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Protein Overview: YCIR_ECOLI

General Information:
Name(s) found: YCIR_ECOLI [Swiss-Prot]
Description(s) found:
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  • pir||H64876 probable membrane protein yciR - Escherichia coli (strain K-12) [NCBI NR]
  • gi|2495597|sp|P77334.1|GMR_ECOLI RecName: Full=Protein gmr [NCBI NR]
  • dbj|BAA14847.1| ORF_ID:o255#12~similar to [SwissProt Accession Number Q11024] [Escherichia coli] [NCBI NR]
  • gi|1742099|dbj|BAA14839.1| modulator of Rnase II stability [Escherichia coli W3110] [NCBI NR]
  • Hypothetical protein yciR - Escherichia coli [Swiss-Prot]
  • RNase II modulator; hypothetical protein [Escherichia coli K12]gi|1787541|gb|AAC74367.1| orf, hypothetical protein; RNase II modulator [Escherichia coli K12]gi|7466809|pir||H64876 probable membrane protein yciR - Escherichia coli (strain K-12)gi|249559 [nrdb_11152004_Chlamydomonas]
  • Protein gmr [NCBI-RefSeq_human_na_08-09-2006_reversed.fasta]
  • Cyclic di-GMP phosphodiesterase Gmr OS=Escherichia coli (strain K12) GN=gmr PE=1 SV=1 [uniprot-Ecoli-reviewed-110511.fasta]
    • Organism: Escherichia coli
    Length: 661 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTVRESTTL YNFLGSHNPY WRLTESSDVL RFSTTETTEP DRTLQLSAEQ AARIREMTVI  60
   61 TSSLMMSLTV DESDLSVHLV GRKINKREWA GNASAWHDTP AVARDLSHGL SFAEQVVSEA 120
  121 HSAIVILDSR GNIQRFNRLC EDYTGLKEHD VIGQSVFKLF MSRREAAASR RNNRVFFRSG 180
  181 NAYEVELWIP TCKGQRLFLF RNKFVHSGSG KNEIFLICSG TDITEERRAQ ERLRILANTD 240
  241 SITGLPNRNA MQDLIDHAIN HADNNKVGVV YLDLDNFKKV NDAYGHLFGD QLLRDVSLAI 300
  301 LSCLEHDQVL ARPGGDEFLV LASNTSQSAL EAMASRILTR LRLPFRIGLI EVYTSCSVGI 360
  361 ALSPEHGSDS TAIIRHADTA MYTAKEGGRG QFCVFTPEMN QRVFEYLWLD TNLRKALEND 420
  421 QLVIHYQPKI TWRGEVRSLE ALVRWQSPER GLIPPLDFIS YAEESGLIVP LGRWVILDVV 480
  481 RQVAKWRDKG INLRVAVNIS ARQLADQTIF TALKQVLQEL NFEYCPIDVE LTESCLIEND 540
  541 ELALSVIQQF SQLGAQVHLD DFGTGYSSLS QLARFPIDAI KLDQVFVRDI HKQPVSQSLV 600
  601 RAIVAVAQAL NLQVIAEGVE SAKEDAFLTK NGINERQGFL FAKPMPAVAF ERWYKRYLKR 660
  661 A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..97] PSI-BLAST 8.0 No description for 2gj3A was found.
    2 View Details [98..237] FFAS03 5.92 Crystal Structure of the heme PAS sensor domain of Ec DOS (ferric form)
    3 View Details [238..403] PSI-BLAST 15.0 Response regulator PleD in complex with c-diGMP
    4 View Details [404..661] PSI-BLAST 69.0 No description for 2r6oA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.11810529315597 bayes_pls_golite062009
  • protein binding
    		•  1.35116033536319 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.972708865275432 bayes_pls_golite062009
  • two-component response regulator activity
    		•  0.798874220332901 bayes_pls_golite062009
  • DNA binding
    		•  0.737759263759466 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.626552612035066 bayes_pls_golite062009
  • signal transducer activity
    		•  0.386333593205398 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.386333593205398 bayes_pls_golite062009
  • transcription factor activity
    		•  0.233622464289646 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.00745761267362077 bayes_pls_golite062009
    3
    Term Confidence Notes
  • two-component response regulator activity
    		•  1.88327307771701 bayes_pls_golite062009
  • signal transducer activity
    		•  1.7438872646629 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.7438872646629 bayes_pls_golite062009
  • two-component sensor activity
    		•  0.300567386918242 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  0.276515698624029 bayes_pls_golite062009
  • binding
    		•  0.145546551776301 bayes_pls_golite062009
  • cyclase activity
    		•  0.135549728707442 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  0.132981161220456 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle