Protein Overview: TF2H2_RAT

General Information:
Name(s) found:	TF2H2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|34853502\|ref\|XP_215466.2\| PREDICTED: similar to TFIIH basal transcription factor complex p44 subunit (Basic transcription factor 2 44 kDa subunit) (BTF2-p44) (General transcription factor IIH polypeptide 2) [Rattus norvegicus] [NCBI NR] gi\|182701382\|sp\|A0JN27.1\|TF2H2_RAT RecName: Full=General transcription factor IIH subunit 2; AltName: Full=General transcription factor IIH polypeptide 2; AltName: Full=TFIIH basal transcription factor complex p44 subunit; AltName: Full=Basic transcriptio [NCBI NR] gi\|116812559\|ref\|NP_001070896.1\| general transcription factor IIH, polypeptide 2 [Rattus norvegicus] [NCBI NR] gi\|116487735\|gb\|AAI26098.1\| General transcription factor IIH, polypeptide 2 [Rattus norvegicus] [NCBI NR] gi\|109465854\|ref\|XP_001062050.1\| PREDICTED: similar to TFIIH basal transcription factor complex p44 subunit (Basic transcription factor 2 44 kDa subunit) (BTF2-p44) (General transcription factor IIH polypeptide 2) [Rattus norvegicus] [NCBI NR] General transcription factor IIH subunit 2 OS=Rattus norvegicus GN=Gtf2h2 PE=1 SV=1 [Swiss-Prot] similar to general transcription factor IIH polypeptide 2 [HMR_022704-rand.fasta] similar to general transcription factor IIH polypeptide 2 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Similar to general tranScription factor IIH polypeptide 2 [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] General transcription factor IIH subunit 2 (General transcription factor IIH polypeptide 2) (TFIIH basal transcription factor complex p44 subunit) (Basic transcription factor 2 44 kDa subunit) (BTF2-p44) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] General transcription factor II H, polypeptide 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] general transcription factor II H, polypeptide 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SIMILAR TO GENERAL TRANSCRIPTION FACTOR IIH POLYPEPTIDE 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] general transcription factor IIH, polypeptide 2 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] General transcription factor II H, polypeptide 2 (predicted) [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Gtf2h2 General transcription factor IIH subunit 2 [rat-ipi-250309-contam.fasta] General transcription factor IIH subunit 2 OS=Rattus norvegicus GN=Gtf2h2 [011711_HMR.fasta] General transcription factor IIH subunit 2 OS=Rattus norvegicus GN=Gtf2h2 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	396 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] holo TFIIH complex [UNKNOWN][ISS] intracellular [IEA] nucleoplasm [UNKNOWN]
Biological Process:	DNA repair [IEA] nucleotide-excision repair, DNA damage removal [UNKNOWN] transcription from RNA polymerase II promoter [UNKNOWN][ISS] G-protein coupled receptor internalization [UNKNOWN] regulation of transcription [IEA] transcription initiation from RNA polymerase II promoter [UNKNOWN] RNA elongation from RNA polymerase II promoter [UNKNOWN]
Molecular Function:	DNA-dependent ATPase activity [UNKNOWN][ISS] zinc ion binding [IEA] protein binding [UNKNOWN] RNA polymerase II carboxy-terminal domain kinase activity [UNKNOWN][ISS] metal ion binding [IEA] protein N-terminus binding [UNKNOWN] protein kinase activity [UNKNOWN][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEEPERTKR WEGGYERTWE ILKEDESGSL KATIEDILFK AKRKRVFEHH GQVRLGMMRH  60
   61 LYVVVDGSRT MEDQDLKPNR LTCTLKLLEY FVEEYFDQNP ISQIGIIVTK SKRAEKLTEL 120
  121 SGNPRKHITS LKKAVDMTCH GEPSLYNSLS MAMQTLKHMP GHTSREVLII FSSLTTCDPS 180
  181 NIYDLIKTLK TAKIRVSVIG LSAEVRVCTV LARETGGTYH VILDETHYKE LLARHVSPPP 240
  241 ASSGSECSLI RMGFPQHTIA SLSDQDAKPS FSMAHLDNNS TEPGLTLGGY FCPQCRAKYC 300
  301 ELPVECKICG LTLVSAPHLA RSYHHLFPLD AFQEIPLEEY KGERFCYGCQ GELKDQHVYV 360
  361 CTVCRNVFCV DCDVFVHDSL HCCPGCVHKI PTQSGV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: TF2H2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: