Protein Overview: nvy-PA

General Information:
Name(s) found:	nvy-PA / FBpp0072174 [FlyBase]
Description(s) found: Found 20 descriptions. SHOW ALL	The gene nervy is referred to in FlyBase by the symbol Dmel\nvy (CG3385, FBgn0005636). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20163260..20178611. It has the cytological map location 60C5-60C6. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: axon guidance; dendrite morphogenesis; bristle morphogenesis; muscle organ development. 11 alleles are reported. The phenotypes of these alleles are annotated with: medial longitudinal fascicle; ventral nerve cord; lateral longitudinal fascicle; mechanosensory sensory organ; embryonic central nervous system; abdominal segmental nerve; abdominal intersegmental nerve. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	743 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][ISS]
Biological Process:	muscle organ development [IMP] bristle morphogenesis [IMP] regulation of transcription, DNA-dependent [IEA][ISS] axon guidance [IMP] dendrite morphogenesis [IMP]
Molecular Function:	transcription factor activity [ISS] zinc ion binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMALDGKAII KEEITDKDAY DAAAAAAAAV AAGAALAVAS AAAVQVPPAS SSSAGSASSA  60
   61 AAAATNNTTS AAATAAAISR RLKASSSGGD KSSTSSSSSK DSSHTSSSRS ERDRERERER 120
  121 ERERDRLCRT PPDSPPDSSR SLAPRSPHSP LQLHQHPQRN ASVSPVVNGS SSGGGGVGSS 180
  181 GTSPTPTPGS QHAASLAAAA AAAAAAHVEQ ARLVSKMRKF LGALVQFSQE LGQPEVCERV 240
  241 RALVLSLCSG SISVEEFRLA LQEAINLPLR PYVVPLLKNS IALVQREILA LARATNQSAL 300
  301 QYVTNNEQAV MEFAPHGVAS AEFGDIFIQL EAPTSNGSSA VFKRRSSDSM MEHGGHNGLQ 360
  361 EWNEYMASGG AGYPPPPSKR LTLHPAHSVV AYGEYGVSSA EGLPSAAAFM QRDERDLRMS 420
  421 EAQARHAAPP QRAGNPQPNP NAAAPGAPGA GGEEEWKNIH TMLNCISAMV DKTKRAITIL 480
  481 QQRGIEPQHP NSGQEVTPAA MAELRRQTEE KVAEFKRNAE DAVTQVKRQA VIEIQRAVVA 540
  541 AETRAAEIMT QERLRMEKFF MEMSRHSSGE RDLDNKSPSM ASAQNGSNLQ QQCWNCGRKA 600
  601 TETCSGCNMA RYCSASCQYR DWDSHHQVCG NTRASELSAK HLHSASNLSL RNAMATRSPP 660
  661 TPNSAAHLQA AAAAAAAAAG AREAVSAPVG GPGAGIAVGT GAGSGGQSGG GGGGGGGGGG 720
  721 GAAAAAVAAA TPGALVANGL GSK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..103]	MSA	3.225989	View MSA. No confident structure predictions are available.
2	View Details	[104..210]	deduced	N/A	No confident structure predictions are available.
3	View Details	[211..315]	FFAS03	2.92	No description for 2pp4A was found.
4	View Details	[316..441]	MSA	3.215988	View MSA. No confident structure predictions are available.
5	View Details	[442..577]	PSI-BLAST	21.522879	The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for AML1-ETO'S activity
6	View Details	[578..674]	PSI-BLAST	22.69897	No description for 2oddA was found.
7	View Details	[675..743]	deduced	N/A	No confident structure predictions are available.

Protein Overview: nvy-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: