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Protein Overview: CG1732-PB

General Information:
Name(s) found: CG1732-PB / FBpp0088909 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG1732 (CG1732, FBgn0039915). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:650319..655978. It has the cytological map location 102D1. Based on sequence similarity, it is predicted to have molecular function</span>: gamma-aminobutyric acid:sodium symporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: neurotransmitter transport. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 508 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [IEA]
    Biological Process: neurotransmitter transport [IEA]
    Molecular Function: neurotransmitter:sodium symporter activity [IEA]
    gamma-aminobutyric acid:sodium symporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYTNSASDGD GGGDVCKHES IEMSKELGHT TSLQSSSPTT TDTSNKQQLV KIEQLPDRGS  60
   61 WSSKMDFILS VVGLAIGLGN VWRFPYLCYK NGGGAFILPY IITLFLAGIP MFFMELALGQ 120
  121 MLTIGGLGVF KIAPIFKGIG YAAAVMSCWM NVYYIVILAW AVFYFFMSMR ADVPWRTCNN 180
  181 WWNTVNCVSQ YERKNLHCWD KIINGTTQKV CSVSALNITS LELTDPVKEF WERRALQISH 240
  241 GIEEIGNIRW ELAGTLLLVW ILCYFCIWKG VKWTGKVVYF TALFPYVLLT ILLVRGITLP 300
  301 GALEGIKFYI IPNFSKLTNS EVWIDAVTQI FFSYGLGLGT LVALGSYNKF TNNVYKDALI 360
  361 VCTVNSSTSM FAGFVIFSVI GFMAHEQQRP VADVAASGPG LAFLVYPSAV LQLPGSPMWS 420
  421 CLFFFMLLLI GLDSQFCTME GFITAIIDEW PQLLRKRKEI FIAIVCALSY LVGLTCITQL 480
  481 AAFAYCGSYS LNVFQYLGAM EWIDFMTE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..508] PSI-BLAST 51.39794 Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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