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Protein Overview: emp-PB

General Information:
Name(s) found: emp-PB / FBpp0072308 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • The gene epithelial membrane protein is referred to in FlyBase by the symbol Dmel\emp (CG2727, FBgn0010435). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20864127..20872321. It has the cytological map location 60E11. Based on sequence similarity, it is predicted to have molecular function</span>: scavenger receptor activity. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 6 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 551 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [ISS][NAS]
    plasma membrane [NAS]
    lysosome [IEA]
    Biological Process: autophagic cell death [IEP]
    salivary gland cell autophagic cell death [IEP]
    cell adhesion [IEA]
    defense response [NAS]
    Molecular Function: scavenger receptor activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLDDILHIN NCKADCSSLS TTPNPKTDLV NMNGPKHKFC TKLSSTYLRK WWITIVVAAA  60
   61 LIIGGIVVAC EFTVLIDAVV DRMVALRPGA KTFGWWAKPP VEPRISLYIY NVTNADDFLS 120
  121 NGSKAIVDEV GPYVYSETWE KVNIVENDNG TLSYNLRKIY SFREDLSVGP EDDVVIVPNI 180
  181 PMLSATSQSK HAARFLRLAM ASIMDILKIK PFVQVSVGQL LWGYEDPLLK LAKDVVPKEQ 240
  241 KLPYEEFGLL YGKNGTSSDR VTVNTGVDDI RRYGIIDNFN GRTHLPHWTT DACNTLAGTD 300
  301 GSIFPPHIDH DRILHVYDKD LCRLLPLVFE KEVMTSNEVP GYRFTPPEWV FADVDSHPDN 360
  361 MCFCPAGKPS CSPNGLFNVS LCQYDSPIML SFPHFYLADE SLRTQVEGIS PPMKEKHQFF 420
  421 FDVQPKMGTT LRVRARIQIN LAVSQVFDIK QVANFPDIIF PILWFEEGID NLPDEVTDLM 480
  481 RFAEQVPPKI RVALIVGLCA LGVILLLLST FCLIRNSHRQ STLHLEGSNY LATAQVDMNK 540
  541 KQNKDNQPAR Y

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..97] MSA 1.112995 View MSA. No confident structure predictions are available.
    2 View Details [98..170] MSA 4.120981 View MSA. No confident structure predictions are available.
    3 View Details [171..289] MSA 4.135987 View MSA. No confident structure predictions are available.
    4 View Details [290..396] MSA 1.135975 View MSA. No confident structure predictions are available.
    5 View Details [397..551] MSA 6.130985 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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