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Protein Overview: sdt-PD, FBpp0300539

General Information:
Name(s) found: FBpp0300539 [FlyBase]
sdt-PD / FBpp0088913 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • type=protein; loc=X:join(8126526..8126939,8129622..8129853,8129915..8131202,8131265..8131461,8131843..8131974,8132040..8132221,8132285..8132479); ID=FBpp0300539; name=sdt-PK; parent=FBgn0261873,FBtr0308219; dbxref=FlyBase:FBpp0300539,FlyBase_Annotation_IDs:CG32717-PK,REFSEQ:NP_001245575,GB_protein:AFH07289; MD5=4231f95ba9f60351628c64729e569cf4; length=879; release=r5.56; species=Dmel; [FlyBase]
  • The gene stardust is referred to in FlyBase by the symbol Dmel\sdt (CG32717, FBgn0243505). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8072582..8133487. It has the cytological map location 7D17-7D22. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: establishment or maintenance of neuroblast polarity; zonula adherens assembly; establishment or maintenance of polarity of embryonic epithelium; establishment or maintenance of epithelial cell apical/basal polarity. 53 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; salivary gland; zonula adherens; amnioserosa; embryonic epidermis; photoreceptor cell stalk; trachea; spot adherens junction; macrophage; embryo. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 879 amino acids

    Gene Ontology:
    Cellular Component: apicolateral plasma membrane [IDA]
    adherens junction [IDA]
    subapical complex [TAS]
    cell-cell adherens junction [NAS]
    cytoplasm [NAS]
    membrane [ISS][NAS]
    septate junction [TAS]
    apical cortex [IDA]
    plasma membrane [ISS]
    apical plasma membrane [IDA][NAS][TAS]
    Biological Process: [NOT]establishment or maintenance of neuroblast polarity [IEP][IMP]
    cell-cell junction assembly [NAS]
    morphogenesis of an epithelium [NAS][TAS]
    zonula adherens assembly [IMP][TAS]
    establishment or maintenance of epithelial cell apical/basal polarity [IEP][IMP][IPI][TAS]
    establishment or maintenance of cell polarity [NAS]
    morphogenesis of a polarized epithelium [TAS]
    establishment or maintenance of polarity of embryonic epithelium [IMP]
    Molecular Function: protein binding [IPI][ISS][TAS]
    guanylate kinase activity [ISS][NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVSTLHITL ENNGNVAAGQ PAAVAAASVV GAATSPTKFA VLSAQQLQLQ LQQQQQQQNE  60
   61 KENHMNNNNN NSDYCDMNGN GVGMGNGGSG GPGSLTPQSP DQYVGSPVSS AATPQRTASA 120
  121 LRRGIQIQRS STRLRQQQEQ LRRRREEEER IAQQNEFLRN SLRGSRKLKA LQDTATPGKA 180
  181 VAQQQQQATL ATQVVGVENE AYLPDEDQPQ AEQIDGYGEL IAALTRLQNQ LSKSGLSTLA 240
  241 GRVSAAHSVL ASASVAHVLA ARTAVLQRRR SRVSGPLHHS SLGLQKDIVE LLTQSNTAAA 300
  301 IELGNLLTSH EMEGLLLAHD RIANHTDGTP SPTPTPTPAI GAATGSTLSS PVAGPKRNLG 360
  361 MVVPPPVVPP PLAQRGAMPL PRGESPPPVP MPPLATMPMS MPVNLPMSAC FGTLNDQNDN 420
  421 IRIIQIEKST EPLGATVRNE GEAVVIGRIV RGGAAEKSGL LHEGDEILEV NGQELRGKTV 480
  481 NEVCALLGAM QGTLTFLIVP AGSPPSVGVM GGTTGSQLAG LGGAHRDTAV LHVRAHFDYD 540
  541 PEDDLYIPCR ELGISFQKGD VLHVISREDP NWWQAYREGE EDQTLAGLIP SQSFQHQRET 600
  601 MKLAIAEEAG LARSRGKDGS GSKGATLLCA RKGRKKKKKA SSEAGYPLYA TTAPDETDPE 660
  661 EILTYEEVAL YYPRATHKRP IVLIGPPNIG RHELRQRLMA DSERFSAAVP HTSRARREGE 720
  721 VPGVDYHFIT RQAFEADILA RRFVEHGEYE KAYYGTSLEA IRTVVASGKI CVLNLHPQSL 780
  781 KLLRASDLKP YVVLVAPPSL DKLRQKKLRN GEPFKEEELK DIIATARDME ARWGHLFDMI 840
  841 IINNDTERAY HQLLAEINSL EREPQWVPAQ WVHNNRDES

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..108] deduced N/A No confident structure predictions are available.
    2 View Details [109..270] deduced N/A No confident structure predictions are available.
    3 View Details [271..361] FFAS03 1.28 NMR structure of L27 heterodimer from C. elegans Lin-7 and H. sapiens Lin-2 scaffold proteins
    4 View Details [362..514] PSI-BLAST 15.045757 Solution structure of the PDZ domain of Pals1 protein
    5 View Details [515..879] PSI-BLAST 51.0 Psd-95; Guanylate kinase-like domain of Psd-95

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  3.2595117613307 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  3.03529700765506 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.83180079733297 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.39826531242265 bayes_pls_golite062009
  • protein binding
    		•  2.35875654816667 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  1.79696347300128 bayes_pls_golite062009
  • guanylate kinase activity
    		•  1.70730560221787 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  1.69528181005421 bayes_pls_golite062009
  • signal transducer activity
    		•  1.51162321843898 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.51162321843898 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.00130123171287 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.64214865642772 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.387065538161985 bayes_pls_golite062009
  • receptor binding
    		•  0.359972518335054 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.54

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle