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Protein Overview: sdt-PE

General Information:
Name(s) found: sdt-PE / FBpp0088912 [FlyBase]
Description(s) found:
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  • gi|45554489|ref|NP_996376.1| stardust, isoform E [Drosophila melanogaster] [NCBI NR]
  • gi|45446855|gb|AAS65284.1| stardust, isoform E [Drosophila melanogaster] [NCBI NR]
  • The gene stardust is referred to in FlyBase by the symbol Dmel\sdt (CG32717, FBgn0243505). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8072582..8133487. It has the cytological map location 7D17-7D22. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: establishment or maintenance of neuroblast polarity; zonula adherens assembly; establishment or maintenance of polarity of embryonic epithelium; establishment or maintenance of epithelial cell apical/basal polarity. 53 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; salivary gland; zonula adherens; amnioserosa; embryonic epidermis; photoreceptor cell stalk; trachea; spot adherens junction; macrophage; embryo. It has 7 annotated transcripts and 7 annotated polypeptides. [FlyBase]
  • (AAS65284) CG32717-PE [DrosMelano7227.FASTAC.txt]
  • CG32717-PE, isoform E [Drosophila melanogaster]gi|45554489|ref|NP_996376.1| CG32717-PE [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=X:join(8111088..8111107,8117661..8117899,8117989..8118080,8118818..8120116,8121904..8122131,8129622..8129853,8129915..8131202,8131265..8131461,8131843..8131974,8132040..8132221,8132285..8132479); ID=FBpp0088912; name=sdt-PE; parent=FBgn0 [fly-100309-contam.fasta]
  • stardust CG32717-PE, isoform E [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG32717-PE, isoform E [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=X:join(8111088..8111107,8117661..8117899,8117989..8118080,8118818..8120116,8121904..8122131,8129622..8129853,8129915..8131202,8131265..8131461,8131843..8131974,8132040..8132221,8132285..8132479); ID=FBpp0088912; name=sdt-PE; parent=FBgn0243505,FBtr0089974; dbxref=FlyBase_Annotation_IDs:CG32717-PE,GB_protein:AAS65284.1,FlyBase:FBpp0088912,REFSEQ:NP_996376,GB_protein:AAS65284; MD5=55273d526072a93d267a0ec37196b09d; length=1367; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=X:join(8111088..8111107,8117661..8117899,8117989..8118080,8118818..8120116,8121904..8122131,8129622..8129853,8129915..8131202,8131265..8131461,8131843..8131974,8132040..8132221,8132285..8132479); ID=FBpp0088912; name=sdt-PE; parent=FBgn0243505,FBtr0089974; dbxref=FlyBase_Annotation_IDs:CG32717-PE,GB_protein:AAS65284.1,FlyBase:FBpp0088912,REFSEQ:NP_996376,GB_protein:AAS65284; MD5=55273d526072a93d267a0ec37196b09d; length=1367; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Stardust, isoform E OS=Drosophila melanogaster GN=sdt PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=X:join(8111088..8111107,8117661..8117899,8117989..8118080,8118818..8120116,8121904..8122131,8129622..8129853,8129915..8131202,8131265..8131461,8131843..8131974,8132040..8132221,8132285..8132479); ID=FBpp0088912; name=sdt-PE; parent=FBgn0261873,FBtr0089974; dbxref=FlyBase_Annotation_IDs:CG32717-PE,GB_protein:AAS65284.1,FlyBase:FBpp0088912,REFSEQ:NP_996376,GB_protein:AAS65284,FlyMine:FBpp0088912,modMine:FBpp0088912; MD5=55273d526072a93d267a0ec37196b09d; length=1367; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=X:join(8217055..8217074,8223628..8223866,8223956..8224047,8224785..8226083,8227871..8228098,8235589..8235820,8235882..8237169,8237232..8237428,8237810..8237941,8238007..8238188,8238252..8238446); ID=FBpp0088912; name=sdt-PE; parent=FBgn0261873,FBtr0089974; dbxref=FlyBase_Annotation_IDs:CG32717-PE,GB_protein:AAS65284.1,FlyBase:FBpp0088912,REFSEQ:NP_996376,GB_protein:AAS65284,FlyMine:FBpp0088912,modMine:FBpp0088912; MD5=55273d526072a93d267a0ec37196b09d; length=1367; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=X:join(8217055..8217074,8223628..8223866,8223956..8224047,8224785..8226083,8227871..8228098,8235589..8235820,8235882..8237169,8237232..8237428,8237810..8237941,8238007..8238188,8238252..8238446); ID=FBpp0088912; name=sdt-PE; parent=FBgn0261873,FBtr0089974; dbxref=FlyBase_Annotation_IDs:CG32717-PE,GB_protein:AAS65284.1,FlyBase:FBpp0088912,REFSEQ:NP_996376,GB_protein:AAS65284,FlyMine:FBpp0088912,modMine:FBpp0088912; MD5=55273d526072a93d267a0ec37196b09d; length=1367; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of E2QD98, Stardust, isoform E OS=Drosophila melanogaster GN=sdt PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0088912 type=protein; loc=X:join(8217055..8217074,8223628..8223866,8223956..8224047,8224785..8226083,8227871..8228098,8235589..8235820,8235882..8237169,8237232..8237428,8237810..8237941,8238007..8238188,8238252..8238446); ID=FBpp0088912; name=sdt-PE; parent=FBgn0261873,FBtr0089974; dbxref=FlyBase_Annotation_IDs:CG32717-PE,GB_protein:AAS65284.1,FlyBase:FBpp0088912,REFSEQ:NP_996376,GB_protein:AAS65284,FlyMine:FBpp0088912,modMine:FBpp0088912; MD5=55273d526072a93d267a0ec37196b09d; length=1367; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=X:join(8217055..8217074,8223628..8223866,8223956..8224047,8224785..8226083,8227871..8228098,8235589..8235820,8235882..8237169,8237232..8237428,8237810..8237941,8238007..8238188,8238252..8238446); ID=FBpp0088912; name=sdt-PE; parent=FBgn0261873,FBtr0089974; dbxref=FlyBase_Annotation_IDs:CG32717-PE,GB_protein:AAS65284.1,FlyBase:FBpp0088912,REFSEQ:NP_996376,GB_protein:AAS65284,UniProt/TrEMBL:Q7KVT3,FlyMine:FBpp0088912,modMine:FBpp0088912; MD5=55273d526072a93d267a0ec37196b09d; length=1367; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1367 amino acids

    Gene Ontology:
    Cellular Component: apicolateral plasma membrane [IDA]
    adherens junction [IDA]
    subapical complex [TAS]
    cell-cell adherens junction [NAS]
    cytoplasm [NAS]
    membrane [ISS][NAS]
    septate junction [TAS]
    apical cortex [IDA]
    plasma membrane [ISS]
    apical plasma membrane [IDA][NAS][TAS]
    Biological Process: [NOT]establishment or maintenance of neuroblast polarity [IEP][IMP]
    cell-cell junction assembly [NAS]
    morphogenesis of an epithelium [NAS][TAS]
    zonula adherens assembly [IMP][TAS]
    establishment or maintenance of epithelial cell apical/basal polarity [IEP][IMP][IPI][TAS]
    establishment or maintenance of cell polarity [NAS]
    morphogenesis of a polarized epithelium [TAS]
    establishment or maintenance of polarity of embryonic epithelium [IMP]
    Molecular Function: protein binding [IPI][ISS][TAS]
    guanylate kinase activity [ISS][NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRILKQWNRR RSGSSIVVLD GDDLKPCLPD DYISGQHHLN HQQQLQLQQQ LQQQHPLQQQ  60
   61 HYRTHSGDIR EIDQEMLTML SVNQDNGPHR EMAVDCPDTF IARNKTPPRY PPPRPPQKHK 120
  121 KSTNTTTTTT ITALTNNDHA NKMLIVAYHS SHQHEQLQQQ HPSKTSTTTT TIALDVATQN 180
  181 LYNQKQQNKL EQIENYENCL QSERNEQHEQ QFEQQKQHQA TTAMAATQVA QQQTPSHKLQ 240
  241 ATLSSDPNGN SNSNNNSHIV GISSSSSSNN SSITDDFLCV VDGLYQGRKD TASPSSSAFD 300
  301 EVMSKHTLDS FGSIAYRHLH QQHQATSNGN SSSNTSNTNS NTNSNTNSNS NTNGNTSNNT 360
  361 AVSTKTATVT KTGVSSSNSN SNSLNSSNSS MHTSSSSSGH SSNIASATSS SSATSSSTVP 420
  421 DDLSLAPPGY EVSQQQQQQH LVATPVTMLL PPMAKHRELP VDVPDSFIEM VKTTPRYPPP 480
  481 AHLSSRGSLL SNGSASTAHT TLSSMGVAPS PVTATAAAAA SASAACATTA VAAAAVSGVA 540
  541 DGDARRVADE LNGNAKPVPP PRDHLRVEKD GRLVNCSPAP QLPDRRAPGN ASSGSSGATT 600
  601 HPLQHQQIAQ IVEPTLEQLD SIKKYQEQLR RRREEEERIA QQNEFLRNSL RGSRKLKALQ 660
  661 DTATPGKAVA QQQQQATLAT QVVGVENEAY LPDEDQPQAE QIDGYGELIA ALTRLQNQLS 720
  721 KSGLSTLAGR VSAAHSVLAS ASVAHVLAAR TAVLQRRRSR VSGPLHHSSL GLQKDIVELL 780
  781 TQSNTAAAIE LGNLLTSHEM EGLLLAHDRI ANHTDGTPSP TPTPTPAIGA ATGSTLSSPV 840
  841 AGPKRNLGMV VPPPVVPPPL AQRGAMPLPR GESPPPVPMP PLATMPMSMP VNLPMSACFG 900
  901 TLNDQNDNIR IIQIEKSTEP LGATVRNEGE AVVIGRIVRG GAAEKSGLLH EGDEILEVNG 960
  961 QELRGKTVNE VCALLGAMQG TLTFLIVPAG SPPSVGVMGG TTGSQLAGLG GAHRDTAVLH1020
 1021 VRAHFDYDPE DDLYIPCREL GISFQKGDVL HVISREDPNW WQAYREGEED QTLAGLIPSQ1080
 1081 SFQHQRETMK LAIAEEAGLA RSRGKDGSGS KGATLLCARK GRKKKKKASS EAGYPLYATT1140
 1141 APDETDPEEI LTYEEVALYY PRATHKRPIV LIGPPNIGRH ELRQRLMADS ERFSAAVPHT1200
 1201 SRARREGEVP GVDYHFITRQ AFEADILARR FVEHGEYEKA YYGTSLEAIR TVVASGKICV1260
 1261 LNLHPQSLKL LRASDLKPYV VLVAPPSLDK LRQKKLRNGE PFKEEELKDI IATARDMEAR1320
 1321 WGHLFDMIII NNDTERAYHQ LLAEINSLER EPQWVPAQWV HNNRDES

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..83] deduced N/A No confident structure predictions are available.
    2 View Details [84..183] MSA 2.193997 View MSA. No confident structure predictions are available.
    3 View Details [184..409] MSA 2.197996 View MSA. No confident structure predictions are available.
    4 View Details [410..699] deduced N/A No confident structure predictions are available.
    5 View Details [700..771] FFAS03 0.965 2.1 Angstrom crystal structure of the PALS-1-L27N and PATJ L27 heterodimer complex
    6 View Details [772..886] PSI-BLAST 6.39794 NMR structure of L27 heterodimer from C. elegans Lin-7 and H. sapiens Lin-2 scaffold proteins
    7 View Details [887..1003] PSI-BLAST 20.30103 Solution structure of the PDZ domain of Pals1 protein
    8 View Details [1004..1367] PSI-BLAST 93.0 Psd-95; Guanylate kinase-like domain of Psd-95

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  3.03622697799261 bayes_pls_golite062009
  • binding
    		•  2.36911654864963 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  1.74246069832658 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  1.69175028046159 bayes_pls_golite062009
  • guanylate kinase activity
    		•  1.52039939090373 bayes_pls_golite062009
  • protein binding
    		•  1.08813585723961 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.450006870427269 bayes_pls_golite062009
  • catalytic activity
    		•  0.315768210630189 bayes_pls_golite062009
    6 No functions predicted.
    7
    Term Confidence Notes
  • binding
    		•  3.2595117613307 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  3.03529700765506 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.83180079733297 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.39826531242265 bayes_pls_golite062009
  • protein binding
    		•  2.35875654816667 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  1.79696347300128 bayes_pls_golite062009
  • guanylate kinase activity
    		•  1.70730560221787 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  1.69528181005421 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.68920668586004 bayes_pls_golite062009
  • signal transducer activity
    		•  1.51162321843898 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.51162321843898 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.64214865642772 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.387065538161985 bayes_pls_golite062009
  • receptor binding
    		•  0.359972518335054 bayes_pls_golite062009
  • actin binding
    		•  0.13059495339034 bayes_pls_golite062009
    8 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle