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Protein Overview: APC7-PA

General Information:
Name(s) found: APC7-PA / FBpp0070907 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • The gene Anaphase Promoting Complex 7 is referred to in FlyBase by the symbol Dmel\APC7 (CG14444, FBgn0029879). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:6491078..6493733. It has the cytological map location 6C1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. There is experimental evidence that it is involved in the biological process</span>: mitosis. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 615 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: mitosis [IMP]
    Molecular Function: binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASFLIVVEK MEIALFANAK KLYDHKLYEC VIPAADLLRT VLKNDRYVAT LDVEYQVLLY  60
   61 LLNANYKERN YRAALRHFDE IIHKRRLMMR HKNAVLVAIE SSYPEFGDAE QRRRAAECYR 120
  121 QIGNTDMAIE TLLQVPPTLR SPRINLMLAR LQHHGSRHGT TKKSEAVLAY KEVIRECPMA 180
  181 LQVIEALLEL GVNGNEINSL VMHAATVPDH FDWLSKWIKA LAQMFNFKHS DASQTFLMLH 240
  241 DNTTLRCNEH LMMALGKCLY YNGDYFQAED IFSSTLCANP DNVEAIGLMA VLCGQEGGCE 300
  301 QDSADMDYLF AKVSSEVKYT ASHWFAHAQL LYDEGKFERG LNFVEKCLDS EPRNHEALIL 360
  361 RGRLLIALER HTQAVCAFRT AQMVAPYRFE IYRGLFHSYL AQKRFKEANA LCNWTIRLFQ 420
  421 NSPRSFTMFG RTLFLFPDPR MRRTARKFAE KSLKINHIYT PAVNLIADIC QVEGPTKAII 480
  481 KLLEKHVIIF PKVNLLNHLG DIMRKQKEPV KAMEYYYKAL RQDPKSKRTL RGLRLLAKSD 540
  541 DESPVLDESD DIGMDNQQSI NDLTTLCEAT NAQGAEGAES VENSREASSS AAARSGQEED 600
  601 VDEHDWIDVP DGMSY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..139] PSI-BLAST 6.69897 Helicobacter cysteine rich protein C (HcpC)
    2 View Details [140..538] PSI-BLAST 58.522879 The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
    3 View Details [539..615] PSI-BLAST 21.522879 No description for 2j9qA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.52126334054344 bayes_pls_golite062009
  • protein binding
    		•  1.52807685989528 bayes_pls_golite062009
  • enzyme binding
    		•  0.44905827271946 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.41706917101675 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.322371143360832 bayes_pls_golite062009
  • hydrolase activity
    		•  0.252678932946087 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.244038930707726 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.215617899962405 bayes_pls_golite062009
  • DNA binding
    		•  0.17736976899009 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle