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Protein Overview: SRBS1_MOUSE

General Information:
Name(s) found: SRBS1_MOUSE [Swiss-Prot]
Description(s) found:
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  • gi|51701938|sp|Q62417.2|SRBS1_MOUSE RecName: Full=Sorbin and SH3 domain-containing protein 1; AltName: Full=Ponsin; AltName: Full=c-Cbl-associated protein; Short=CAP; AltName: Full=SH3 domain protein 5; AltName: Full=SH3P12 [NCBI NR]
  • Sorbin and SH3 domain-containing protein 1 OS=Mus musculus GN=Sorbs1 PE=1 SV=2 [Swiss-Prot]
  • (Q62417) Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12) [Swiss-Prot]
  • Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12) [nrdb_11152004_Chlamydomonas]
  • Splice Isoform 1 of Sorbin and SH3 domain-containing protein 1 [ipi.MOUSE.v3.06.fasta]
  • Tax_Id=10090 Splice Isoform 1 of Sorbin and SH3 domain-containing protein 1 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta]
  • Tax_Id=10090 Gene_Symbol=Sorbs1 Isoform 1 of Sorbin and SH3 domain-containing protein 1 [mouse-ipi-250309-contam.fasta]
  • Tax_Id=10090 Gene_Symbol=Sorbs1 Isoform 1 of Sorbin and SH3 domain-containing protein 1 ENSMUSG00000025006 IPI00129707 IPI00468140 IPI00129708 IPI00458043 IPI00655029 IPI00125895 IPI00458047 IPI00458048 [IPIxENS.MOUSE_plus_REVERSE.fasta]
  • IPI:IPI00468140.2|SWISS-PROT:Q62417-1|ENSEMBL:ENSMUSP00000025973 Tax_Id=10090 Gene_Symbol=Sorbs1 Isoform 1 of Sorbin and SH3 domain-containing protein 1 [ipi.MOUSE.fasta.20090209]
  • Isoform 1 of Sorbin and SH3 domain-containing protein 1 OS=Mus musculus GN=Sorbs1 [011711_HMR.fasta]
  • sp|Q62417|SRBS1_MOUSE Sorbin and SH3 domain-containing protein 1 OS=Mus musculus GN=Sorbs1 PE=1 SV=2 [uniprot.sptr.mouse.20130102]
    • Organism: Mus musculus
    Length: 1290 amino acids

    Gene Ontology:
    Cellular Component: cytoskeleton [IEA]
    cytoplasm [IEA]
    cell-cell adherens junction [IDA]
    cell-substrate adherens junction [IDA]
    stress fiber [IDA]
    membrane raft [IDA]
    membrane [IDA]
    cell junction [IEA]
    cytosol [IDA]
    plasma membrane [IEA]
    flotillin complex [IC]
    Biological Process: cellular response to insulin stimulus [IC][IMP]
    insulin receptor signaling pathway [IC][IDA]
    positive regulation of establishment of protein localization in plasma membrane [IMP]
    positive regulation of glucose import [IMP]
    glucose transport [IDA]
    focal adhesion assembly [IDA]
    stress fiber assembly [IDA]
    transport [IEA]
    positive regulation of glycogen biosynthetic process [IMP]
    positive regulation of lipid biosynthetic process [IMP]
    Molecular Function: protein kinase binding [IDA]
    protein binding [IPI]
    SH3/SH2 adaptor activity [IPI]
    insulin receptor binding [IDA][IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSECDVGSS KAVVNGLASG NHGPDKDMDP TKICTGKGTV TLRASSSYRG TPSSSPVSPQ  60
   61 ESPKHESKSG LEPEDPSADE WKLSSSADTN GNAQPSPLAA KGYRSVHPSL SADKPQGSPL 120
  121 LNEVSSSHIE TDSQDFPPTS RPSSAYPSTT IVNPTIVLLQ HNRDPASERR AGEQDPVPTP 180
  181 AELTSPGRAS ERRAKDASRR VVRSAQDLSD VSTDEVGIPL RNTERSKDWY KTMFKQIHKL 240
  241 NRDDDSDVHS PRYSFSDDTK SPLSVPRSKS EMNYIEGEKV VKRSATLPLP ARSSSLKSSP 300
  301 ERNDWEPLDK KVDTRKYRAE PKSIYEYQPG KSSVLTNEKM SRDISPEEID LKNEPWYKFF 360
  361 SELEFGRPTN LEKDLSFCQA ELEADLEKVE TVNKSPSANS PQSSAVSPTP DITSEPPGYI 420
  421 YSSNFHAVKR ESDGTPGGLA SLENERQIYK SVLEGGDIPL QGLSGLKRPS SSASTKVDRK 480
  481 GGNAHMISSS SVHSRTFHTS NALGPGCKHK KPLSAAKACI SEILPSKFKP RLSAPSALLQ 540
  541 EQKSVLLPSE KAQSCENLCV SLNDSKRGLP LRVGGSIENL LMRSRRDYDS KSSSTMSLQE 600
  601 YGTSSRRPCP LSRKAGLHFS MFYRDMHQIN RAGLSLGSIS SSSVRDLASH FERSSLTLAR 660
  661 GELGASQEGS EHIPKHTVSS RITAFEQLIQ RSRSMPSLDF SGRLSKSPTP VLSRSGLTSA 720
  721 RSAESLLEST KLRPREMDGM DSGGVYASPT CSNMADHALS FRSLVPSEPL SICSDELDHC 780
  781 SNVSNDSREG SGGSVHGDFP KHRLNKCKGT CPASYTRFTT IRKHEQQSSR QSDWRSDSRG 840
  841 DKNSLLRNIH LMSPLPFRLK KPLQQHPRQP PPSDSSESPA GQKADLPCHD PQDQPHSAGK 900
  901 PQVPTRLSSR HTMARLSHNS EPPLDRPAGL EDCTRAINNG NPVPYSDHGL DRNNNPQSEL 960
  961 AAAHGDSESP RHFIPADYLE STEEFIRRRH DDKEKLLADQ RRLKREQEEA DIAARRHTGV1020
 1021 IPTHHQFITN ERFGDLLNID DTAKRKSGLE MRPARAKFDF KAQTLKELPL QKGDVVYIYR1080
 1081 QIDQNWYEGE HHGRVGIFPR TYIELLPPAE KAQPRKLAPV QVLEYGEAIA KFNFNGDTQV1140
 1141 EMSFRKGERI TLLRQVDENW YEGRIPGTSR QGIFPITYVD VLKRPLVKTP VDYIDLPYSS1200
 1201 SPSRSATVSP QQPQAQQRRV TPDRSQPSLD LCSYQALYSY VPQNDDELEL RDGDIVDVME1260
 1261 KCDDGWFVGT SRRTRQFGTF PGNYVKPLYL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle