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Protein Overview: PITPNB

General Information:
Name(s) found: PITPNB [HGNC (HUGO)]
Description(s) found:
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  • gi|6912594|ref|NP_036531.1| phosphatidylinositol transfer protein, beta [Homo sapiens] [NCBI NR]
  • gi|6572213|emb|CAB63033.1| phosphatidylinositol transfer protein, beta [Homo sapiens] [NCBI NR]
  • gi|47678613|emb|CAG30427.1| PITPNB [Homo sapiens] [NCBI NR]
  • gi|17511691|gb|AAH18704.1| Phosphatidylinositol transfer protein, beta [Homo sapiens] [NCBI NR]
  • gi|1346772|sp|P48739.2|PIPNB_HUMAN RecName: Full=Phosphatidylinositol transfer protein beta isoform; Short=PtdIns transfer protein beta; Short=PtdInsTP; Short=PI-TP-beta [NCBI NR]
  • gi|1060905|dbj|BAA06277.1| phosphatidylinositol transfer protein [Homo sapiens] [NCBI NR]
  • phosphatidylinositol transfer protein, beta [HGNC (HUGO)]
  • Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens GN=PITPNB PE=1 SV=2 [Swiss-Prot]
  • phosphotidylinositol transfer protein, beta [HMR_022704.fasta]
  • PREDICTED: phosphatidylinositol transfer protein, beta [Pan troglodytes]gi|6912594|ref|NP_036531.1| phosphatidylinositol transfer protein, beta [Homo sapiens]gi|17511691|gb|AAH18704.1| Phosphatidylinositol transfer protein, beta [Homo sapiens]gi|657221 [nrdb_11152004_Chlamydomonas]
  • Phosphatidylinositol transfer protein beta isoform (PtdIns transfer protein beta) (PtdInsTP) (PI-TP-beta) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 phosphatidylinositol transfer protein, beta [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • (NM_012399) phosphotidylinositol transfer protein, beta [Homo sapiens] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • phosphatidylinositol transfer protein, beta [Homo sapiens] [NCBI-RefSeq_Human_na_12_06_2006_con_reversed.fasta]
  • Tax_Id=9606 PhosPhatidylinositol transfer Protein, beta [EBI-IPI_human_3.12_11-03-2005_con_reversed.fasta]
  • Tax_Id=9606 PhosPhatidylinositol transfer Protein, beta [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • phosphotidylinositol transfer protein, beta [Homo sapiens] [HumanGallus06162005.fasta]
  • PITPNB [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • phosphatidylinositol transfer protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Phosphatidylinositol transfer protein, beta [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN, BETA [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • RecName: Full=Phosphatidylinositol transfer protein beta isoform; Short=PtdIns transfer protein beta; Short=PtdInsTP; Short=PI-TP-beta [NCBI-RefSeq_human_na_10-15-2008_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=PITPNB Isoform 1 of Phosphatidylinositol transfer protein beta isoform [human-ipi-250309-contam.fasta]
  • OTTHUMP00000028575 [Homo sapiens] [nr-271106-contam.fasta]
  • IPI:IPI00334907.3|SWISS-PROT:P48739-1|TREMBL:B2R7P6|ENSEMBL:ENSP00000334738|REFSEQ:NP_036531|H-INV:HIT000038406|VEGA:OTTHUMP00000028575;OTTHUMP00000198846 Tax_Id=9606 Gene_Symbol=PITPNB Isoform 1 of Phosphatidylinositol transfer protein beta isoform [ipi.HUMAN.fasta.20090807]
  • Tax_Id=9606 Isoform 1 of Phosphatidylinositol transfer protein beta isoform [IPI_human_3.26.fasta]
  • [human_BMb_040710_contam.fasta]
  • phosphatidylinositol transfer protein beta isoform [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • P48739;B3KYB8;Q8N5W1; RecName: Full=Phosphatidylinositol transfer protein beta isoform; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Isoform 1 of Phosphatidylinositol transfer protein beta isoform OS=Homo sapiens GN=PITPNB [011711_HMR.fasta]
  • GeneSymbol=PITPNB Synonyms=PI-TP-beta|PtdInsTP|VIB1B phosphatidylinositol transfer protein beta isoform [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00334907.3|SWISS-PROT:P48739-1|ENSEMBL:ENSP00000334738|REFSEQ:NP_036531|H-INV:HIT000038406|VEGA:OTTHUMP00000198846 Tax_Id=9606 Gene_Symbol=PITPNB Isoform 1 of Phosphatidylinositol transfer protein beta isoform [ipi.HUMAN.20110912.fasta]
  • Phosphatidylinositol transfer protein beta isoform GN=PITPNB [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 271 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLIKEFRVV LPCSVQEYQV GQLYSVAEAS KNETGGGEGI EVLKNEPYEK DGEKGQYTHK  60
   61 IYHLKSKVPA FVRMIAPEGS LVFHEKAWNA YPYCRTIVTN EYMKDDFFIK IETWHKPDLG 120
  121 TLENVHGLDP NTWKTVEIVH IDIADRSQVE PADYKADEDP ALFQSVKTKR GPLGPNWKKE 180
  181 LANSPDCPQM CAYKLVTIKF KWWGLQSKVE NFIQKQEKRI FTNFHRQLFC WIDKWIDLTM 240
  241 EDIRRMEDET QKELETMRKR GSVRGTSAAD V

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..271] PSI-BLAST 140.0 Rat PITP-Beta Complexed to Phosphatidylcholine

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phospholipid transporter activity
    		•  5.13837461289632 bayes_pls_golite062009
  • lipid transporter activity
    		•  4.4358073696145 bayes_pls_golite062009
  • phosphatidylinositol transporter activity
    		•  2.88424241201993 bayes_pls_golite062009
  • transporter activity
    		•  2.27726025087174 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.15798050058248 bayes_pls_golite062009
  • binding
    		•  2.03322388415011 bayes_pls_golite062009
  • sterol binding
    		•  1.50607153716429 bayes_pls_golite062009
  • cholesterol binding
    		•  1.15123926171731 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.09413284791115 bayes_pls_golite062009
  • phosphatidylcholine transmembrane transporter activity
    		•  0.917631923888787 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.584604660695011 bayes_pls_golite062009
  • cholesterol transporter activity
    		•  0.478721911308239 bayes_pls_golite062009
  • protein binding
    		•  0.43929659331502 bayes_pls_golite062009
  • sterol transporter activity
    		•  0.35901111584592 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.295257921753146 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.286459038638072 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.265156292873733 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.256503527440737 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.21859262454477 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.215063584310921 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.214776368903272 bayes_pls_golite062009
  • lipid binding
    		•  0.144022082146249 bayes_pls_golite062009
  • steroid binding
    		•  0.136743971526566 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0954103313829049 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0415343979510595 bayes_pls_golite062009
  • catalytic activity
    		•  0.0116392906163881 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.00274551209125462 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle