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Protein Overview: Antp-PD, Antp-PN

General Information:
Name(s) found: Antp-PD / FBpp0089241 [FlyBase]
Antp-PN / FBpp0089086 [FlyBase]
Description(s) found:
Found 30 descriptions.
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  • The gene Antennapedia is referred to in FlyBase by the symbol Dmel\Antp (CG1028, FBgn0260642). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2721975..2824950. It has the cytological map location 84A6-84B2. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: heart development; specification of segmental identity, antennal segment; lymph gland development. 147 alleles are reported. The phenotypes of these alleles are annotated with 61 unique terms, many of which group under: adult segment; peripheral nervous system; adult external prothorax; adult mesothoracic segment; antennal segment; organ system; nervous system; humeral trabecule; primordium; imaginal precursor. It has 11 annotated transcripts and 11 annotated polypeptides. [FlyBase]
  • The gene Antennapedia is referred to in FlyBase by the symbol Dmel\Antp (CG1028, FBgn0260642). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2721975..2824950. It has the cytological map location 84A6-84B2. It is reported to have molecular function</span>: specific RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: heart development; specification of segmental identity, antennal segment; lymph gland development. 147 alleles are reported. The phenotypes of these alleles are annotated with 61 unique terms, many of which group under: adult segment; peripheral nervous system; adult external prothorax; adult mesothoracic segment; antennal segment; organ system; nervous system; humeral trabecule; primordium; imaginal precursor. It has 11 annotated transcripts and 11 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 374 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTMSTNNCES MTSYFTNSYM GADMHHGHYP GNGVTDLDAQ QMHHYSQNAN HQGNMPYPRF  60
   61 PPYDRMPYYN GQGMDQQQQH QVYSRPDSPS SQVGGVMPQA QTNGQLGVPQ QQQQQQQQPS 120
  121 QNQQQQQAQQ APQQLQQQLP QVTQQVTHPQ QQQQQPVVYA SCKLQAAVGG LGMVPEGGSP 180
  181 PLVDQMSGHH MNAQMTLPHH MGHPQAQLGY TDVGVPDVTE VHQNHHNMGM YQQQSGVPPV 240
  241 GAPPQGMMHQ GQGPPQMHQG HPGQHTPPSQ NPNSQSSGMP SPLYPWMRSQ FERKRGRQTY 300
  301 TRYQTLELEK EFHFNRYLTR RRRIEIAHAL CLTERQIKIW FQNRRMKWKK ENKTKGEPGS 360
  361 GGEGDEITPP NSPQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..190] MSA 8.365997 View MSA. No confident structure predictions are available.
    2 View Details [191..295] deduced N/A No confident structure predictions are available.
    3 View Details [296..374] PSI-BLAST 25.30103 DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  2.6809639302471 bayes_pls_golite062009
  • DNA binding
    		•  2.45264254102339 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.32767577674158 bayes_pls_golite062009
  • binding
    		•  2.12643314274039 bayes_pls_golite062009
  • transcription factor activity
    		•  1.9610710007594 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.71974400731667 bayes_pls_golite062009
  • protein binding
    		•  0.57484570028668 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.328460252819506 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.245215140763955 bayes_pls_golite062009
  • transcription activator activity
    		•  0.0177888191364471 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle