview: KPYM_RAT

General Information:
Name(s) found: KPYM_RAT [Swiss-Prot]
Description(s) found:
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  • pir||B26186 pyruvate kinase (EC 2.7.1.40) isozyme M1 - rat [NCBI NR]
  • gi|56929|emb|CAA33799.1| unnamed protein product [Rattus norvegicus] [NCBI NR]
  • gi|206204|gb|AAB93666.1| M1 pyruvate kinase [Rattus norvegicus] [NCBI NR]
  • gi|16757994|ref|NP_445749.1| pyruvate kinase, muscle [Rattus norvegicus] [NCBI NR]
  • gi|149041864|gb|EDL95705.1| rCG57843, isoform CRA_b [Rattus norvegicus] [NCBI NR]
  • gi|125601|sp|P11980.3|KPYM_RAT RecName: Full=Pyruvate kinase isozymes M1/M2; AltName: Full=Pyruvate kinase muscle isozyme [NCBI NR]
  • Pyruvate kinase PKM OS=Rattus norvegicus GN=Pkm PE=1 SV=3 [Swiss-Prot]
  • pyruvate kinase 3; Pyruvate kinase muscle [HMR_022704-rand.fasta]
  • pyruvate kinase 3 [Rattus norvegicus]gi|56929|emb|CAA33799.1| unnamed protein product [Rattus norvegicus]gi|206204|gb|AAB93666.1| M1 pyruvate kinase [Rattus norvegicus]gi|92715|pir||B26186 pyruvate kinase (EC 2.7.1.40) isozyme M1 - ratgi|125601|sp|P11 [nrdb_11152004_Chlamydomonas]
  • (NM_053297) Pyruvate kinase, muscle; Pyruvate kinase 3 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • Tax_Id=10116 Pyruvate kinase, muscle [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta]
  • Pyruvate kinase isozymes M1/M2 (Pyruvate kinase muscle isozyme) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • pyruvate kinase, muscle [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • rCG57843, isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • unnamed protein product [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • M1 pyruvate kinase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 PYRUVATE KINASE 3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Isoform M1 of Pyruvate kinase isozymes M1/M2 OS=Rattus norvegicus GN=Pkm2 [011711_HMR.fasta]
  • Pyruvate kinase isozymes M1/M2 OS=Rattus norvegicus GN=Pkm2 PE=1 SV=3 [UNIPROT_RAT_07-21-2011_reversed.fasta]
    • Organism: Rattus norvegicus
    Length: 531 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IEA]
    soluble fraction [IDA]
    cytoplasm [UNKNOWN][IEA]
    mitochondrion [UNKNOWN]
    flagellum [UNKNOWN]
    Biological Process: pyruvate biosynthetic process [IDA]
    response to organic substance [IEP]
    response to muscle inactivity [IEP]
    glycolysis [UNKNOWN][IDA]
    response to nutrient [IEP]
    glucose metabolic process [IDA]
    ATP biosynthetic process [IDA]
    skeletal muscle tissue regeneration [IDA]
    response to gravity [IEP]
    response to hypoxia [IEP]
    response to insulin stimulus [IEP]
    liver development [IDA]
    organ regeneration [IDA]
    programmed cell death [UNKNOWN]
    Molecular Function: nucleotide binding [IEA]
    magnesium ion binding [IEA]
    pyruvate kinase activity [UNKNOWN][IDA]
    ATP binding [IEA]
    protein binding [UNKNOWN]
    potassium ion binding [IEA]
    ADP binding [IDA]
    transferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKPDSEAGT AFIQTQQLHA AMADTFLEHM CRLDIDSAPI TARNTGIICT IGPASRSVEM  60
   61 LKEMIKSGMN VARLNFSHGT HEYHAETIKN VRAATESFAS DPILYRPVAV ALDTKGPEIR 120
  121 TGLIKGSGTA EVELKKGATL KITLDNAYME KCDENILWLD YKNICKVVEV GSKIYVDDGL 180
  181 ISLQVKEKGA DYLVTEVENG GSLGSKKGVN LPGAAVDLPA VSEKDIQDLK FGVEQDVDMV 240
  241 FASFIRKAAD VHEVRKVLGE KGKNIKIISK IENHEGVRRF DEILEASDGI MVARGDLGIE 300
  301 IPAEKVFLAQ KMMIGRCNRA GKPVICATQM LESMIKKPRP TRAEGSDVAN AVLDGADCIM 360
  361 LSGETAKGDY PLEAVRMQHL IAREAEAAVF HRLLFEELAR ASSQSTDPLE AMAMGSVEAS 420
  421 YKCLAAALIV LTESGRSAHQ VARYRPRAPI IAVTRNPQTA RQAHLYRGIF PVLCKDAVLD 480
  481 AWAEDVDLRV NLAMNVGKAR GFFKKGDVVI VLTGWRPGSG FTNTMRVVPV P

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle