YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: Bruce-PA

General Information:
Name(s) found: Bruce-PA / FBpp0081717 [FlyBase]
Description(s) found:
Found 21 descriptions.
SHOW ALL
  • The gene Bruce is referred to in FlyBase by the symbol Dmel\Bruce (CG6303, FBgn0037808). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:6138366..6157071. It has the cytological map location 86A7-86A8. Based on sequence similarity, it is predicted to have molecular function</span>: ubiquitin-protein ligase activity. There is experimental evidence that it is involved in the biological process</span>: spermatid development; programmed cell death. 16 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 4876 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: regulation of protein metabolic process [IEA]
    sperm individualization [NAS]
    anti-apoptosis [ISS]
    spermatid development [IMP]
    programmed cell death [IGI]
    post-translational protein modification [IEA]
    Molecular Function: ubiquitin-protein ligase activity [ISS]
    small conjugating protein ligase activity [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATEQHHQQR VLKQDGYLDL GDCNSAPSRP FEMRNVVYHP QLNVLLLFDN GSTVKVLDAN  60
   61 SGVILQTYHL SSNGDSIVHG RYMPLQDKIL FWDGHNLGLR GDYNGVLLLD TILQAPIGQN 120
  121 DDYIKLEIIL SEAIIFQNCI TELESEGLEC PCDISNELTQ KINQAQLKAK KGIKAQRWNT 180
  181 ICLEVPYSSL KLVSNNMVIL LKRLERHIPV LAIASAINER LTDMMMGSRV PDFGWNFSNF 240
  241 QRVLMHSEAV RRQTFEKWPH MDYKWALPDQ MAQAGFYHQP SSSGEDRAMC FTCSVCLVCW 300
  301 EKTDEPWSEH ERHSPLCPFV KGEYTQNVPL SITYATNPAL PAPGLGFDII SNSDYANVLC 360
  361 TSCSQTGELS VWSIERHLKL MHTFHVPTLL NYIFEESFEW ARVTAICVLP NARARTKVNY 420
  421 VYSAANYGGS GSSNGAGCNS GLNAVSGGKF GSVNAQHITS TSTLRAGVVG SKIVLGVSVR 480
  481 QSSGELALRM VVLNIVEVDR NSESSTSVSN DSGSVSSGGG QLMKSSSPMV NVSAENNATV 540
  541 TQVNLESKDD DNKAMTPYEK FADGFDSNGF VSALMTYNKN NGVSQNTDDA SALYDFDLCT 600
  601 LSQILDHNLE EPLSLMVGSS NTVNVSNIGM GNEINKLVVD VEISHQNNNN NNNNNNEASS 660
  661 LGGNSSNNNN NIMINGGTNS SIDKMTAIEE IDCVVESWTS VKRMNALDGA SSGVNGVNHM 720
  721 DQEVIEIAEI LPTTPKCNQL LVKLLRTKAP EAEGSKIIMA TVAKEEEEED EEQRTDESME 780
  781 TDNNAEGNVA AQLLVFDYDD TEISNDYTLA MTFSRAKFPK QLCILPHFNS SPEHKDAGSI 840
  841 CVVCADGTVE IYSLADFQGT MVIEEEGEHF ESVVYCRNLD RLCCCSRQGG LLFYSLSDGE 900
  901 NDSGDELLEM DDDCSTTLTQ AADVSVTDGG RQLARTDLLG KTLLANESIC MDAGSEAAAI 960
  961 PNSSSAAQGA HVQTSPSASS APSTNANLLA YKTADLTLED LKVFYALTQF DDKLTVYSAE1020
 1021 VPSCWNDIGQ VQNQRKQSQN MRHGGDERDF TRTWRLHNDA TTWDEHIIEL NLAQPVSLGH1080
 1081 IDLKFTVYQQ CSNPAAIQVT LLKQNNNGFG YRMKGPHSSY KPNVIDDNID LSYIANENPV1140
 1141 LSEEYLLAHN AEVLAGPIEL SSCIDLCDQG GTATLTSPKL FKTRTRNFLL HIKTVSDPSK1200
 1201 DGQNKTRGCD WLHEISISVR AVKSHSRISN GRMQRIAMLE SNVLLVQLLR IASDPASSSL1260
 1261 AKNLSLDILN WICFIRLNRF RSPKSERLKD QINKQTAANI QDLLAQQFEC ISLAEKHIEQ1320
 1321 LLRNCVIYSE RSTAHKCVKL LIMLTEGATN LPAEVQDHTT LDYSFKAAIA NTFPELPRAQ1380
 1381 CGSVVRWYMM LTCATSTAES HNSISEQAIS LLKEIAAEID KRWDPHCALL CTRFGLYGYP1440
 1441 FEPEIFDFDF PNVSRQGPGS SVANVIRSSP TILPVTGLDI KRLSSIDGVD FRTFPYLIRG1500
 1501 KSISNQLRGL LEVVQLHFNC VQTSEATRID NIDSVGGNTG ANVIIEDVMM MPKQVVAKEK1560
 1561 GEEMLNDLVN DVECLVEEMK VDENEKQEKV DYDAFGLVNG FKDKTLSSLN SVKQTLKEEV1620
 1621 KKEKADIMDK LTIAKFLPKL SLLESYMQKK INEHISFDDF GKLDNWDGNT TPPFNLEVEA1680
 1681 PIVCSEATSE SNMSQQATSA GGNILDDAAD SEKITESLNA NPCQPIAWHK LITPPPKQMI1740
 1741 VIDRMHSGAR RFVVLDFGQH ILLTDLVIPS CDELTSLNID IWCFDEETDC TRLVQVNDIQ1800
 1801 TKTLVLSDIQ PAPICRYLKL TIIGRIGMSA TKCKVPLGRF FGHPVVLEHD GYGDQLMKYI1860
 1861 KHPTHSLQSQ IKSLNALYED VHCRYSLASS KLMDLLAPMR NSELSNVAHL QAFINKQREE1920
 1921 ELSGLENNNK VVSLYDECML LQYQINVIRN VVLRLERALS PNSPTTTLLP GQSIPLTEDI1980
 1981 LRAASRDKLR VLSLSLVEVL LHFSIEYGIK NILPVHQRFN AATAKALFNA LVVYGDAQLQ2040
 2041 LATCSLLVRM CCFQPWWGDF LADTFCSLFS AQNCKAFPQD RIFFLLTYLG RRSIAMGACR2100
 2101 SIVIDAVLKT LVKLLAPISP HYKFQSEQPS TSANAADRNA AMGTTSDLQL ITWLLLFLSV2160
 2161 CLDDNERKDK SAARWDFMSC EGDFTKARPS ATPNIKQLRC FKKRIIQQNK YLAQPYADWG2220
 2221 KKIYMIQNEH PGIFMELSTK SKGAGPTKST STGGKINMGS SGLCVGGPSS SSGNTSKSAA2280
 2281 SSSSPKNQAV PGTDGERDSN FDKGLKSLRM DNIKVVIRGL FALLLEMDFD CNMDQFLLTC2340
 2341 KVIARLVAAC RPSVQLCKIV TIAQLQQLVR LSVWNDQQHP WAVHAITCLL QDLLDADKQF2400
 2401 RDNDVTPTND TPRTMEAAIQ ETRDLFSDYT STASSCTEAL FETLMPTARE FYQEAVKYNY2460
 2461 LPSLIECDDT EFDEMLNDID MIERTKPVTK KESNALSKNT FNFFCKSISI ALDSRLDVGL2520
 2521 ELHVETQLRR LTNRTSLDLY SSLPQVLTNE FVSPPPEAAP WPEYLTQLWS GTEYNGDNTY2580
 2581 VMFKRVFDSI LAELHLEDTW VHLEQVLQMW LTLNCELSDK PYTSGITHSD VPKIPFGANA2640
 2641 VQGLLLALAW HSDIKLRTWC LGFQCLFLAC NSLPIGDDAD CTRINEAIVN DENFEKVLLR2700
 2701 FFSGYGMSSS IITNRCAGPT ICKHLHELLL WLHSKSETSG IPCKRRLKDI LLHVVLQLVQ2760
 2761 PGGSISNQQG PIDAQNQLVR DLLMMPNDKG DLNIALKITE SVSFLVYNNI SNGERLQCQR2820
 2821 GNENSPVGNN FSNLFANVLG SENPNKQNAA ICDNSLIINL LKLSSHMVLT EMPRQPSEVT2880
 2881 IPEEEELSNQ SQTDETKAEQ LNTEGHRSKV PCIADWVLRH FPTMKRLFGT LSQCSTNTFT2940
 2941 MMSSGCFFSP KSNMILDDPQ TIADAVFSLM ITLNDKASHP RLVVVPICRY LEETTIPRNA3000
 3001 TLPRLPHSEP FLWYISKVLE VPAAVQTFTQ LGGIQIICHS LVRLNKTIIN MQPGLISLIM3060
 3061 QHLTRNTRFK RNNHVAASSA CKKTTTGTGT TCPTSAQPPR SAAQYDGLIN FAPFSHIVSE3120
 3121 NDATQSAEVL ISNPNNSHRR PRSPAWTYMF YPNETHVDLT ITLPTAILLK EVQLVPHTTS3180
 3181 LASCPSAVAL ELSRDYGLGS IPVGAPMATT GLTCIRLKLA KAEVATSIVL RLYKPKDCGN3240
 3241 VGLVQIAVLG QTIFGNRMHG LRSPSPFIDS LATCSSPVQT AVLAAMDADS MLEDDAFAKT3300
 3301 SIGWVRILSR CFHVAALQPD SKLADLIAAY PAAYPGFLEA CCSLLNIMPM IPSLAQQHLE3360
 3361 TILLKLSAYN HEISLQLLRT LLWHTTPQVF KLSSDSVCDL IYEVVTGSTE HLLDKLRVLI3420
 3421 DWVMQLHDNY SKQARCNNPQ SGFVKVIASI LWKVHTQQQL PELPLLISSS LFETCFEWVS3480
 3481 SLEHDEPLKS SFDSLLCALC FIKPELFNQL LVKLGVKLEP PARGQTDDSK VQSGSAWFRR3540
 3541 EGSENLSVLL QRPTFLKTLA LACQSPAAVY QMLDSGLPKL LAHAIYEYCM HLMPGSEPVA3600
 3601 SASTVPEDEP LANNQAAAAA DDEDSSLTDF DKAEANVVYN TPLLSSSNVP KVLDFFAECC3660
 3661 AEGPMRDWLG TMQGSVFWKP LLQLLCNTHA AQFSKTLPKE QSFIRLERAT INFFTRVSAC3720
 3721 HPGNQENLTS LLIGAIICKP LRFSHGVRPT ISGFTRQMVL QLLLENEHIT VSVRSQQPLQ3780
 3781 RRDTLSAVLG GISSGASTSL PVAAVNNHPA RRSSAHHMLF TVTTSTTCQE IMQNCVSVFS3840
 3841 NLVYQQPTDQ RAGETSASSS GVSSATAKSS ESKMEKSSFL NFNNVEAGSM EFLTVGAAVA3900
 3901 AKDKRIKDAK NQAAMNKDKE TQTSSTNLAS NIFNVDEFLL QSANAVNGNQ LVIPEYSDIV3960
 3961 LAGDATISQV LASLQNAGHS LSTPCISFDL VLQQRSDDTS EAKKTKAACT EPLPSPLQRF4020
 4021 SSSGGLSLLA HYLPTVYPEH SGRKTTLVFS EKEKSPPLSD WVKLEPNDEI YEDLEDTLCE4080
 4081 PAAKLATVSS VPQHSLAAFG LFLRLPAYSD VLLRDKMRAQ CLLRLVLGVT GDGDGNDIYS4140
 4141 LSLAPSLPTL PFEVFRQLLD SVPLSTDDGV LLRRVVIEVG AMHLVLNCLG IFSHQSHNNR4200
 4201 IGAPISEPSP SGTSSGSGTI GNGSGNGSVS GTKTNAPEEA TPSATSDDKS HMYWAKGTGF4260
 4261 GTGSTTQSWN VEQALLRQKS EEEHVTVLLL VLASYINPGD CIPSEMCGED ILAYHDVRDV4320
 4321 TGELPPIFQT LLQQSCLIPA LSSYLRNDSV LDITRHIPLY RAILKLLRAL SLSKMLVSLL4380
 4381 QPSASGSGDS TPPIVELLTS MKTCVDTYAK RLKVNKKSNI KGQTHQLTFN IDDGDDEGLA4440
 4441 LLIPDIHETS VLVQKTTDAD ALINMLHTNE DGSAQLEPQS KSIEQRYLEL MKKRQFDTFD4500
 4501 MIVESDNNSF RFVVSHHFEK MVRLAGDRYH PSRVKRLAQE AVTLSTSLPL SFSSSVFVRC4560
 4561 DTDRLDIMKV LITGPADTPY ANGCFEFDVF FPPDYPNQPM LINLETTGRH SVRFNPNLYN4620
 4621 DGKVCLSVLN TWHGRPEEKW NAQTSSFLQV LVSIQSLILV PEPYFNEPGF ERSRGSPSGT4680
 4681 NSSREYNSNI YQACVRWAML EQIRSPSQCF KDVIHKHFWL KREEICAQIE GWIEELGKPQ4740
 4741 YTERASRTIS FNSMVLRRHY RHLREELSKL KPPRGLEDLD APFNPVATLP PMDVSAVAPS4800
 4801 LAATNTVQAQ PDDAIVTDIT LLGENADECE ADGDAEGDGE VDDGFKGFPQ EEGLLTGEEE4860
 4861 VVEILSDTEN ESSMWQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle