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Protein Overview: gi|54673670, gi|...

General Information:
Name(s) found: gi|54673670 [NCBI NR]
gi|40068475 [NCBI NR]
gi|119578273 [NCBI NR]
Description(s) found:
Found 23 descriptions.
SHOW ALL
  • gi|54673670|gb|AAH43148.2| Twinfilin, actin-binding protein, homolog 1 (Drosophila) [Homo sapiens] [NCBI NR]
  • gi|40068475|ref|NP_002813.2| twinfilin 1 [Homo sapiens] [NCBI NR]
  • gi|119578273|gb|EAW57869.1| PTK9 protein tyrosine kinase 9, isoform CRA_b [Homo sapiens] [NCBI NR]
    • Organism: Homo sapiens
    Length: 384 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTRRGRRRSS HFLGPPAGAA GCTQRRSREL AAAAMSHQTG IQASEDVKEI FARARNGKYR  60
   61 LLKISIENEQ LVIGSYSQPS DSWDKDYDSF VLPLLEDKQP CYILFRLDSQ NAQGYEWIFI 120
  121 AWSPDHSHVR QKMLYAATRA TLKKEFGGGH IKDEVFGTVK EDVSLHGYKK YLLSQSSPAP 180
  181 LTAAEEELRQ IKINEVQTDV GVDTKHQTLQ GVAFPISREA FQALEKLNNR QLNYVQLEID 240
  241 IKNEIIILAN TTNTELKDLP KRIPKDSARY HFFLYKHSHE GDYLESIVFI YSMPGYTCSI 300
  301 RERMLYSSCK SRLLEIVERQ LQMDVIRKIE IDNGDELTAD FLYEEVHPKQ HAHKQSFAKP 360
  361 KGPAGKRGIR RLIRGPAETE ATTD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..199] PSI-BLAST 47.0 Adf-H domain of twinfilin isoform-1
    2 View Details [200..384] PSI-BLAST 41.30103 No description for 2d8bA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  7.52071741004022 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  6.04859625643932 bayes_pls_golite062009
  • actin filament binding
    		•  5.45532510538573 bayes_pls_golite062009
  • binding
    		•  2.41877859618486 bayes_pls_golite062009
  • protein kinase activity
    		•  2.22634235673758 bayes_pls_golite062009
  • protein binding
    		•  1.87981807141519 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  1.87091423399482 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.67227267699496 bayes_pls_golite062009
  • kinase activity
    		•  1.55883505515498 bayes_pls_golite062009
  • phosphatidylinositol-4,5-bisphosphate binding
    		•  1.3406661967545 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.30213296029859 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.14209355225632 bayes_pls_golite062009
  • signal transducer activity
    		•  1.14209355225632 bayes_pls_golite062009
  • transferase activity
    		•  0.591259446255369 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.482954032096802 bayes_pls_golite062009
  • structural molecule activity
    		•  0.391701411061931 bayes_pls_golite062009
  • actin monomer binding
    		•  0.224304003054399 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle