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Protein Overview: Nipped-A-PA

General Information:
Name(s) found: Nipped-A-PA / FBpp0085431 [FlyBase]
Description(s) found:
Found 9 descriptions.
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  • The gene Nipped-A is referred to in FlyBase by the symbol Dmel\Nipped-A (CG33554, FBgn0053554). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:1065506..1138553. It has the cytological map location 41E1-41E3. There is experimental evidence that it has the molecular function</span>: transcription regulator activity. There is experimental evidence that it is involved in the biological process</span>: cytokinesis; regulation of transcription; phagocytosis, engulfment. 49 alleles are reported. The phenotypes of these alleles are annotated with: ocellus; wing. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 3803 amino acids

    Gene Ontology:
    Cellular Component: SAGA complex [NAS]
    histone acetyltransferase complex [IDA]
    Biological Process: phagocytosis, engulfment [IMP]
    cytokinesis [IMP]
    regulation of transcription [IDA]
    Molecular Function: transcription regulator activity [IDA]
    protein kinase activity [NAS]
    phosphotransferase activity, alcohol group as acceptor [IEA]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVIENVPVN TFRNYLNILN DSSSKDELKL KATQELSEHF EMIMQSPAYP SFLDNSLKIF  60
   61 MRILQDGEPQ FIQENTMQHN LSKDVMLVAT ATVLAMNRLG TFVSCRALLD SGSQLHLIHP 120
  121 YLHISFNLRR RNRSTGVGDF SFDTHEMIHR LPITESLRQH VKTIITMMLK ILKTDNEENV 180
  181 LVCLRIIIEL HKHFRPSFNS EGMVEIPKER LDESHALEVI VTDLCGPFFY KPEACNKAPV 240
  241 KCYIQLFLGF VKEIYTNLPN HLTSIFETSN DVWVTDLKDL NLEVLLSESY SVRTIHVEKA 300
  301 LDSNSQQQII RVDDEELIDD IIRDSRCFNS SAKLLHAFAK VSPIKSLFSS SGRAKVSIEK 360
  361 GPSSVPTKRL NLMKNCPKEA AHLRKELLIA ARHIFATDLR QKFIPSIEQL FDEDLLIGKG 420
  421 VTLDSIRPLA YSTLADLAHH VRQSLNIDVL IKAVNLFSKN VHDESLAVGI QTMSCKLLLN 480
  481 LVDCLRHHSE TEPQRSKALL SKLLKVFVKK FETIAKIQLP LIIQKCKGHA FSGALVNSSG 540
  541 NASLSHINAP DLKDDISNIQ VSASGSQWIY SVNVAEFRSL VKTLVGGVKT ITWGFFNSKF 600
  601 QLTDTKLANH EKIFGPEIVC SYIDLVYYAM EALDIYTINV NPNQQRTSGL ISRSKEEKEV 660
  661 LEHFSGIFLM MHSQNFQEIF STTINFLVER IYKNQSLQVI ANSFLANPTT SPLFATVLVE 720
  721 YLLNKMEEMG SNLERSNLYL RLFKLVFGSV SLFPVENEQM LRPHLHKIVN RSMELALISE 780
  781 EPYNYFLLLR ALFRSIGGGS HDLLYQEFLP LLPNLLEGLN RLQSGFHKQH MRDLFVELCL 840
  841 TVPVRLSSLL PYLPMLMDPL VSALNGSPTL ISQGLRTLEL CVDNLQPDFL YDHIQPVRAA 900
  901 LMQALWKTLR NQDNAALVAF RVLGKFGGGN RKMMVEPQAL SYIINDKPTI SIVTYFQEYE 960
  961 TPIDFPVDEA IKSAFRALGS NSTDQFYRRQ SWEVIRCFLA AFISLDDEKH MLLKLFTHVD1020
 1021 FVENKIMNWS TFQHKAGNET VRETHQTALI GMLVASATKD LRDSVCPVMA AVVRHYTMVA1080
 1081 IAQQAGPFPQ KGYQATHGID PMILIDALAS CMGHEEKELC KPGIACMGII LDTATNIMGN1140
 1141 KDRACKLPII QYLAEKMVSL CYDRPWYSKV GGCQAIQFLC KHMSLRALFQ NLFNFLKAFM1200
 1201 FVLMDLEGDV SNGAIEITKS YMKSMLEICL TPINECYKNI DLKDLQAKAT YEVIHELVRH1260
 1261 ITSPNTIVRE ESMVLLKHIG TIQSKTVSEV MDPHKDVLAD IIPPKKHLLR HQPANAQIGL1320
 1321 MDGNTFCTTL EPRLFTIDLT NTYHKLFFHE LLTLSEAEDA TLAKLDCYKN VPNLIPLRTS1380
 1381 ALRALAACHY ISDIGYKEKI INIIFKVMES DKSELQTTAF HCMKHFITGV TLEKEKVQSA1440
 1441 MRPLLLKLGD HRNLSIPAIK RLSYFTQIFP QMFNEKLSEQ ILQHCSKIME IFVSEYKSTS1500
 1501 PNVNFFASSK GGEYEQKIVI LIEMFFYISA SVKYIEKLCQ LVLKTEKNLM IEASSPYREA1560
 1561 LIKFLQRFPT ETVDLFLTES LMIDPQWNRL FIYLLKHETG VSFRAVIKSS RYNNLIHYLN1620
 1621 THTEFPEALK YEIQHQAVLI IFTLMESDDQ WIPTRQDIVD ALKNCWQNYL STLSSEDVLC1680
 1681 DLWHLIGKIL LHYFSNNTND IELLFQLLRA LCFRFIPDVY FLRDFLQHTV AQSFTVNWKR1740
 1741 NAFFYFVENF NNSFLSEELK AKIITAVIIP CFAVSFDKGE GNKLIGAPPT PYQEDEKNIV1800
 1801 SVFINKVFDP DKQYDDAVRI ALLQLACLLV ERASQHIHDG DANNKRQGNK LRRLMTFAWP1860
 1861 CLLSKSSVDP TARYHGHLLL SHIIARLAIH KKIVLQVFHS LLKGHALEAR SIVKQALDVL1920
 1921 TPAMPLRMED GNTMLTHWTK KIIVEEGHAM QQLFHILQLI IRHYKVYFPV RHQLVQHLIN1980
 1981 YMQRLGFPPT ASIEHKKLAV DLAEVIIKWE LHRIKDDRET KTDGTEEELI QESSVKRSGI2040
 2041 DLVETRKKSF DIIRETTVQG KCVMLLKMAM RPEIWPQPFD IKLNWLDKVL ATVETPHHNL2100
 2101 NNICTGIDFL TFLTTILSPD QLVSIIRPVQ RGLSLCIIHQ NTRIVRLMHM FLTRIMAIFP2160
 2161 PDTQHKHEDL DLLYTAVSKM IAENLTSYEK SPQPNASSLF GTLMILKACT TNNASYIDRI2220
 2221 LVQFIRVLNH LTRDHINTIG GNTVISQSPD SNALPLELLV LSLELIKNRI FVMSVEIRKL2280
 2281 FIGTILVSLI EKSTEVKIIK CIIKMLDEWI KTKEPNVMTQ VPSIREKSAL LVKLMQNVEK2340
 2341 KFTDEIELNI QFLEIINFIY RDEILKQTEL TNKLEGAFLN GLRFQNPNVR SKFFEILDSS2400
 2401 MRRRLHDRLL YIICSQAWDT IGSHYWIKQC IELLILTANT MMQIQCSNEQ FKIPSITSVI2460
 2461 PVNSSETQEN SFVSFLSSHS ESFDIIQTVD DKDDVYDIDL NADRKEDCQQ ILPNRRVTLV2520
 2521 ELVYKQAEFL EANRNIRTDQ MLVATSQLCH IDTQLAQSVW LSMFPRIWSI FTEDQRCNIT2580
 2581 KELIPFLSSG TNVNQKDCHP STLNTFVESL TKCAPPIYIP PNLLAYLGKS HNLWHRAILV2640
 2641 LEDMAVNQSM QSKDIDGGEN QFSDLDVQQS NNIFDSLSKM YSSMHEEDLW AGLWLKFAHY2700
 2701 PETNIAVSYE QMGFFEEAQG AYDLAMTKFK QDLSNGVVNT YVNSELLLWE NHWMRCAKEL2760
 2761 NQWDILLDYA QTNKDKNMFL ILESSWRVPD WNLMKIALAK TEQCYLKHYG FKINLYKGYL2820
 2821 SILHQEERQT GNIERYVEIA SSLCIREWRR LPNIVSHIHL PYLQASQQIM ELHEASQIHQ2880
 2881 GLAQSRNNSL HDMKAIVKTW RNRLPIISDD LSHWSDIFTW RQHHYQIITQ HLEQQSDQGS2940
 2941 TMLGVHASAQ AIISFGKIAR KHNLTGVCQE TLSRIYTIPS VPIVDCFQKI RQQVKCYLQM3000
 3001 PSTSGKNEIN EALEVIESTN LKYFTGEMNA EFYALKGLLL AQIGRSEEAG KSFSVAAQLH3060
 3061 DGLTKAWAMW GDYMEQIFLK ERKITLAVDA LICYLQASRN QIESKTRKYI AKVLWFLSYD3120
 3121 NNTKILISTL EKHVAGIPPS YWLPWIPQLL CCLEQFEGDV ILNLLSQIGR LYPQAVYFPI3180
 3181 RTLYLTLKIE QREKHKTAEQ AVKSSCSNID GTTLSFGRGA SHGNIPSINP IKATPPMWRC3240
 3241 SKVMQLQREV HPTILSSLEG IVDQMVWFRE SWTEEVLRQL RQGLIKCYAI AFEKRDTVQH3300
 3301 STITPHTLHF VKKLGSTFGI GIENVPGSVT SSISNSAASE SLARRAQVTF QDPVFQKMKE3360
 3361 QFTNDFDFSK PGAMKLHNLI SKLKTWIKVL ETKVKKLPTS FLIEDKCRFL SNFSQKTAEV3420
 3421 ELPGELLIPL SSHYYVRIAR FMPRVEIVQK NNTAARRLYI RGTNGKIYPY LVVLDSGLGD3480
 3481 ARREERVLQL KRMLNYYLEK QKETSRRFLN ITVPRVVPIS PQMRLAEDNP NSISLLKIFK3540
 3541 KCCQSMQVDY DMPIVKYYDR LSEVQARGTP TTHTLLREIF SEIQWTMVPK TLLKHWALKT3600
 3601 FLAATDFWHF RKMLTLQLAL AFLCEHALNL TRLNADMMYL HQDSGLMNIS YFKFDVNDDK3660
 3661 CQLNQHRPVP FRLTPNVGEF ITHFGITGPL SAAIVATARC FIQPNYKLSS ILQTILRDEI3720
 3721 IALQKKGFRE CKLIEGSEDR YSDGNCMEHS VNIVNSAVDI IMTRFNKISY FDSIENKKIS3780
 3781 VLVQSATNID NLCRMDPAWH PWL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.65

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle