Protein Overview: TGFI1_RAT

General Information:
Name(s) found:	TGFI1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	ref\|XP_341935.1\| transforming growth factor beta 1 induced transcript 1 [Rattus norvegicus] [NCBI NR] gi\|150416157\|sp\|Q99PD6.2\|TGFI1_RAT RecName: Full=Transforming growth factor beta-1-induced transcript 1 protein; AltName: Full=Hydrogen peroxide-inducible clone 5 protein; Short=Hic-5; AltName: Full=Androgen receptor-associated protein of 55 kDa [NCBI NR] gi\|149067636\|gb\|EDM17188.1\| transforming growth factor beta 1 induced transcript 1, isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|109462944\|ref\|XP_001079262.1\| PREDICTED: similar to transforming growth factor beta 1 induced transcript 1 [Rattus norvegicus] [NCBI NR] gi\|109459411\|ref\|XP_341935.3\| PREDICTED: similar to transforming growth factor beta 1 induced transcript 1 [Rattus norvegicus] [NCBI NR] Transforming growth factor beta-1-induced transcript 1 protein OS=Rattus norvegicus GN=Tgfb1i1 PE=1 SV=2 [Swiss-Prot] transforming growth factor beta 1 induced transcript 1 [HMR_022704-rand.fasta] transforming growth factor beta 1 induced transcript 1 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Transforming growTh facTor beTa 1 induced TranscripT 1 [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Transforming growth factor beta-1-induced transcript 1 protein (Hydrogen peroxide-inducible clone 5 protein) (Hic-5) (Androgen receptor-associated protein of 55 kDa) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] transforming growth factor beta 1 induced transcript 1, isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] PREDICTED: similar to transforming growth factor beta 1 induced transcript 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 TRANSFORMING GROWTH FACTOR BETA 1 INDUCED TRANSCRIPT 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Tgfb1i1 Transforming growth factor beta-1-induced transcript 1 protein [rat-ipi-250309-contam.fasta] Transforming growth factor beta-1-induced transcript 1 protein OS=Rattus norvegicus GN=Tgfb1i1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	461 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] cytoskeleton [IEA] focal adhesion [UNKNOWN][TAS] cytoplasm [IEA] nuclear matrix [IEA] cell junction [IEA] intracellular [UNKNOWN]
Biological Process:	positive regulation of epithelial to mesenchymal transition [UNKNOWN] epithelial cell differentiation [UNKNOWN] ubiquitin-dependent SMAD protein catabolic process [UNKNOWN] response to heat [IDA] cell fate commitment [UNKNOWN] cell differentiation [IEA] negative regulation of fat cell differentiation [UNKNOWN] Wnt receptor signaling pathway [IEA] positive regulation of transcription [UNKNOWN] morphogenesis of embryonic epithelium [UNKNOWN] negative regulation of transforming growth factor beta receptor signaling pathway [UNKNOWN] positive regulation of transforming growth factor beta receptor signaling pathway [UNKNOWN]
Molecular Function:	Roundabout binding [UNKNOWN] zinc ion binding [IEA] protein binding [UNKNOWN][IPI] transcription coactivator activity [UNKNOWN] androgen receptor binding [UNKNOWN] metal ion binding [IEA] I-SMAD binding [UNKNOWN][IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDLDALLSD LETTTSHMSR LGAPKERPPE TLTPPPPYGH QPQTGSGESS GASGDKDHLY  60
   61 STVCKPRSPK SVAPVAPPFS SSSGVLGNGL CELDRLLQEL NATQFNITDE IMSQFPSSKM 120
  121 AEGEGKEDQS EDKSITTVPS STFPAPSKPS ATSATQELDR LMASLSDFRV QNHLPASGPP 180
  181 QPPAVSPTRE GCPSPPGQTN KGSLDTMLGL LQSDLSRRGV PTQAKGLCGS CNKPIAGQVV 240
  241 TALGRAWHPE HFLCRGCSTT LGGSSFFEKD GAPFCPECYF ERFSPRCGFC NQPIRHKMVT 300
  301 ALGTHWHPEH FCCVSCGEPF GEEGFHEREG RPYCRRDFLQ LFAPRCQGCQ GPILDNYISA 360
  361 LSALWHPDCF VCRECLAPFS GGSFFEHEGR PLCENHFHAQ RGSLCATCGL PVTGRCVSAL 420
  421 GRRFHPDHFT CTFCLRPLTK GSFQERASKP YCQPCFLKLF G

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: TGFI1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: