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Protein Overview: king-tubby-PB

General Information:
Name(s) found: king-tubby-PB / FBpp0088961 [FlyBase]
Description(s) found:
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  • gi|45552773|ref|NP_995911.1| king tubby, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|45445339|gb|AAS64753.1| king tubby, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|27819815|gb|AAO24956.1| RE38560p [Drosophila melanogaster] [NCBI NR]
  • Protein king tubby OS=Drosophila melanogaster GN=ktub PE=1 SV=1 [Swiss-Prot]
  • The gene king tubby is referred to in FlyBase by the symbol Dmel\king-tubby (CG9398, FBgn0015721). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:16989435..17011220. It has the cytological map location 57B20-57C2. Its molecular function is unknown. It is reported to be involved in the biological process</span>: sensory perception of smell. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • (AAS64753) CG9398-PB [DrosMelano7227.FASTAC.txt]
  • CG9398-PB, isoform B [Drosophila melanogaster]gi|27819815|gb|AAO24956.1| RE38560p [Drosophila melanogaster]gi|45552773|ref|NP_995911.1| CG9398-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(16990081..16990122,17009135..17009408,17009506..17009973,17010031..17010221,17010279..17010416,17010475..17010744); ID=FBpp0088961; name=king-tubby-PB; parent=FBgn0015721,FBtr0089600; dbxref=FlyBase:FBpp0088961,FlyBase_Annotation [fly-100309-contam.fasta]
  • king tubby CG9398-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG9398-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • RE38560p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(16990081..16990122,17009135..17009408,17009506..17009973,17010031..17010221,17010279..17010416,17010475..17010744); ID=FBpp0088961; name=king-tubby-PB; parent=FBgn0015721,FBtr0089600; dbxref=FlyBase:FBpp0088961,FlyBase_Annotation_IDs:CG9398-PB,GB_protein:AAS64753.1,REFSEQ:NP_995911,GB_protein:AAS64753; MD5=49278e27cc34ae681e7744cf79b38999; length=460; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(16990081..16990122,17009135..17009408,17009506..17009973,17010031..17010221,17010279..17010416,17010475..17010744); ID=FBpp0088961; name=king-tubby-PB; parent=FBgn0015721,FBtr0089600; dbxref=FlyBase:FBpp0088961,FlyBase_Annotation_IDs:CG9398-PB,GB_protein:AAS64753.1,REFSEQ:NP_995911,GB_protein:AAS64753; MD5=49278e27cc34ae681e7744cf79b38999; length=460; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Protein king tubby OS=Drosophila melanogaster GN=king-tubby PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:join(16990081..16990122,17009135..17009408,17009506..17009973,17010031..17010221,17010279..17010416,17010475..17010744); ID=FBpp0088961; name=king-tubby-PB; parent=FBgn0015721,FBtr0089600; dbxref=FlyBase:FBpp0088961,FlyBase_Annotation_IDs:CG9398-PB,GB_protein:AAS64753.1,REFSEQ:NP_995911,GB_protein:AAS64753,FlyMine:FBpp0088961,modMine:FBpp0088961; MD5=49278e27cc34ae681e7744cf79b38999; length=460; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:join(21102576..21102617,21121630..21121903,21122001..21122468,21122526..21122716,21122774..21122911,21122970..21123239); ID=FBpp0088961; name=ktub-PB; parent=FBgn0015721,FBtr0089600; dbxref=FlyBase:FBpp0088961,FlyBase_Annotation_IDs:CG9398-PB,GB_protein:AAS64753.1,REFSEQ:NP_995911,GB_protein:AAS64753,FlyMine:FBpp0088961,modMine:FBpp0088961; MD5=49278e27cc34ae681e7744cf79b38999; length=460; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(21102576..21102617,21121630..21121903,21122001..21122468,21122526..21122716,21122774..21122911,21122970..21123239); ID=FBpp0088961; name=ktub-PB; parent=FBgn0015721,FBtr0089600; dbxref=FlyBase:FBpp0088961,FlyBase_Annotation_IDs:CG9398-PB,GB_protein:AAS64753.1,REFSEQ:NP_995911,GB_protein:AAS64753,FlyMine:FBpp0088961,modMine:FBpp0088961; MD5=49278e27cc34ae681e7744cf79b38999; length=460; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0088961 type=protein; loc=2R:join(21102576..21102617,21121630..21121903,21122001..21122468,21122526..21122716,21122774..21122911,21122970..21123239); ID=FBpp0088961; name=ktub-PB; parent=FBgn0015721,FBtr0089600; dbxref=FlyBase:FBpp0088961,FlyBase_Annotation_IDs:CG9398-PB,GB_protein:AAS64753.1,REFSEQ:NP_995911,GB_protein:AAS64753,FlyMine:FBpp0088961,modMine:FBpp0088961; MD5=49278e27cc34ae681e7744cf79b38999; length=460; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(21102576..21102617,21121630..21121903,21122001..21122468,21122526..21122716,21122774..21122911,21122970..21123239); ID=FBpp0088961; name=ktub-PB; parent=FBgn0015721,FBtr0089600; dbxref=FlyBase:FBpp0088961,FlyBase_Annotation_IDs:CG9398-PB,GB_protein:AAS64753.1,REFSEQ:NP_995911,GB_protein:AAS64753,UniProt/Swiss-Prot:Q86PC9,FlyMine:FBpp0088961,modMine:FBpp0088961; MD5=49278e27cc34ae681e7744cf79b38999; length=460; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 460 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IDA]
    Biological Process: sensory perception of smell [NAS]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGINSRNQK MEQQRQLMEA YIRQKRASPG MVQASDLQIN RPMSGMRSNS RELHAYDGPM  60
   61 QFISSPQNPD QILTNGSPGG INPVAMNTSR NHSNNMRSLS TINQEADLIE EISSHELEDE 120
  121 ESSPVTVIEQ HQQSASHSAN STQSQKPRAR QHSFSDNLDE DDYTNRNVAG AAPVRPAGMA 180
  181 SSPYKDATLD GSSNGTGNGT GGESEGDVIG NIDQFVMQPA PQGVLYKCRI TRDRKGMDRG 240
  241 LFPIYYLHLE RDYGKKIFLL GGRKRKKSKT SNYIVSCDPT DLSRNADGFC GKLRSNVFGT 300
  301 SFTVFDNGNK ESTESPRLDL AVIIYDTNIL GFKGPRNMTV ILPGMTEDDQ RVKISSADPK 360
  361 QQGILDLWKM KNMDNIVELH NKTPVWNDET QSYVLNFHGR VTQASVKNFQ LVHDSDPEYI 420
  421 VMQFGRTSED VFTMDYRYPL CAMQAFAIAL SSFDGKIACE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..205] MSA 9.084997 View MSA. No confident structure predictions are available.
    2 View Details [206..460] PSI-BLAST 124.0 Transcriptional factor tubby, C-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • G-protein coupled photoreceptor activity
    		•  1.54113214160576 bayes_pls_golite062009
  • photoreceptor activity
    		•  1.38683715974935 bayes_pls_golite062009
  • binding
    		•  1.343797485538 bayes_pls_golite062009
  • protein binding
    		•  0.380701847368155 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  0.08438243032211 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle