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View Structure Prediction Details

Protein: nvy-PA
Organism: Drosophila melanogaster
Length: 743 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nvy-PA.

Description E-value Query
Range
Subject
Range
gi|39644928 - gi|39644928|gb|AAH16298.2| CBFA2T2 protein [Homo sapiens]
333.0 [0..220] [666..1]

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Predicted Domain #1
Region A:
Residues: [1-103]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMALDGKAII KEEITDKDAY DAAAAAAAAV AAGAALAVAS AAAVQVPPAS SSSAGSASSA  60
   61 AAAATNNTTS AAATAAAISR RLKASSSGGD KSSTSSSSSK DSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [104-210]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HTSSSRSERD RERERERERE RDRLCRTPPD SPPDSSRSLA PRSPHSPLQL HQHPQRNASV  60
   61 SPVVNGSSSG GGGVGSSGTS PTPTPGSQHA ASLAAAAAAA AAAHVEQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [211-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARLVSKMRKF LGALVQFSQE LGQPEVCERV RALVLSLCSG SISVEEFRLA LQEAINLPLR  60
   61 PYVVPLLKNS IALVQREILA LARATNQSAL QYVTNNEQAV MEFAP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.92
Match: 2pp4A
Description: No description for 2pp4A was found.

Predicted Domain #4
Region A:
Residues: [316-441]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HGVASAEFGD IFIQLEAPTS NGSSAVFKRR SSDSMMEHGG HNGLQEWNEY MASGGAGYPP  60
   61 PPSKRLTLHP AHSVVAYGEY GVSSAEGLPS AAAFMQRDER DLRMSEAQAR HAAPPQRAGN 120
  121 PQPNPN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [442-577]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAAPGAPGAG GEEEWKNIHT MLNCISAMVD KTKRAITILQ QRGIEPQHPN SGQEVTPAAM  60
   61 AELRRQTEEK VAEFKRNAED AVTQVKRQAV IEIQRAVVAA ETRAAEIMTQ ERLRMEKFFM 120
  121 EMSRHSSGER DLDNKS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.522879
Match: 1wq6A
Description: The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for AML1-ETO'S activity
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [578-674]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSMASAQNGS NLQQQCWNCG RKATETCSGC NMARYCSASC QYRDWDSHHQ VCGNTRASEL  60
   61 SAKHLHSASN LSLRNAMATR SPPTPNSAAH LQAAAAA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.69897
Match: 2oddA
Description: No description for 2oddA was found.

Predicted Domain #7
Region A:
Residues: [675-743]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAAAAGAREA VSAPVGGPGA GIAVGTGAGS GGQSGGGGGG GGGGGGGAAA AAVAAATPGA  60
   61 LVANGLGSK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle