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Protein Overview: CG3744-PA, CG3744-PC

General Information:
Name(s) found: CG3744-PC / FBpp0084102 [FlyBase]
CG3744-PA / FBpp0084100 [FlyBase]
Description(s) found:
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  • gi|45553511|ref|NP_996292.1| CG3744, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|45550825|ref|NP_651304.2| CG3744, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|45446649|gb|AAS65214.1| CG3744, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|45446648|gb|AAF56357.2| CG3744, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|25012282|gb|AAN71254.1| LD33755p [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG3744 (CG3744, FBgn0039240). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:20697503..20702366. It has the cytological map location 96B2. Based on sequence similarity, it is predicted to have molecular function</span>: dipeptidyl-peptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis. 8 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • (AAF56357) CG3744-PA [DrosMelano7227.FASTAC.txt]
  • CG3744-PC, isoform C [Drosophila melanogaster]gi|45446648|gb|AAF56357.2| CG3744-PA, isoform A [Drosophila melanogaster]gi|45553511|ref|NP_996292.1| CG3744-PC [Drosophila melanogaster]gi|45550825|ref|NP_651304.2| CG3744-PA [Drosophila melanogaster]gi|2 [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(20697674..20697875,20697941..20698133,20698376..20698598,20698660..20699004,20699081..20699684,20699825..20700381,20700436..20700655,20700715..20701247,20701428..20701712); ID=FBpp0084102; name=CG3744-PC; parent=FBgn0039240 [fly-100309-contam.fasta]
  • type=protein; loc=3R:complement(20697674..20697875,20697941..20698133,20698376..20698598,20698660..20699004,20699081..20699684,20699825..20700381,20700436..20700655,20700715..20701247,20701428..20701712); ID=FBpp0084100; name=CG3744-PA; parent=FBgn0039240 [fly-100309-contam.fasta]
  • LD33755p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG3744-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG3744-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(20697674..20697875,20697941..20698133,20698376..20698598,20698660..20699004,20699081..20699684,20699825..20700381,20700436..20700655,20700715..20701247,20701428..20701712); ID=FBpp0084102; name=CG3744-PC; parent=FBgn0039240,FBtr0084727; dbxref=FlyBase:FBpp0084102,FlyBase_Annotation_IDs:CG3744-PC,GB_protein:AAS65214.1,REFSEQ:NP_996292,GB_protein:AAS65214; MD5=6a534d5753578f5cc3e9026857b6b8b3; length=1053; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(20697674..20697875,20697941..20698133,20698376..20698598,20698660..20699004,20699081..20699684,20699825..20700381,20700436..20700655,20700715..20701247,20701428..20701712); ID=FBpp0084100; name=CG3744-PA; parent=FBgn0039240,FBtr0084725; dbxref=GB_protein:AAF56357.1,FlyBase:FBpp0084100,FlyBase_Annotation_IDs:CG3744-PA,GB_protein:AAF56357.2,REFSEQ:NP_651304,GB_protein:AAF56357; MD5=6a534d5753578f5cc3e9026857b6b8b3; length=1053; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(20697674..20697875,20697941..20698133,20698376..20698598,20698660..20699004,20699081..20699684,20699825..20700381,20700436..20700655,20700715..20701247,20701428..20701712); ID=FBpp0084102; name=CG3744-PC; parent=FBgn0039240,FBtr0084727; dbxref=FlyBase:FBpp0084102,FlyBase_Annotation_IDs:CG3744-PC,GB_protein:AAS65214.1,REFSEQ:NP_996292,GB_protein:AAS65214; MD5=6a534d5753578f5cc3e9026857b6b8b3; length=1053; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3R:complement(20697674..20697875,20697941..20698133,20698376..20698598,20698660..20699004,20699081..20699684,20699825..20700381,20700436..20700655,20700715..20701247,20701428..20701712); ID=FBpp0084100; name=CG3744-PA; parent=FBgn0039240,FBtr0084725; dbxref=GB_protein:AAF56357.1,FlyBase:FBpp0084100,FlyBase_Annotation_IDs:CG3744-PA,GB_protein:AAF56357.2,REFSEQ:NP_651304,GB_protein:AAF56357; MD5=6a534d5753578f5cc3e9026857b6b8b3; length=1053; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG3744, isoform A OS=Drosophila melanogaster GN=CG3744-RC PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(20697674..20697875,20697941..20698133,20698376..20698598,20698660..20699004,20699081..20699684,20699825..20700381,20700436..20700655,20700715..20701247,20701428..20701712); ID=FBpp0084102; name=CG3744-PC; parent=FBgn0039240,FBtr0084727; dbxref=FlyBase:FBpp0084102,FlyBase_Annotation_IDs:CG3744-PC,GB_protein:AAS65214.1,REFSEQ:NP_996292,GB_protein:AAS65214; MD5=6a534d5753578f5cc3e9026857b6b8b3; length=1053; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(20697674..20697875,20697941..20698133,20698376..20698598,20698660..20699004,20699081..20699684,20699825..20700381,20700436..20700655,20700715..20701247,20701428..20701712); ID=FBpp0084100; name=CG3744-PA; parent=FBgn0039240,FBtr0084725; dbxref=GB_protein:AAF56357.1,FlyBase:FBpp0084100,FlyBase_Annotation_IDs:CG3744-PA,GB_protein:AAF56357.2,REFSEQ:NP_651304,GB_protein:AAF56357,FlyMine:FBpp0084100,modMine:FBpp0084100; MD5=6a534d5753578f5cc3e9026857b6b8b3; length=1053; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • CG3744, isoform A OS=Drosophila melanogaster GN=CG3744-RC PE=2 SV=2 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
    • Organism: Drosophila melanogaster
    Length: 1053 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    Biological Process: proteolysis [IEA]
    Molecular Function: dipeptidyl-peptidase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESRTQMNQS NQQQQQQRNR LPSSPSPPLS VVSLTGGPNA NTTLMGLEHD AVPSSQLGRN  60
   61 NNNGGGHHRS HSITNAATTS LANLLDGFTA RVSTAAAAAA ATATTTEVVV AAASVITNHL 120
  121 SSPTSGTPPH GLDVDEGDDE CDDCEEDEDD PVDNDGHIAA PTPNKSWAEN KQVVQEIRKK 180
  181 MCNLSSMVPT NVQFRHLSDG RARCYFLGTP PQSWETTLLF ADINLTQSEE QQLLVQRLEG 240
  241 IASDEWSPTM NAGSPTSSGH QPAFLFNSLP RPRLPWSPLL QQPIQSSGGS GGSGSASPYA 300
  301 REYQLLQERK RLSTWGITSY ELHKPSGKLV FPCFNDLYQC LDTGYNSGLL FPTQLRTCPQ 360
  361 WTALDPQICP QNSDMIAYIS DCDLFVTHTL SGHEKRLTYT STGRHSYVDD ALSAGVPSYV 420
  421 MQEEFSRYQG FWWQPHSNDG IYRIVYEEVD ESEVSVYTFP SSTAMHGRVD EYRFPRTGSP 480
  481 NAKSKLKLVQ FVLNEALQVS EIAIKDLPYS LLAVFSWLEY IVRVGWTPDA KYVWVQGLDR 540
  541 KQQRLDVILI PLDNFCESYS SQVSTPTDSI GDHSWRSLYS RTITPLQVIY TERSDSWINV 600
  601 HDMLHFLDLT ETSVTFLWAS EETGFRHLYL VTASLLLSQA NGQPDPGSVG AQPSFVDLSA 660
  661 LQPRILNKVA LTSGEWEVLA RNLWVDKANK LVYFVGLRDT PLEKHLYVVS LERPEHIRLL 720
  721 TEPGYSYLVE FDDHFNDLFP IFSQQCKLML LVYCNIQRLP SCKVMRVNQT CSNGGVNGIQ 780
  781 ISLVGYLHEG GKPEPQYCPQ IFSPQLPSGD IVYAMVFKPH NFELGVKYPT VLNVYGGPEV 840
  841 QTVNNTFKGK HQLRMHMLAA QGYCVICIDS RGSRHRGKRF ESHIRGRMGQ VELTDQVDAL 900
  901 RSLSDQLGYI DMDRVAIHGW SYGGYLSLMG LVQYPKIFKV AIAGAPVTNW EYYDTGYTER 960
  961 YMDMPQNNEA GYSAGSVLEY VNSFPEEDKR LLLIHGLIDE NVHFCHTSRL ISALNKANKP1020
 1021 YEVHLFPEER HSLRNLESNK NYETKLLSFL QNL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..213] PSI-BLAST 43.522879 TolB, C-terminal domain; TolB, N-terminal domain
    2 View Details [214..1053] PSI-BLAST 81.39794 Structure of a human A-type Potassium Channel Accelerating factor DPPX, a member of the dipeptidyl aminopeptidase family

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • peptidase activity
    		•  2.95454401715363 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.49887769458268 bayes_pls_golite062009
  • hydrolase activity
    		•  1.89423502987436 bayes_pls_golite062009
  • dipeptidyl-peptidase activity
    		•  1.57239255137232 bayes_pls_golite062009
  • binding
    		•  1.39533211155749 bayes_pls_golite062009
  • exopeptidase activity
    		•  1.36397817334992 bayes_pls_golite062009
  • catalytic activity
    		•  1.00900109067915 bayes_pls_golite062009
  • protein binding
    		•  0.539004739446168 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle