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Protein Overview: OGT

General Information:
Name(s) found: OGT [HGNC (HUGO)]
Description(s) found:
Found 31 descriptions.
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  • O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 1046 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSVGNVAD STEPTKRMLS FQGLAELAHR EYQAGDFEAA ERHCMQLWRQ EPDNTGVLLL  60
   61 LSSIHFQCRR LDRSAHFSTL AIKQNPLLAE AYSNLGNVYK ERGQLQEAIE HYRHALRLKP 120
  121 DFIDGYINLA AALVAAGDME GAVQAYVSAL QYNPDLYCVR SDLGNLLKAL GRLEEAKACY 180
  181 LKAIETQPNF AVAWSNLGCV FNAQGEIWLA IHHFEKAVTL DPNFLDAYIN LGNVLKEARI 240
  241 FDRAVAAYLR ALSLSPNHAV VHGNLACVYY EQGLIDLAID TYRRAIELQP HFPDAYCNLA 300
  301 NALKEKGSVA EAEDCYNTAL RLCPTHADSL NNLANIKREQ GNIEEAVRLY RKALEVFPEF 360
  361 AAAHSNLASV LQQQGKLQEA LMHYKEAIRI SPTFADAYSN MGNTLKEMQD VQGALQCYTR 420
  421 AIQINPAFAD AHSNLASIHK DSGNIPEAIA SYRTALKLKP DFPDAYCNLA HCLQIVCDWT 480
  481 DYDERMKKLV SIVADQLEKN RLPSVHPHHS MLYPLSHGFR KAIAERHGNL CLDKINVLHK 540
  541 PPYEHPKDLK LSDGRLRVGY VSSDFGNHPT SHLMQSIPGM HNPDKFEVFC YALSPDDGTN 600
  601 FRVKVMAEAN HFIDLSQIPC NGKAADRIHQ DGIHILVNMN GYTKGARNEL FALRPAPIQA 660
  661 MWLGYPGTSG ALFMDYIITD QETSPAEVAE QYSEKLAYMP HTFFIGDHAN MFPHLKKKAV 720
  721 IDFKSNGHIY DNRIVLNGID LKAFLDSLPD VKIVKMKCPD GGDNADSSNT ALNMPVIPMN 780
  781 TIAEAVIEMI NRGQIQITIN GFSISNGLAT TQINNKAATG EEVPRTIIVT TRSQYGLPED 840
  841 AIVYCNFNQL YKIDPSTLQM WANILKRVPN SVLWLLRFPA VGEPNIQQYA QNMGLPQNRI 900
  901 IFSPVAPKEE HVRRGQLADV CLDTPLCNGH TTGMDVLWAG TPMVTMPGET LASRVAASQL 960
  961 TCLGCLELIA KNRQEYEDIA VKLGTDLEYL KKVRGKVWKQ RISSPLFNTK QYTMELERLY1020
 1021 LQMWEHYAAG NKPDHMIKPV EVTESA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MIS12 No Comments Cheeseman, I.M., et al. (2004)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..425] PSI-BLAST 78.0 The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
    2 View Details [426..550] PSI-BLAST 30.0 No description for 2q7fA was found.
    3 View Details [551..644] deduced N/A No confident structure predictions are available.
    4 View Details [645..702] deduced N/A No confident structure predictions are available.
    5 View Details [703..803] deduced N/A No confident structure predictions are available.
    6 View Details [804..1046] PSI-BLAST 4.69897 No description for 2gejA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.71974493738804 bayes_pls_golite062009
  • phosphoprotein phosphatase activity
    		•  2.48921024987872 bayes_pls_golite062009
  • phosphatase activity
    		•  2.4502869290841 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  2.38923256228405 bayes_pls_golite062009
  • hydrolase activity
    		•  2.16486484513356 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.07186557005331 bayes_pls_golite062009
  • protein binding
    		•  1.6279032205159 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  0.949260584741775 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.897652181945102 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.89107071408431 bayes_pls_golite062009
  • acetylglucosaminyltransferase activity
    		•  0.78476205818302 bayes_pls_golite062009
  • signal sequence binding
    		•  0.71760275307167 bayes_pls_golite062009
  • DNA binding
    		•  0.69174990631975 bayes_pls_golite062009
  • transferase activity
    		•  0.127854220687373 bayes_pls_golite062009
  • transcription factor activity
    		•  0.0355464132591463 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle